Genular: Defining Cellular Identity and Function

Details for: Cd2

Gene ID: 12481

Symbol: Cd2

Ensembl ID: ENSMUSG00000027863

Description: CD2 antigen

Associated with

Cell-cell adhesion
(GO:0098609)
Cell-cell junction
(GO:0005911)
Cell adhesion
(GO:0007155)
Cell surface
(GO:0009986)
Cytoplasmic side of plasma membrane
(GO:0009898)
External side of plasma membrane
(GO:0009897)
Extracellular region
(GO:0005576)
Golgi apparatus
(GO:0005794)
Heterotypic cell-cell adhesion
(GO:0034113)
Identical protein binding
(GO:0042802)
Membrane
(GO:0016020)
Natural killer cell activation
(GO:0030101)
Natural killer cell mediated cytotoxicity
(GO:0042267)
Nucleoplasm
(GO:0005654)
Plasma membrane
(GO:0005886)
Positive regulation of interleukin-8 production
(GO:0032757)
Positive regulation of tumor necrosis factor production
(GO:0032760)
Positive regulation of type ii interferon production
(GO:0032729)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)
Protein self-association
(GO:0043621)
Receptor tyrosine kinase binding
(GO:0030971)
Signaling receptor binding
(GO:0005102)

Other Information

Proteins

T-cell surface antigen CD2

Genular Protein ID: 3483109537

Symbol: CD2_MOUSE

Name: T-cell surface antigen CD2

UniProtKB Accession Codes:

P08920 Q61394

Database IDs:

Citations:

PubMed ID: 2440689

Title: The murine homologue of the T lymphocyte CD2 antigen: molecular cloning, chromosome assignment and cell surface expression.

PubMed ID: 2440689

DOI: 10.1002/eji.1830170718

PubMed ID: 2820751

Title: Murine and human T11 (CD2) cDNA sequences suggest a common signal transduction mechanism.

PubMed ID: 2820751

DOI: 10.1002/eji.1830170922

PubMed ID: 2894031

Title: Exon-intron organization and sequence comparison of human and murine T11 (CD2) genes.

PubMed ID: 2894031

DOI: 10.1073/pnas.85.5.1615

PubMed ID: 3257775

Title: Molecular cloning of the murine homologue of CD2. Homology of the molecule to its human counterpart T11.

PubMed ID: 3257775

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9741631

Title: A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts.

PubMed ID: 9741631

DOI: 10.1016/s0092-8674(00)81608-6

PubMed ID: 12530983

Title: The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse.

PubMed ID: 12530983

DOI: 10.1016/s1074-7613(02)00516-2

Sequence Information:

Length: 344
Mass: 38415
Checksum: CFD12FCBD1444450
Sequence:

MKCKFLGSFF LLFSLSGKGA DCRDNETIWG VLGHGITLNI PNFQMTDDID EVRWVRRGTL 
VAEFKRKKPP FLISETYEVL ANGSLKIKKP MMRNDSGTYN VMVYGTNGMT RLEKDLDVRI 
LERVSKPMIH WECPNTTLTC AVLQGTDFEL KLYQGETLLN SLPQKNMSYQ WTNLNAPFKC 
EAINPVSKES KMEVVNCPEK GLSFYVTVGV GAGGLLLVLL VALFIFCICK RRKRNRRRKD 
EELEIKASRT STVERGPKPH STPAAAAQNS VALQAPPPPG HHLQTPGHRP LPPGHRTREH 
QQKKRPPPSG TQIHQQKGPP LPRPRVQPKP PCGSGDGVSL PPPN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cd2

Associated with

Other Information

The murine homologue of the T lymphocyte CD2 antigen: molecular cloning, chromosome assignment and cell surface expression. PubMed ID: 2440689

Murine and human T11 (CD2) cDNA sequences suggest a common signal transduction mechanism. PubMed ID: 2820751

Exon-intron organization and sequence comparison of human and murine T11 (CD2) genes. PubMed ID: 2894031

Molecular cloning of the murine homologue of CD2. Homology of the molecule to its human counterpart T11. PubMed ID: 3257775

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts. PubMed ID: 9741631

The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse. PubMed ID: 12530983