Details for: ADH1B

Gene ID: 125

Symbol: ADH1B

Ensembl ID: ENSG00000196616

Description: alcohol dehydrogenase 1B (class I), beta polypeptide

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 28.0390
    Cell Significance Index: 173.4700
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 26.9755
    Cell Significance Index: 71.1600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 13.4277
    Cell Significance Index: -12.8200
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 12.2883
    Cell Significance Index: 83.2600
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 10.1730
    Cell Significance Index: 44.2900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 7.1276
    Cell Significance Index: 139.1100
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 5.5133
    Cell Significance Index: 69.4300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 5.2597
    Cell Significance Index: 88.6000
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 2.3022
    Cell Significance Index: 33.0600
  • Cell Name: fibroblast of the aortic adventitia (CL0002547)
    Fold Change: 1.9482
    Cell Significance Index: 19.6600
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.8924
    Cell Significance Index: 30.3600
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.7907
    Cell Significance Index: 26.4300
  • Cell Name: theca cell (CL0000503)
    Fold Change: 1.6732
    Cell Significance Index: 9.8300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.3553
    Cell Significance Index: 38.8500
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 0.8603
    Cell Significance Index: 5.4100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.8313
    Cell Significance Index: 37.6800
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.8092
    Cell Significance Index: 4.6600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.8007
    Cell Significance Index: 40.4600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7569
    Cell Significance Index: 150.2000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6754
    Cell Significance Index: 128.5300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.5188
    Cell Significance Index: 16.6200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.4069
    Cell Significance Index: 8.4400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3362
    Cell Significance Index: 33.2600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3330
    Cell Significance Index: 300.6500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.2302
    Cell Significance Index: 2.1200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1809
    Cell Significance Index: 29.4200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1440
    Cell Significance Index: 15.6600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1317
    Cell Significance Index: 23.7400
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 0.1036
    Cell Significance Index: 0.8700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0864
    Cell Significance Index: 2.1600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0708
    Cell Significance Index: 4.2500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0628
    Cell Significance Index: 4.3500
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.0511
    Cell Significance Index: 0.7700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0312
    Cell Significance Index: 13.8100
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.0026
    Cell Significance Index: 0.0400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0071
    Cell Significance Index: -0.2500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0071
    Cell Significance Index: -13.3800
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -0.0083
    Cell Significance Index: -0.0800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0096
    Cell Significance Index: -17.7000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0101
    Cell Significance Index: -0.2200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0111
    Cell Significance Index: -0.3200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0118
    Cell Significance Index: -18.2100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0125
    Cell Significance Index: -9.4400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0145
    Cell Significance Index: -19.7200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0176
    Cell Significance Index: -13.0200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0206
    Cell Significance Index: -15.0900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0221
    Cell Significance Index: -14.0200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0224
    Cell Significance Index: -13.9800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0237
    Cell Significance Index: -13.3700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0275
    Cell Significance Index: -15.0300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0301
    Cell Significance Index: -4.1300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0312
    Cell Significance Index: -2.2100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0323
    Cell Significance Index: -0.7000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0342
    Cell Significance Index: -15.5200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0354
    Cell Significance Index: -12.7000
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0384
    Cell Significance Index: -0.6100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0490
    Cell Significance Index: -14.0900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0637
    Cell Significance Index: -13.4100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0638
    Cell Significance Index: -7.8400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0728
    Cell Significance Index: -14.6000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0795
    Cell Significance Index: -13.5700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0902
    Cell Significance Index: -13.1100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0972
    Cell Significance Index: -5.9600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1044
    Cell Significance Index: -12.1700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1085
    Cell Significance Index: -14.0200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1094
    Cell Significance Index: -8.4000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1207
    Cell Significance Index: -2.0200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1236
    Cell Significance Index: -5.8100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1349
    Cell Significance Index: -15.4500
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.1371
    Cell Significance Index: -1.6300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1405
    Cell Significance Index: -14.6300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1451
    Cell Significance Index: -14.8200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1823
    Cell Significance Index: -13.5900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1908
    Cell Significance Index: -15.1200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1922
    Cell Significance Index: -4.9400
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: -0.1993
    Cell Significance Index: -1.8500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2127
    Cell Significance Index: -14.3100
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.2210
    Cell Significance Index: -9.6100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.2298
    Cell Significance Index: -4.8100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2432
    Cell Significance Index: -12.6700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2500
    Cell Significance Index: -15.3700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2712
    Cell Significance Index: -7.5800
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: -0.2724
    Cell Significance Index: -2.9800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2779
    Cell Significance Index: -15.6000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3058
    Cell Significance Index: -14.2600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3070
    Cell Significance Index: -15.9500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3198
    Cell Significance Index: -11.7400
  • Cell Name: muscle fibroblast (CL1001609)
    Fold Change: -0.3477
    Cell Significance Index: -2.1300
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.3523
    Cell Significance Index: -3.6000
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: -0.3871
    Cell Significance Index: -3.6800
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: -0.4151
    Cell Significance Index: -4.1000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.4179
    Cell Significance Index: -14.6400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4237
    Cell Significance Index: -18.7400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.4312
    Cell Significance Index: -11.5600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4406
    Cell Significance Index: -15.3100
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.4434
    Cell Significance Index: -4.8200
  • Cell Name: fibroblast (CL0000057)
    Fold Change: -0.4484
    Cell Significance Index: -4.2100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4496
    Cell Significance Index: -14.7200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4622
    Cell Significance Index: -14.7200
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.4838
    Cell Significance Index: -6.7100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** The ADH1B gene is a member of the ADH family of enzymes, which are involved in the oxidation of alcohols, including ethanol. The ADH1B enzyme is a zinc-dependent, cytosolic enzyme that exhibits high specificity for ethanol, allowing for efficient metabolism of this toxic compound. Additionally, ADH1B is involved in the metabolism of retinoids, including retinol, retinoic acid, and retinyl esters, which are essential for maintaining normal vision and development. **Pathways and Functions:** The ADH1B gene is involved in several metabolic pathways, including: 1. **Alcohol dehydrogenase activity**: ADH1B catalyzes the oxidation of ethanol to acetaldehyde, a potent toxin that can cause cellular damage. 2. **Zinc-dependent oxidations**: ADH1B utilizes zinc ions as cofactors to facilitate the oxidation of various alcohols. 3. **Biological oxidations**: ADH1B participates in the oxidation of retinoids, including retinol, retinoic acid, and retinyl esters. 4. **Metabolism**: ADH1B is involved in the metabolic processing of ethanol and retinoids, regulating their levels and activity within cells. **Clinical Significance:** Dysregulation of the ADH1B gene has been implicated in various diseases and conditions, including: 1. **Alcohol use disorder**: Variants of the ADH1B gene have been associated with increased susceptibility to alcohol dependence and addiction. 2. **Retinopathy**: ADH1B deficiency has been linked to retinopathy, a condition characterized by damage to the retina and vision impairment. 3. **Metabolic disorders**: ADH1B is also involved in the metabolism of other compounds, such as retinoids, which can contribute to the development of metabolic disorders, such as obesity and diabetes. In conclusion, the ADH1B gene plays a vital role in various metabolic processes, including the oxidation of ethanol and the metabolism of retinoids. Understanding the functions and clinical significance of the ADH1B gene will provide valuable insights into the molecular mechanisms underlying its role in human health and disease, ultimately informing the development of novel therapeutic strategies for the treatment of related disorders.

