Genular: Defining Cellular Identity and Function

Details for: Cd3g

Gene ID: 12502

Symbol: Cd3g

Ensembl ID: ENSMUSG00000002033

Description: CD3 antigen, gamma polypeptide

Associated with

Adaptive immune system
(R-MMU-1280218)
Cargo recognition for clathrin-mediated endocytosis
(R-MMU-8856825)
Clathrin-mediated endocytosis
(R-MMU-8856828)
Costimulation by the cd28 family
(R-MMU-388841)
Downstream tcr signaling
(R-MMU-202424)
Fcgamma receptor (fcgr) dependent phagocytosis
(R-MMU-2029480)
Fcgr activation
(R-MMU-2029481)
Generation of second messenger molecules
(R-MMU-202433)
Immune system
(R-MMU-168256)
Immunoregulatory interactions between a lymphoid and a non-lymphoid cell
(R-MMU-198933)
Innate immune system
(R-MMU-168249)
Membrane trafficking
(R-MMU-199991)
Pd-1 signaling
(R-MMU-389948)
Phosphorylation of cd3 and tcr zeta chains
(R-MMU-202427)
Regulation of actin dynamics for phagocytic cup formation
(R-MMU-2029482)
Role of phospholipids in phagocytosis
(R-MMU-2029485)
Tcr signaling
(R-MMU-202403)
Translocation of zap-70 to immunological synapse
(R-MMU-202430)
Vesicle-mediated transport
(R-MMU-5653656)
Adaptive immune response
(GO:0002250)
Alpha-beta t cell receptor complex
(GO:0042105)
Cell surface receptor signaling pathway
(GO:0007166)
Cytosol
(GO:0005829)
Establishment or maintenance of cell polarity
(GO:0007163)
External side of plasma membrane
(GO:0009897)
Identical protein binding
(GO:0042802)
Immune system process
(GO:0002376)
Membrane
(GO:0016020)
Plasma membrane
(GO:0005886)
Positive thymic t cell selection
(GO:0045059)
Protein transport
(GO:0015031)
Regulation of lymphocyte apoptotic process
(GO:0070228)
Transmembrane signaling receptor activity
(GO:0004888)

Other Information

Proteins

T-cell surface glycoprotein CD3 gamma chain

Genular Protein ID: 2280491457

Symbol: CD3G_MOUSE

Name: T-cell surface glycoprotein CD3 gamma chain

UniProtKB Accession Codes:

P11942

Database IDs:

Citations:

PubMed ID: 3655657

Title: Cloning and sequencing of murine T3 gamma cDNA from a subtractive cDNA library.

PubMed ID: 3655657

DOI: 10.1084/jem.166.4.1186

PubMed ID: 2952720

Title: Molecular cloning of the cDNA encoding the T3 gamma subunit of the mouse T3/T cell antigen receptor complex.

PubMed ID: 2952720

PubMed ID: 2827170

Title: Close linkage of the mouse and human CD3 gamma- and delta-chain genes suggests that their transcription is controlled by common regulatory elements.

PubMed ID: 2827170

DOI: 10.1073/pnas.84.24.9131

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9524111

Title: The CD3gamma chain is essential for development of both the TCRalphabeta and TCRgammadelta lineages.

PubMed ID: 9524111

DOI: 10.1093/emboj/17.7.1871

PubMed ID: 25920998

Title: Fine-tuning of T-cell development by the CD3gamma di-leucine-based TCR-sorting motif.

PubMed ID: 25920998

DOI: 10.1093/intimm/dxv022

Sequence Information:

Length: 182
Mass: 20234
Checksum: 7F9D8D44A5C360D5
Sequence:

MEQRKGLAGL FLVISLLQGT VAQTNKAKNL VQVDGSRGDG SVLLTCGLTD KTIKWLKDGS 
IISPLNATKN TWNLGNNAKD PRGTYQCQGA KETSNPLQVY YRMCENCIEL NIGTISGFIF 
AEVISIFFLA LGVYLIAGQD GVRQSRASDK QTLLQNEQLY QPLKDREYDQ YSHLQGNQLR 
KK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cd3g

Associated with

Other Information

Cloning and sequencing of murine T3 gamma cDNA from a subtractive cDNA library. PubMed ID: 3655657

Molecular cloning of the cDNA encoding the T3 gamma subunit of the mouse T3/T cell antigen receptor complex. PubMed ID: 2952720

Close linkage of the mouse and human CD3 gamma- and delta-chain genes suggests that their transcription is controlled by common regulatory elements. PubMed ID: 2827170

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The CD3gamma chain is essential for development of both the TCRalphabeta and TCRgammadelta lineages. PubMed ID: 9524111