Genular: Defining Cellular Identity and Function

Details for: Cd80

Gene ID: 12519

Symbol: Cd80

Ensembl ID: ENSMUSG00000075122

Description: CD80 antigen

Associated with

Adaptive immune system
(R-MMU-1280218)
Cd28 co-stimulation
(R-MMU-389356)
Cd28 dependent pi3k/akt signaling
(R-MMU-389357)
Cd28 dependent vav1 pathway
(R-MMU-389359)
Costimulation by the cd28 family
(R-MMU-388841)
Ctla4 inhibitory signaling
(R-MMU-389513)
Immune system
(R-MMU-168256)
Intracellular signaling by second messengers
(R-MMU-9006925)
Negative regulation of the pi3k/akt network
(R-MMU-199418)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-MMU-6811558)
Pip3 activates akt signaling
(R-MMU-1257604)
Signal transduction
(R-MMU-162582)
Cell surface
(GO:0009986)
Cell surface receptor signaling pathway
(GO:0007166)
Cellular response to lipopolysaccharide
(GO:0071222)
Coreceptor activity
(GO:0015026)
External side of plasma membrane
(GO:0009897)
Immune response
(GO:0006955)
Membrane
(GO:0016020)
Negative regulation of t cell mediated immunity
(GO:0002710)
Negative regulation of t cell proliferation
(GO:0042130)
Positive regulation of alpha-beta t cell proliferation
(GO:0046641)
Positive regulation of peptidyl-tyrosine phosphorylation
(GO:0050731)
Positive regulation of t cell proliferation
(GO:0042102)
Protein binding
(GO:0005515)
Protein complex involved in cell adhesion
(GO:0098636)
Receptor ligand activity
(GO:0048018)
T cell activation
(GO:0042110)
T cell costimulation
(GO:0031295)

Other Information

Proteins

T-lymphocyte activation antigen CD80

Genular Protein ID: 2030561203

Symbol: CD80_MOUSE

Name: T-lymphocyte activation antigen CD80

UniProtKB Accession Codes:

Q00609 Q61332

Database IDs:

Citations:

PubMed ID: 1714935

Title: Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7.

PubMed ID: 1714935

DOI: 10.1084/jem.174.3.625

PubMed ID: 7686531

Title: Genomic organization of the mouse B-lymphocyte activation antigen B7.

PubMed ID: 7686531

DOI: 10.1007/bf00188807

PubMed ID: 7513163

Title: Identification of an alternatively spliced form of the murine homologue of B7.

PubMed ID: 7513163

DOI: 10.1006/bbrc.1994.1469

PubMed ID: 19656770

Title: The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.

PubMed ID: 19656770

DOI: 10.1074/mcp.m900195-mcp200

Sequence Information:

Length: 306
Mass: 34590
Checksum: 1DBADE0931B84C62
Sequence:

MACNCQLMQD TPLLKFPCPR LILLFVLLIR LSQVSSDVDE QLSKSVKDKV LLPCRYNSPH 
EDESEDRIYW QKHDKVVLSV IAGKLKVWPE YKNRTLYDNT TYSLIILGLV LSDRGTYSCV 
VQKKERGTYE VKHLALVKLS IKADFSTPNI TESGNPSADT KRITCFASGG FPKPRFSWLE 
NGRELPGINT TISQDPESEL YTISSQLDFN TTRNHTIKCL IKYGDAHVSE DFTWEKPPED 
PPDSKNTLVL FGAGFGAVIT VVVIVVIIKC FCKHRSCFRR NEASRETNNS LTFGPEEALA 
EQTVFL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cd80

Associated with

Other Information

Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7. PubMed ID: 1714935

Genomic organization of the mouse B-lymphocyte activation antigen B7. PubMed ID: 7686531

Identification of an alternatively spliced form of the murine homologue of B7. PubMed ID: 7513163

The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation. PubMed ID: 19656770

Database document:

PubMed ID: 1714935

PubMed ID: 7686531

PubMed ID: 7513163

PubMed ID: 19656770