Genular Protein ID: 1850908328

Symbol: ADH1B_HUMAN

Name: Alcohol dehydrogenase 1B

UniProtKB Accession Codes:

P00325 A8MYN5 B4DRS9 B4DVC3 Q13711 Q4ZGI9 Q96KI7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 28 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 9 DrugCentral 1 EC 1 EMBL 35 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 9 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 2 Rhea 5 SABIO-RK 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissLipids 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2986130

Title: Molecular cloning of a full-length cDNA for human alcohol dehydrogenase.

PubMed ID: 2986130

DOI: 10.1073/pnas.82.9.2703

PubMed ID: 3000832

Title: cDNA clones coding for the beta-subunit of human liver alcohol dehydrogenase have differently sized 3'-non-coding regions.

PubMed ID: 3000832

DOI: 10.1016/0014-5793(86)80111-9

PubMed ID: 2935533

Title: Molecular analysis of the human class I alcohol dehydrogenase gene family and nucleotide sequence of the gene encoding the beta subunit.

PubMed ID: 2935533

DOI: 10.1016/s0021-9258(17)35892-1

PubMed ID: 2935875

Title: Three human alcohol dehydrogenase subunits: cDNA structure and molecular and evolutionary divergence.

PubMed ID: 2935875

DOI: 10.1073/pnas.83.3.634

PubMed ID: 2679216

Title: Nucleotide sequence of the ADH2(3) gene encoding the human alcohol dehydrogenase beta 3 subunit.

PubMed ID: 2679216

DOI: 10.1111/j.1530-0277.1989.tb00383.x

PubMed ID: 2547609

Title: The genes for human alcohol dehydrogenases beta 1 and beta 2 differ by only one nucleotide.

PubMed ID: 2547609

DOI: 10.1111/j.1432-1033.1989.tb14931.x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6391920

Title: Human liver alcohol dehydrogenase. 1. The primary structure of the beta 1 beta 1 isoenzyme.

