Details for: ADH1B

Gene ID: 125

Symbol: ADH1B

Ensembl ID: ENSG00000196616

Description: alcohol dehydrogenase 1B (class I), beta polypeptide

Associated with

Other Information

Genular Protein ID: 1850908328

Symbol: ADH1B_HUMAN

Name: Alcohol dehydrogenase 1B

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2986130

Title: Molecular cloning of a full-length cDNA for human alcohol dehydrogenase.

PubMed ID: 2986130

DOI: 10.1073/pnas.82.9.2703

PubMed ID: 3000832

Title: cDNA clones coding for the beta-subunit of human liver alcohol dehydrogenase have differently sized 3'-non-coding regions.

PubMed ID: 3000832

DOI: 10.1016/0014-5793(86)80111-9

PubMed ID: 2935533

Title: Molecular analysis of the human class I alcohol dehydrogenase gene family and nucleotide sequence of the gene encoding the beta subunit.

PubMed ID: 2935533

DOI: 10.1016/s0021-9258(17)35892-1

PubMed ID: 2935875

Title: Three human alcohol dehydrogenase subunits: cDNA structure and molecular and evolutionary divergence.

PubMed ID: 2935875

DOI: 10.1073/pnas.83.3.634

PubMed ID: 2679216

Title: Nucleotide sequence of the ADH2(3) gene encoding the human alcohol dehydrogenase beta 3 subunit.

PubMed ID: 2679216

DOI: 10.1111/j.1530-0277.1989.tb00383.x

PubMed ID: 2547609

Title: The genes for human alcohol dehydrogenases beta 1 and beta 2 differ by only one nucleotide.

PubMed ID: 2547609

DOI: 10.1111/j.1432-1033.1989.tb14931.x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6391920

Title: Human liver alcohol dehydrogenase. 1. The primary structure of the beta 1 beta 1 isoenzyme.

PubMed ID: 6391920

DOI: 10.1111/j.1432-1033.1984.tb08573.x

PubMed ID: 3397059

Title: Genotyping of human alcohol dehydrogenases at the ADH2 and ADH3 loci following DNA sequence amplification.

PubMed ID: 3397059

DOI: 10.1016/0888-7543(88)90004-3

PubMed ID: 15369820

Title: Kinetics of human alcohol dehydrogenase with ring-oxidized retinoids: effect of Tween 80.

PubMed ID: 15369820

DOI: 10.1016/j.abb.2004.07.002

PubMed ID: 16787387

Title: Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids.

PubMed ID: 16787387

DOI: 10.1042/bj20051988

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 6374651

Title: Human liver alcohol dehydrogenase: amino acid substitution in the beta 2 beta 2 Oriental isozyme explains functional properties, establishes an active site structure, and parallels mutational exchanges in the yeast enzyme.

PubMed ID: 6374651

DOI: 10.1073/pnas.81.10.3024

PubMed ID: 3619918

Title: The human beta 3 alcohol dehydrogenase subunit differs from beta 1 by a Cys for Arg-369 substitution which decreases NAD(H) binding.

PubMed ID: 3619918

DOI: 10.1016/0006-291x(87)90779-0

PubMed ID: 1896463

Title: Structure of human beta 1 beta 1 alcohol dehydrogenase: catalytic effects of non-active-site substitutions.

PubMed ID: 1896463

DOI: 10.1073/pnas.88.18.8149

PubMed ID: 8201622

Title: Structures of three human beta alcohol dehydrogenase variants. Correlations with their functional differences.

PubMed ID: 8201622

DOI: 10.1006/jmbi.1994.1382

PubMed ID: 8663387

Title: X-ray structure of human beta3beta3 alcohol dehydrogenase. The contribution of ionic interactions to coenzyme binding.

PubMed ID: 8663387

DOI: 10.1074/jbc.271.29.17057

PubMed ID: 11274460

Title: Three-dimensional structures of the three human class I alcohol dehydrogenases.

PubMed ID: 11274460

DOI: 10.1110/ps.45001

PubMed ID: 10733556

Title: Genetic polymorphism of alcohol dehydrogenase in Europeans: the ADH2*2 allele decreases the risk for alcoholism and is associated with ADH3*1.

PubMed ID: 10733556

DOI: 10.1053/he.2000.5978

Sequence Information:

  • Length: 375
  • Mass: 39835
  • Checksum: 2C5104F834950B1A
  • Sequence:
  • MSTAGKVIKC KAAVLWEVKK PFSIEDVEVA PPKAYEVRIK MVAVGICHTD DHVVSGNLVT 
    PLPVILGHEA AGIVESVGEG VTTVKPGDKV IPLFTPQCGK CRVCKNPESN YCLKNDLGNP 
    RGTLQDGTRR FTCRGKPIHH FLGTSTFSQY TVVDENAVAK IDAASPLEKV CLIGCGFSTG 
    YGSAVNVAKV TPGSTCAVFG LGGVGLSAVM GCKAAGAARI IAVDINKDKF AKAKELGATE 
    CINPQDYKKP IQEVLKEMTD GGVDFSFEVI GRLDTMMASL LCCHEACGTS VIVGVPPASQ 
    NLSINPMLLL TGRTWKGAVY GGFKSKEGIP KLVADFMAKK FSLDALITHV LPFEKINEGF 
    DLLHSGKSIR TVLTF

Genular Protein ID: 2405567327

Symbol: D6RHZ6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 335
  • Mass: 35393
  • Checksum: EC18CCAAE3CEC385
  • Sequence:
  • MVAVGICHTD DHVVSGNLVT PLPVILGHEA AGIVESVGEG VTTVKPGDKV IPLFTPQCGK 
    CRVCKNPESN YCLKNDLGNP RGTLQDGTRR FTCRGKPIHH FLGTSTFSQY TVVDENAVAK 
    IDAASPLEKV CLIGCGFSTG YGSAVNVAKV TPGSTCAVFG LGGVGLSAVM GCKAAGAARI 
    IAVDINKDKF AKAKELGATE CINPQDYKKP IQEVLKEMTD GGVDFSFEVI GRLDTMMASL 
    LCCHEACGTS VIVGVPPASQ NLSINPMLLL TGRTWKGAVY GGFKSKEGIP KLVADFMAKK 
    FSLDALITHV LPFEKINEGF DLLHSGKSIR TVLTF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.