Details for: Cd68

Gene ID: 12514

Symbol: Cd68

Ensembl ID: ENSMUSG00000018774

Description: CD68 antigen

Associated with

Other Information

Genular Protein ID: 2114660253

Symbol: CD68_MOUSE

Name: Macrosialin

UniProtKB Accession Codes:

P31996 O54688 O70321 Q3S4A9 Q5F2A8 Q9DD15

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 DNASU 1 EMBL 10 Ensembl 1 ExpressionAtlas 1 GO 12 Gene3D 1 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 3 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SAM 1 SMR 1 STRING 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8486654

Title: Macrosialin, a mouse macrophage-restricted glycoprotein, is a member of the lamp/lgp family.

PubMed ID: 8486654

DOI: 10.1016/s0021-9258(18)98400-0

PubMed ID: 9653646

Title: Structure, organization, and chromosomal mapping of the gene encoding macrosialin, a macrophage-restricted protein.

PubMed ID: 9653646

DOI: 10.1006/geno.1998.5327

PubMed ID: 9806844

Title: Functional comparison of the murine macrosialin and human CD68 promoters in macrophage and nonmacrophage cell lines.

PubMed ID: 9806844

DOI: 10.1006/geno.1998.5546

PubMed ID: 9479000

Title: The macrosialin promoter directs high levels of transcriptional activity in macrophages dependent on combinatorial interactions between PU.1 and c-Jun.

PubMed ID: 9479000

DOI: 10.1074/jbc.273.9.5389

PubMed ID: 10524236

Title: Five different genes, Eif4a1, Cd68, Supl15h, Sox15 and Fxr2h, are clustered in a 40 kb region of mouse chromosome 11.

PubMed ID: 10524236

DOI: 10.1016/s0378-1119(99)00301-7

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16521125

Title: Influence of caloric restriction on motor behavior, longevity, and brain lipid composition in Sandhoff disease mice.

PubMed ID: 16521125

DOI: 10.1002/jnr.20798

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 326
  • Mass: 34818
  • Checksum: AB7203A9A7EA47BA
  • Sequence:
    • MRLPVCLILL GPLIAQGTEE DCPHKKAVTL LPSFTMTPTA TESTASPTTS HRPTTTSHGN 
VTVHTSSGPT TVTHNPATTT SHGNATISHA TVSPTTNGTA TSPRSSTVGP HPGPPPPSPS 
PRSKGALGNY TWANGSQPCV QLQAQIQIRI LYPIQGGRKA WGISVLNPNK TKVQGGCDGT 
HPHLSLSFPY GQLTFGFKQD LHQSPSTVYL DYMAVEYNVS FPQAAQWTFM AQNSSLRELQ 
APLGQSFCCG NASIVLSPAV HLDLLSLRLQ AAQLPDKGHF GPCFSCNRDQ SLLLPLIIGL 
VLLGLLTLVL IAFCITRRRQ STYQPL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.