PubMed ID: 6391920

DOI: 10.1111/j.1432-1033.1984.tb08573.x

PubMed ID: 3397059

Title: Genotyping of human alcohol dehydrogenases at the ADH2 and ADH3 loci following DNA sequence amplification.

PubMed ID: 3397059

DOI: 10.1016/0888-7543(88)90004-3

PubMed ID: 15369820

Title: Kinetics of human alcohol dehydrogenase with ring-oxidized retinoids: effect of Tween 80.

PubMed ID: 15369820

DOI: 10.1016/j.abb.2004.07.002

PubMed ID: 16787387

Title: Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids.

PubMed ID: 16787387

DOI: 10.1042/bj20051988

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 6374651

Title: Human liver alcohol dehydrogenase: amino acid substitution in the beta 2 beta 2 Oriental isozyme explains functional properties, establishes an active site structure, and parallels mutational exchanges in the yeast enzyme.

PubMed ID: 6374651

DOI: 10.1073/pnas.81.10.3024

PubMed ID: 3619918

Title: The human beta 3 alcohol dehydrogenase subunit differs from beta 1 by a Cys for Arg-369 substitution which decreases NAD(H) binding.

PubMed ID: 3619918

DOI: 10.1016/0006-291x(87)90779-0

PubMed ID: 1896463

Title: Structure of human beta 1 beta 1 alcohol dehydrogenase: catalytic effects of non-active-site substitutions.

PubMed ID: 1896463

DOI: 10.1073/pnas.88.18.8149

PubMed ID: 8201622

Title: Structures of three human beta alcohol dehydrogenase variants. Correlations with their functional differences.

PubMed ID: 8201622

DOI: 10.1006/jmbi.1994.1382

PubMed ID: 8663387

Title: X-ray structure of human beta3beta3 alcohol dehydrogenase. The contribution of ionic interactions to coenzyme binding.

PubMed ID: 8663387

DOI: 10.1074/jbc.271.29.17057

PubMed ID: 11274460

Title: Three-dimensional structures of the three human class I alcohol dehydrogenases.

PubMed ID: 11274460

DOI: 10.1110/ps.45001

PubMed ID: 10733556

Title: Genetic polymorphism of alcohol dehydrogenase in Europeans: the ADH2*2 allele decreases the risk for alcoholism and is associated with ADH3*1.

PubMed ID: 10733556

DOI: 10.1053/he.2000.5978

Sequence Information:

  • Length: 375
  • Mass: 39835
  • Checksum: 2C5104F834950B1A
  • Sequence:
    • MSTAGKVIKC KAAVLWEVKK PFSIEDVEVA PPKAYEVRIK MVAVGICHTD DHVVSGNLVT 
PLPVILGHEA AGIVESVGEG VTTVKPGDKV IPLFTPQCGK CRVCKNPESN YCLKNDLGNP 
RGTLQDGTRR FTCRGKPIHH FLGTSTFSQY TVVDENAVAK IDAASPLEKV CLIGCGFSTG 
YGSAVNVAKV TPGSTCAVFG LGGVGLSAVM GCKAAGAARI IAVDINKDKF AKAKELGATE 
CINPQDYKKP IQEVLKEMTD GGVDFSFEVI GRLDTMMASL LCCHEACGTS VIVGVPPASQ 
NLSINPMLLL TGRTWKGAVY GGFKSKEGIP KLVADFMAKK FSLDALITHV LPFEKINEGF 
DLLHSGKSIR TVLTF

Genular Protein ID: 2405567327

Symbol: D6RHZ6_HUMAN

Name: N/A

UniProtKB Accession Codes:

D6RHZ6 A0A0D9SFH8

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 3 ExpressionAtlas 1 GO 5 Gene3D 2 HGNC 1 InterPro 5 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 4 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 335
  • Mass: 35393
  • Checksum: EC18CCAAE3CEC385
  • Sequence:
    • MVAVGICHTD DHVVSGNLVT PLPVILGHEA AGIVESVGEG VTTVKPGDKV IPLFTPQCGK 
CRVCKNPESN YCLKNDLGNP RGTLQDGTRR FTCRGKPIHH FLGTSTFSQY TVVDENAVAK 
IDAASPLEKV CLIGCGFSTG YGSAVNVAKV TPGSTCAVFG LGGVGLSAVM GCKAAGAARI 
IAVDINKDKF AKAKELGATE CINPQDYKKP IQEVLKEMTD GGVDFSFEVI GRLDTMMASL 
LCCHEACGTS VIVGVPPASQ NLSINPMLLL TGRTWKGAVY GGFKSKEGIP KLVADFMAKK 
FSLDALITHV LPFEKINEGF DLLHSGKSIR TVLTF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.