Genular: Defining Cellular Identity and Function

Details for: Cdc25c

Gene ID: 12532

Symbol: Cdc25c

Ensembl ID: ENSMUSG00000044201

Description: cell division cycle 25C

Associated with

Activation of atr in response to replication stress
(R-MMU-176187)
Cell cycle, mitotic
(R-MMU-69278)
Cell cycle checkpoints
(R-MMU-69620)
Chk1/chk2(cds1) mediated inactivation of cyclin b:cdk1 complex
(R-MMU-75035)
Cyclin a/b1/b2 associated events during g2/m transition
(R-MMU-69273)
G2/m checkpoints
(R-MMU-69481)
G2/m dna damage checkpoint
(R-MMU-69473)
G2/m transition
(R-MMU-69275)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Mitotic g2-g2/m phases
(R-MMU-453274)
Polo-like kinase mediated events
(R-MMU-156711)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate pkns
(R-MMU-5625740)
Rna polymerase ii transcription
(R-MMU-73857)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
(R-MMU-6804115)
Tp53 regulates transcription of cell cycle genes
(R-MMU-6791312)
Transcriptional regulation by tp53
(R-MMU-3700989)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Cytoplasm
(GO:0005737)
G2/m transition of mitotic cell cycle
(GO:0000086)
Hydrolase activity
(GO:0016787)
Mitochondrial intermembrane space
(GO:0005758)
Nucleus
(GO:0005634)
Perinuclear region of cytoplasm
(GO:0048471)
Phosphoprotein phosphatase activity
(GO:0004721)
Positive regulation of cell cycle g2/m phase transition
(GO:1902751)
Positive regulation of g2/mi transition of meiotic cell cycle
(GO:0110032)
Positive regulation of g2/m transition of mitotic cell cycle
(GO:0010971)
Protein binding
(GO:0005515)
Protein dephosphorylation
(GO:0006470)
Protein kinase binding
(GO:0019901)
Protein tyrosine phosphatase activity
(GO:0004725)
Ww domain binding
(GO:0050699)

Other Information

Proteins

M-phase inducer phosphatase 3

Genular Protein ID: 3555890383

Symbol: MPIP3_MOUSE

Name: M-phase inducer phosphatase 3

UniProtKB Accession Codes:

P48967 Q99KG6

Database IDs:

Citations:

PubMed ID: 7601309

Title: The distinct and developmentally regulated patterns of expression of members of the mouse Cdc25 gene family suggest differential functions during gametogenesis.

PubMed ID: 7601309

DOI: 10.1006/dbio.1995.1207

PubMed ID: 8276463

Title: Cloning and characterization of a cdc25 phosphatase from mouse lymphocytes.

PubMed ID: 8276463

DOI: 10.1007/bf00188612

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 447
Mass: 50046
Checksum: 513E51BAB3D1A39E
Sequence:

MSTGPIPPAS EEGSFVSAPS FRSKQRKILH LLLERNTSFT IRSDFPESPK DKLHDSANLS 
ILSGGTPKCC LDLSNLSSGE MSASPLTTSA DLEDNGSLDS SGPLDRQLTG KDFHQDLMKG 
IPVQLLCSTP NAMNHGHRKK IAKRSTSAHK ENINTSLKAL EWEAPRTPRF RKMPGGPLTS 
PLCELEMKHL GSPITTVPKL SQNVKLEDQE RISEDPMECS LGDQDAKGLS LRKMVPLCDM 
NAIQMEEEES GSELLIGDFS KVCVLPTVPG KHPDLKYISP DTVAALLSGK FQSVIERFYI 
IDCRYPYEYL GGHILGALNL HSQKELHEFF LRKPVVPLDI QKRVIIVFLC EFSSERGPRM 
CRSLREKDRA LNQYPALYYP ELYILKGGYR DFFPEYMELC DPQSYCPMLH QDHQAELLSW 
RSQSKAQEGE RQLQGQIALL VKGASPQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.