Details for: ADH1B
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 6
Marker Score: 2,915 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 3.94
Marker Score: 2,594 - Cell Name: subcutaneous fat cell (CL0002521)
Fold Change: 3.91
Marker Score: 1,429 - Cell Name: fat cell (CL0000136)
Fold Change: 3.41
Marker Score: 1,905 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 3.21
Marker Score: 8,403 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 2.8
Marker Score: 15,055 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 2.7
Marker Score: 1,239 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 2.58
Marker Score: 1,437 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 2.2
Marker Score: 14,172 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 2.07
Marker Score: 8,912 - Cell Name: keratocyte (CL0002363)
Fold Change: 1.98
Marker Score: 456 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.74
Marker Score: 3,348 - Cell Name: adventitial cell (CL0002503)
Fold Change: 1.65
Marker Score: 407 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.6
Marker Score: 1,162 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 1.52
Marker Score: 1,633 - Cell Name: mural cell (CL0008034)
Fold Change: 1.48
Marker Score: 169,979 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.42
Marker Score: 1,417 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 1.36
Marker Score: 864 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.25
Marker Score: 849 - Cell Name: muscle cell (CL0000187)
Fold Change: 1.25
Marker Score: 353 - Cell Name: inflammatory cell (CL0009002)
Fold Change: 1.14
Marker Score: 491 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.05
Marker Score: 6,337 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 1.03
Marker Score: 790 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 1.01
Marker Score: 1,555 - Cell Name: inflammatory macrophage (CL0000863)
Fold Change: 1.01
Marker Score: 312 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,814 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,039 - Cell Name: blood vessel smooth muscle cell (CL0019018)
Fold Change: 1
Marker Score: 262 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,407 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.98
Marker Score: 503 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.97
Marker Score: 457 - Cell Name: adipose microvascular endothelial cell (CL2000072)
Fold Change: 0.97
Marker Score: 287 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 0.95
Marker Score: 953 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,412 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.93
Marker Score: 5,298 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.93
Marker Score: 349 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.92
Marker Score: 370 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,740 - Cell Name: fibroblast (CL0000057)
Fold Change: 0.91
Marker Score: 881 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.91
Marker Score: 377 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9
Marker Score: 323 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.89
Marker Score: 30,387 - Cell Name: reticular cell (CL0000432)
Fold Change: 0.87
Marker Score: 319 - Cell Name: tracheobronchial smooth muscle cell (CL0019019)
Fold Change: 0.82
Marker Score: 240 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 0.82
Marker Score: 212 - Cell Name: mesenchymal lymphangioblast (CL0005021)
Fold Change: 0.81
Marker Score: 182 - Cell Name: mesothelial cell (CL0000077)
Fold Change: 0.81
Marker Score: 326 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.77
Marker Score: 1,256 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 0.77
Marker Score: 950 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 393 - Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 0.75
Marker Score: 197 - Cell Name: brush cell (CL0002204)
Fold Change: 0.75
Marker Score: 683 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.74
Marker Score: 856 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.74
Marker Score: 3,111 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: 0.73
Marker Score: 202 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.69
Marker Score: 177 - Cell Name: bronchial smooth muscle cell (CL0002598)
Fold Change: 0.65
Marker Score: 185 - Cell Name: theca cell (CL0000503)
Fold Change: 0.65
Marker Score: 463 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.62
Marker Score: 9,928 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.62
Marker Score: 135 - Cell Name: tracheal goblet cell (CL1000329)
Fold Change: 0.6
Marker Score: 1,705 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.59
Marker Score: 563 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.59
Marker Score: 388 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.58
Marker Score: 373 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.58
Marker Score: 151 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.56
Marker Score: 444 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.55
Marker Score: 147 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.55
Marker Score: 230 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.54
Marker Score: 3,265 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 0.53
Marker Score: 6,953 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.5
Marker Score: 188 - Cell Name: stromal cell (CL0000499)
Fold Change: 0.49
Marker Score: 576 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 0.49
Marker Score: 280 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 0.48
Marker Score: 344 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 0.46
Marker Score: 570 - Cell Name: contractile cell (CL0000183)
Fold Change: 0.45
Marker Score: 245 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 0.44
Marker Score: 292 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.44
Marker Score: 300 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 0.41
Marker Score: 1,708 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.4
Marker Score: 255 - Cell Name: endothelial cell (CL0000115)
Fold Change: 0.4
Marker Score: 362 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.39
Marker Score: 124 - Cell Name: mucosal invariant T cell (CL0000940)
Fold Change: 0.39
Marker Score: 344 - Cell Name: tendon cell (CL0000388)
Fold Change: 0.38
Marker Score: 94 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 0.37
Marker Score: 118 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.37
Marker Score: 368 - Cell Name: pericyte (CL0000669)
Fold Change: 0.36
Marker Score: 208 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.33
Marker Score: 5,111 - Cell Name: chondrocyte (CL0000138)
Fold Change: 0.32
Marker Score: 146 - Cell Name: bronchus fibroblast of lung (CL2000093)
Fold Change: 0.32
Marker Score: 445 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.32
Marker Score: 1,382 - Cell Name: myeloid cell (CL0000763)
Fold Change: 0.31
Marker Score: 500 - Cell Name: precursor cell (CL0011115)
Fold Change: 0.31
Marker Score: 75 - Cell Name: secretory cell (CL0000151)
Fold Change: 0.28
Marker Score: 517 - Cell Name: Unknown (CL0000003)
Fold Change: 0.27
Marker Score: 843 - Cell Name: neural cell (CL0002319)
Fold Change: 0.26
Marker Score: 127 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.26
Marker Score: 157 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.26
Marker Score: 520 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.24
Marker Score: 3,258 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 0.24
Marker Score: 858
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1850908328
Symbol: ADH1B_HUMAN
Name: Alcohol dehydrogenase 1B
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2986130
Title: Molecular cloning of a full-length cDNA for human alcohol dehydrogenase.
