Details for: Cd79a
Associated with
Other Information
Genular Protein ID: 902439424
Symbol: CD79A_MOUSE
Name: B-cell antigen receptor complex-associated protein alpha chain
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2463161
Title: B lymphocyte lineage-restricted expression of mb-1, a gene with CD3-like structural properties.
PubMed ID: 2463161
PubMed ID: 2358676
Title: Structure of the murine mb-1 gene encoding a putative sIgM-associated molecule.
PubMed ID: 2358676
PubMed ID: 1639443
Title: Molecular cloning of the Ig-alpha subunit of the human B-cell antigen receptor complex.
PubMed ID: 1639443
DOI: 10.1007/bf00215058
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1922076
Title: Heterogeneously initiated transcription from the pre-B- and B-cell-specific mb-1 promoter: analysis of the requirement for upstream factor-binding sites and initiation site sequences.
PubMed ID: 1922076
PubMed ID: 2269334
Title: Identification of the genes encoding the IgM-alpha and Ig-beta components of the IgM antigen receptor complex by amino-terminal sequencing.
PubMed ID: 2269334
PubMed ID: 2023945
Title: IgM antigen receptor complex contains phosphoprotein products of B29 and mb-1 genes.
PubMed ID: 2023945
PubMed ID: 1506682
Title: The MB-1/B29 heterodimer couples the B cell antigen receptor to multiple src family protein tyrosine kinases.
PubMed ID: 1506682
PubMed ID: 15335855
Title: B-cell antigen receptor motifs have redundant signalling capabilities and bind the tyrosine kinases PTK72, Lyn and Fyn.
PubMed ID: 15335855
PubMed ID: 8306975
Title: Dual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptor.
PubMed ID: 8306975
PubMed ID: 8168489
Title: Analysis of Ig-alpha-tyrosine kinase interaction reveals two levels of binding specificity and tyrosine phosphorylated Ig-alpha stimulation of Fyn activity.
PubMed ID: 8168489
PubMed ID: 8175787
Title: Activation of B- and T-cells by the cytoplasmic domains of the B-cell antigen receptor proteins Ig-alpha and Ig-beta.
PubMed ID: 8175787
PubMed ID: 7538118
Title: Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation.
PubMed ID: 7538118
PubMed ID: 7592958
Title: Reconstitution of the B cell antigen receptor signaling components in COS cells.
PubMed ID: 7592958
PubMed ID: 8976175
Title: The two membrane isoforms of human IgE assemble into functionally distinct B cell antigen receptors.
PubMed ID: 8976175
PubMed ID: 9469435
Title: A tyrosine-based signal present in Ig alpha mediates B cell receptor constitutive internalization.
PubMed ID: 9469435
PubMed ID: 10591178
Title: A negative regulatory role for Ig-alpha during B cell development.
PubMed ID: 10591178
PubMed ID: 10587346
Title: A role for lipid rafts in B cell antigen receptor signaling and antigen targeting.
PubMed ID: 10587346
PubMed ID: 10352267
Title: Ig alpha and Ig beta are required for efficient trafficking to late endosomes and to enhance antigen presentation.
PubMed ID: 10352267
PubMed ID: 11449366
Title: Association of SLP-65/BLNK with the B cell antigen receptor through a non-ITAM tyrosine of Ig-alpha.
PubMed ID: 11449366
DOI: 10.1002/1521-4141(200107)31:7<2126::aid-immu2126>3.0.co;2-o
PubMed ID: 11514602
Title: Interference with immunoglobulin (Ig)alpha immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igbeta cytoplasmic tail.
PubMed ID: 11514602
PubMed ID: 11238609
Title: Translocation of the B cell antigen receptor into lipid rafts reveals a novel step in signaling.
PubMed ID: 11238609
PubMed ID: 12356683
Title: Cooperative interaction of Ig(alpha) and Ig(beta) of the BCR regulates the kinetics and specificity of antigen targeting.
PubMed ID: 12356683
PubMed ID: 11859098
Title: Receptor-facilitated antigen presentation requires the recruitment of B cell linker protein to Igalpha.
PubMed ID: 11859098
PubMed ID: 12097390
Title: B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta.
PubMed ID: 12097390
PubMed ID: 11909947
Title: The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways.
PubMed ID: 11909947
PubMed ID: 15661879
Title: Ig alpha/Ig beta complexes generate signals for B cell development independent of selective plasma membrane compartmentalization.
PubMed ID: 15661879
PubMed ID: 16860757
Title: The B cell receptor promotes B cell activation and proliferation through a non-ITAM tyrosine in the Igalpha cytoplasmic domain.
PubMed ID: 16860757
PubMed ID: 17163454
Title: The Ig-alpha ITAM is required for efficient differentiation but not proliferation of pre-B cells.
PubMed ID: 17163454
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 20231378
Title: Arginine methylation of the B cell antigen receptor promotes differentiation.
PubMed ID: 20231378
DOI: 10.1084/jem.20091303
Sequence Information:
- Length: 220
- Mass: 24583
- Checksum: A4C648C2BE6D3E38
- Sequence:
MPGGLEALRA LPLLLFLSYA CLGPGCQALR VEGGPPSLTV NLGEEARLTC ENNGRNPNIT WWFSLQSNIT WPPVPLGPGQ GTTGQLFFPE VNKNHRGLYW CQVIENNILK RSCGTYLRVR NPVPRPFLDM GEGTKNRIIT AEGIILLFCA VVPGTLLLFR KRWQNEKFGV DMPDDYEDEN LYEGLNLDDC SMYEDISRGL QGTYQDVGNL HIGDAQLEKP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.