Genular: Defining Cellular Identity and Function

Details for: Cdc25a

Gene ID: 12530

Symbol: Cdc25a

Ensembl ID: ENSMUSG00000032477

Description: cell division cycle 25A

Associated with

Activation of atr in response to replication stress
(R-MMU-176187)
Cell cycle, mitotic
(R-MMU-69278)
Cell cycle checkpoints
(R-MMU-69620)
Cyclin a/b1/b2 associated events during g2/m transition
(R-MMU-69273)
Cyclin a:cdk2-associated events at s phase entry
(R-MMU-69656)
Cyclin e associated events during g1/s transition
(R-MMU-69202)
Deubiquitination
(R-MMU-5688426)
G1/s dna damage checkpoints
(R-MMU-69615)
G1/s transition
(R-MMU-69206)
G2/m checkpoints
(R-MMU-69481)
G2/m transition
(R-MMU-69275)
Metabolism of proteins
(R-MMU-392499)
Mitotic g1 phase and g1/s transition
(R-MMU-453279)
Mitotic g2-g2/m phases
(R-MMU-453274)
P53-independent dna damage response
(R-MMU-69610)
P53-independent g1/s dna damage checkpoint
(R-MMU-69613)
Post-translational protein modification
(R-MMU-597592)
S phase
(R-MMU-69242)
Ub-specific processing proteases
(R-MMU-5689880)
Ubiquitin mediated degradation of phosphorylated cdc25a
(R-MMU-69601)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Cellular response to uv
(GO:0034644)
Cytoplasm
(GO:0005737)
G1/s transition of mitotic cell cycle
(GO:0000082)
G2/m transition of mitotic cell cycle
(GO:0000086)
Hydrolase activity
(GO:0016787)
Nucleus
(GO:0005634)
Phosphoprotein phosphatase activity
(GO:0004721)
Positive regulation of cell cycle g2/m phase transition
(GO:1902751)
Positive regulation of cholangiocyte proliferation
(GO:1904056)
Positive regulation of g2/mi transition of meiotic cell cycle
(GO:0110032)
Positive regulation of g2/m transition of mitotic cell cycle
(GO:0010971)
Protein-folding chaperone binding
(GO:0051087)
Protein dephosphorylation
(GO:0006470)
Protein kinase binding
(GO:0019901)
Protein tyrosine phosphatase activity
(GO:0004725)
Response to radiation
(GO:0009314)

Other Information

Proteins

M-phase inducer phosphatase 1

Genular Protein ID: 1967811448

Symbol: MPIP1_MOUSE

Name: M-phase inducer phosphatase 1

UniProtKB Accession Codes:

P48964 E9PVD0

Database IDs:

Citations:

PubMed ID: 7635051

Title: Two CDC25 homologues are differentially expressed during mouse development.

PubMed ID: 7635051

DOI: 10.1242/dev.121.7.2047

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 514
Mass: 57806
Checksum: 7D7AD1CB4C39ACF6
Sequence:

MELGPEPPHR RRLFFACSPT PAPQPTGKML FGASAAGGLS PVTNLTVTMD QLEGLGSDCE 
KMEVRNNSSL QRMGSSESTD SGFCLDSPGP LDSKENLEIS LTRINSLPQK LLGCSPALKR 
SHSDSLDHDT FHLIDQDENK ENEAFEFKKP IRPASRHIYE ESKDPFTHRQ NSAPARMLSS 
NESESGNFSP LFIPQSPVKA TLSDEDDGFI DLLDGENMKN DEETPSCMAS LWTAPLVMRR 
PANLADRCGL FDSPSPCGSS TRAVLKRADR SHEEPPRGTK RRKSVPSPVK AKADVPEPAQ 
LPSQSLSLMS SPKGTIENIL DSDPRDLIGD FSKGYLFNTV SGKHQDLKYI SPEIMASVLN 
GKFAGLIKEF VIIDCRYPYE YEGGHIKGAV NLHMEEEVED FLLKNPIVPT DGKRVIVVFH 
CEFSSERGPR MCRYVRERDR LGNEYPKLHY PELYVLKGGY KEFFLKCQSH CEPPSYRPMH 
HEDFKEDLKK FRTKSRTWAG EKSKREMYSR LKKL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.