PubMed ID: 2986130
PubMed ID: 3000832
Title: cDNA clones coding for the beta-subunit of human liver alcohol dehydrogenase have differently sized 3'-non-coding regions.
PubMed ID: 3000832
PubMed ID: 2935533
Title: Molecular analysis of the human class I alcohol dehydrogenase gene family and nucleotide sequence of the gene encoding the beta subunit.
PubMed ID: 2935533
PubMed ID: 2935875
Title: Three human alcohol dehydrogenase subunits: cDNA structure and molecular and evolutionary divergence.
PubMed ID: 2935875
PubMed ID: 2679216
Title: Nucleotide sequence of the ADH2(3) gene encoding the human alcohol dehydrogenase beta 3 subunit.
PubMed ID: 2679216
PubMed ID: 2547609
Title: The genes for human alcohol dehydrogenases beta 1 and beta 2 differ by only one nucleotide.
PubMed ID: 2547609
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 6391920
Title: Human liver alcohol dehydrogenase. 1. The primary structure of the beta 1 beta 1 isoenzyme.
PubMed ID: 6391920
PubMed ID: 3397059
Title: Genotyping of human alcohol dehydrogenases at the ADH2 and ADH3 loci following DNA sequence amplification.
PubMed ID: 3397059
PubMed ID: 15369820
Title: Kinetics of human alcohol dehydrogenase with ring-oxidized retinoids: effect of Tween 80.
PubMed ID: 15369820
PubMed ID: 16787387
Title: Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids.
PubMed ID: 16787387
DOI: 10.1042/bj20051988
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 6374651
Title: Human liver alcohol dehydrogenase: amino acid substitution in the beta 2 beta 2 Oriental isozyme explains functional properties, establishes an active site structure, and parallels mutational exchanges in the yeast enzyme.
PubMed ID: 6374651
PubMed ID: 3619918
Title: The human beta 3 alcohol dehydrogenase subunit differs from beta 1 by a Cys for Arg-369 substitution which decreases NAD(H) binding.
PubMed ID: 3619918
PubMed ID: 1896463
Title: Structure of human beta 1 beta 1 alcohol dehydrogenase: catalytic effects of non-active-site substitutions.
PubMed ID: 1896463
PubMed ID: 8201622
Title: Structures of three human beta alcohol dehydrogenase variants. Correlations with their functional differences.
PubMed ID: 8201622
PubMed ID: 8663387
Title: X-ray structure of human beta3beta3 alcohol dehydrogenase. The contribution of ionic interactions to coenzyme binding.
PubMed ID: 8663387
PubMed ID: 11274460
Title: Three-dimensional structures of the three human class I alcohol dehydrogenases.
PubMed ID: 11274460
DOI: 10.1110/ps.45001
PubMed ID: 10733556
Title: Genetic polymorphism of alcohol dehydrogenase in Europeans: the ADH2*2 allele decreases the risk for alcoholism and is associated with ADH3*1.
PubMed ID: 10733556
DOI: 10.1053/he.2000.5978
Sequence Information:
- Length: 375
- Mass: 39835
- Checksum: 2C5104F834950B1A
- Sequence:
MSTAGKVIKC KAAVLWEVKK PFSIEDVEVA PPKAYEVRIK MVAVGICHTD DHVVSGNLVT PLPVILGHEA AGIVESVGEG VTTVKPGDKV IPLFTPQCGK CRVCKNPESN YCLKNDLGNP RGTLQDGTRR FTCRGKPIHH FLGTSTFSQY TVVDENAVAK IDAASPLEKV CLIGCGFSTG YGSAVNVAKV TPGSTCAVFG LGGVGLSAVM GCKAAGAARI IAVDINKDKF AKAKELGATE CINPQDYKKP IQEVLKEMTD GGVDFSFEVI GRLDTMMASL LCCHEACGTS VIVGVPPASQ NLSINPMLLL TGRTWKGAVY GGFKSKEGIP KLVADFMAKK FSLDALITHV LPFEKINEGF DLLHSGKSIR TVLTF
Genular Protein ID: 2405567327
Symbol: D6RHZ6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 335
- Mass: 35393
- Checksum: EC18CCAAE3CEC385
- Sequence:
MVAVGICHTD DHVVSGNLVT PLPVILGHEA AGIVESVGEG VTTVKPGDKV IPLFTPQCGK CRVCKNPESN YCLKNDLGNP RGTLQDGTRR FTCRGKPIHH FLGTSTFSQY TVVDENAVAK IDAASPLEKV CLIGCGFSTG YGSAVNVAKV TPGSTCAVFG LGGVGLSAVM GCKAAGAARI IAVDINKDKF AKAKELGATE CINPQDYKKP IQEVLKEMTD GGVDFSFEVI GRLDTMMASL LCCHEACGTS VIVGVPPASQ NLSINPMLLL TGRTWKGAVY GGFKSKEGIP KLVADFMAKK FSLDALITHV LPFEKINEGF DLLHSGKSIR TVLTF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.