Genular: Defining Cellular Identity and Function

Details for: Ccnd2

Gene ID: 12444

Symbol: Ccnd2

Ensembl ID: ENSMUSG00000000184

Description: cyclin D2

Associated with

Cell cycle, mitotic
(R-MMU-69278)
Cyclin d associated events in g1
(R-MMU-69231)
Drug-mediated inhibition of cdk4/cdk6 activity
(R-MMU-9754119)
G1 phase
(R-MMU-69236)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Mitotic g1 phase and g1/s transition
(R-MMU-453279)
Regulation of runx1 expression and activity
(R-MMU-8934593)
Rna polymerase ii transcription
(R-MMU-73857)
Transcriptional regulation by runx1
(R-MMU-8878171)
Adult locomotory behavior
(GO:0008344)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Cellular response to x-ray
(GO:0071481)
Centrosome
(GO:0005813)
Chromatin
(GO:0000785)
Cyclin-dependent protein kinase holoenzyme complex
(GO:0000307)
Cyclin-dependent protein serine/threonine kinase activator activity
(GO:0061575)
Cyclin-dependent protein serine/threonine kinase regulator activity
(GO:0016538)
Cyclin d2-cdk4 complex
(GO:0097129)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
G1/s transition of mitotic cell cycle
(GO:0000082)
Long-term memory
(GO:0007616)
Membrane
(GO:0016020)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of cardiac muscle cell differentiation
(GO:2000726)
Nuclear membrane
(GO:0031965)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of cardiac muscle cell proliferation
(GO:0060045)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cyclin-dependent protein serine/threonine kinase activity
(GO:0045737)
Positive regulation of epithelial cell proliferation
(GO:0050679)
Positive regulation of g1/s transition of mitotic cell cycle
(GO:1900087)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)
Regulation of cell cycle
(GO:0051726)
Regulation of cyclin-dependent protein serine/threonine kinase activity
(GO:0000079)

Other Information

Proteins

G1/S-specific cyclin-D2

Genular Protein ID: 1934194588

Symbol: CCND2_MOUSE

Name: G1/S-specific cyclin-D2

UniProtKB Accession Codes:

P30280

Database IDs:

Citations:

PubMed ID: 1372445

Title: Cloning of a D-type cyclin from murine erythroleukemia cells.

PubMed ID: 1372445

DOI: 10.1073/pnas.89.6.2444

PubMed ID: 1827757

Title: Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle.

PubMed ID: 1827757

DOI: 10.1016/0092-8674(91)90101-4

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 33854232

Title: AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.

PubMed ID: 33854232

DOI: 10.1038/s41586-021-03422-5

PubMed ID: 33854235

Title: CRL4AMBRA1 is a master regulator of D-type cyclins.

PubMed ID: 33854235

DOI: 10.1038/s41586-021-03445-y

Sequence Information:

Length: 289
Mass: 32897
Checksum: 58F322771DD1DA3D
Sequence:

MELLCCEVDP VRRAVPDRNL LEDRVLQNLL TIEERYLPQC SYFKCVQKDI QPYMRRMVAT 
WMLEVCEEQK CEEEVFPLAM NYLDRFLAGV PTPKTHLQLL GAVCMFLASK LKETIPLTAE 
KLCIYTDNSV KPQELLEWEL VVLGKLKWNL AAVTPHDFIE HILRKLPQQK EKLSLIRKHA 
QTFIALCATD FKFAMYPPSM IATGSVGAAI CGLQQDDEVN TLTCDALTEL LAKITHTDVD 
CLKACQEQIE ALLLNSLQQF RQEQHNAGSK SVEDPDQATT PTDVRDVDL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ccnd2

Associated with

Other Information

Cloning of a D-type cyclin from murine erythroleukemia cells. PubMed ID: 1372445

Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle. PubMed ID: 1827757

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity. PubMed ID: 33854232