Details for: Cd8b1

Gene ID: 12526

Symbol: Cd8b1

Ensembl ID: ENSMUSG00000053044

Description: CD8 subunit beta 1

Associated with

Other Information

Genular Protein ID: 242826037

Symbol: CD8B_MOUSE

Name: T-cell surface glycoprotein CD8 beta chain

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2452747

Title: Gene transfer of the Ly-3 chain gene of the mouse CD8 molecular complex: co-transfer with the Ly-2 polypeptide gene results in detectable cell surface expression of the Ly-3 antigenic determinants.

PubMed ID: 2452747

DOI: 10.1002/eji.1830180419

PubMed ID: 3258885

Title: Molecular linkage of the Ly-3 and Ly-2 genes. Requirement of Ly-2 for Ly-3 surface expression.

PubMed ID: 3258885

PubMed ID: 2784466

Title: Isolation and characterization of the mouse CD8 beta-chain (Ly-3) genes. Absence of an intervening sequence between V- and J-like gene segments.

PubMed ID: 2784466

PubMed ID: 3035575

Title: Molecular cloning of Lyt-3, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to immunoglobulin and T-cell receptor variable and joining regions.

PubMed ID: 3035575

DOI: 10.1073/pnas.84.12.4210

PubMed ID: 3498943

Title: Molecular characterization of the murine cytotoxic T-cell membrane glycoprotein Ly-3 (CD8).

PubMed ID: 3498943

DOI: 10.1073/pnas.84.19.6874

PubMed ID: 8537123

Title: Autoimmune diabetes-prone NOD mice express the Lyt2 alpha (Lyt2.1) and Lyt3 alpha (Lyt3.1) alleles of CD8.

PubMed ID: 8537123

DOI: 10.1007/bf00186598

PubMed ID: 3169881

Title: Structure and expression of the Lyt-3a gene of C.AKR mice.

PubMed ID: 3169881

DOI: 10.1007/bf00364234

PubMed ID: 8108731

Title: Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.

PubMed ID: 8108731

DOI: 10.1126/science.8108731

PubMed ID: 8064243

Title: Reduced thymic maturation but normal effector function of CD8+ T cells in CD8 beta gene-targeted mice.

PubMed ID: 8064243

DOI: 10.1084/jem.180.3.959

PubMed ID: 12215456

Title: CD3 delta establishes a functional link between the T cell receptor and CD8.

PubMed ID: 12215456

DOI: 10.1074/jbc.m208119200

PubMed ID: 19088062

Title: CD8beta knockout mice mount normal anti-viral CD8+ T cell responses -- but why?

PubMed ID: 19088062

DOI: 10.1093/intimm/dxn130

PubMed ID: 16356863

Title: Structural and mutational analyses of a CD8alphabeta heterodimer and comparison with the CD8alphaalpha homodimer.

PubMed ID: 16356863

DOI: 10.1016/j.immuni.2005.11.002

PubMed ID: 18929574

Title: The crystal structure of CD8 in complex with YTS156.7.7 Fab and interaction with other CD8 antibodies define the binding mode of CD8 alphabeta to MHC class I.

PubMed ID: 18929574

DOI: 10.1016/j.jmb.2008.09.069

Sequence Information:

  • Length: 213
  • Mass: 24288
  • Checksum: 138D2DCA43215BDB
  • Sequence:
  • MQPWLWLVFS MKLAALWSSS ALIQTPSSLL VQTNHTAKMS CEVKSISKLT SIYWLRERQD 
    PKDKYFEFLA SWSSSKGVLY GESVDKKRNI ILESSDSRRP FLSIMNVKPE DSDFYFCATV 
    GSPKMVFGTG TKLTVVDVLP TTAPTKKTTL KMKKKKQCPF PHPETQKGLT CSLTTLSLLV 
    VCILLLLAFL GVAVYFYCVR RRARIHFMKQ FHK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.