Genular: Defining Cellular Identity and Function

Details for: Scarb2

Gene ID: 12492

Symbol: Scarb2

Ensembl ID: ENSMUSG00000029426

Description: scavenger receptor class B, member 2

Associated with

Cargo recognition for clathrin-mediated endocytosis
(R-MMU-8856825)
Clathrin-mediated endocytosis
(R-MMU-8856828)
Membrane trafficking
(R-MMU-199991)
Vesicle-mediated transport
(R-MMU-5653656)
Aminophospholipid transport
(GO:0015917)
Cargo receptor activity
(GO:0038024)
Cholesterol binding
(GO:0015485)
Cytoplasm
(GO:0005737)
Endocytic vesicle membrane
(GO:0030666)
Endosome to plasma membrane protein transport
(GO:0099638)
Enzyme binding
(GO:0019899)
Lysosomal lumen
(GO:0043202)
Lysosomal membrane
(GO:0005765)
Lysosome
(GO:0005764)
Membrane
(GO:0016020)
Phosphatidylcholine binding
(GO:0031210)
Phosphatidylserine binding
(GO:0001786)
Plasma membrane
(GO:0005886)
Positive regulation of neuron projection development
(GO:0010976)
Protein-folding chaperone binding
(GO:0051087)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Protein targeting to lysosome
(GO:0006622)
Receptor-mediated endocytosis
(GO:0006898)
Regulation of carbohydrate catabolic process
(GO:0043470)
Regulation of glucosylceramidase activity
(GO:1905123)
Scavenger receptor activity
(GO:0005044)
Sensory perception of sound
(GO:0007605)

Other Information

Proteins

Lysosome membrane protein 2

Genular Protein ID: 2578280442

Symbol: SCRB2_MOUSE

Name: Lysosome membrane protein 2

UniProtKB Accession Codes:

O35114 Q3UNF8

Database IDs:

Citations:

PubMed ID: 9399579

Title: Identification and characterization of a major lysosomal membrane glycoprotein, LGP85/LIMP II in mouse liver.

PubMed ID: 9399579

DOI: 10.1093/oxfordjournals.jbchem.a021820

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18022370

Title: LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidase.

PubMed ID: 18022370

DOI: 10.1016/j.cell.2007.10.018

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 24162852

Title: Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36.

PubMed ID: 24162852

DOI: 10.1038/nature12684

Sequence Information:

Length: 478
Mass: 54044
Checksum: 55724B77855470DF
Sequence:

MGRCCFYTAG TLSLLLLVTS VTLLVARVFQ KAVDQTIEKN MVLQNGTKVF NSWEKPPLPV 
YIQFYFFNVT NPEEILQGEI PLLEEVGPYT YRELRNKANI QFGENGTTIS AVTNKAYVFE 
RNQSVGDPNV DLIRTINIPL LTVVDLAQLT LLRELIEAML KAYQQKLFVI HTVHELLWGY 
KDEILSLVHI FKPDVSPNFG LFYERNGTND GEYVFLTGED NYLNFSKIVE WNGKTSLDWW 
TTDTCNMING TDGDSFHPLI SKDEVLYLFP SDLCRSVHIT FSSFENVEGL PAFRYKVPAE 
ILANTSENAG FCIPEGNCMD SGVLNISICK NGAPIIMSFP HFYQADEKFV SAIKGMHPNK 
EEHESFVDIN PLTGIILRGA KRFQINTYVR KLDDFVETGD IRTMVFPVMY LNESVLIDKE 
TANQLKSVIN TTLVVTNIPY IIMALGVFFG LVFTWLACRG QGSMDEGTAD ERAPLIRT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Scarb2

Associated with

Other Information

Identification and characterization of a major lysosomal membrane glycoprotein, LGP85/LIMP II in mouse liver. PubMed ID: 9399579

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidase. PubMed ID: 18022370

Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins. PubMed ID: 19349973

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36. PubMed ID: 24162852