Details for: Cdc42

Gene ID: 12540

Symbol: Cdc42

Ensembl ID: ENSMUSG00000006699

Description: cell division cycle 42

Associated with

Other Information

Genular Protein ID: 91803426

Symbol: CDC42_MOUSE

Name: G25K GTP-binding protein

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8464478

Title: Oncogene ect2 is related to regulators of small GTP-binding proteins.

PubMed ID: 8464478

DOI: 10.1038/362462a0

PubMed ID: 9224952

Title: Complete cDNAs for CDC42 from chicken cochlea and mouse liver.

PubMed ID: 9224952

DOI: 10.1016/s0167-4781(97)00027-4

PubMed ID: 8954774

Title: Genomic organization and chromosomal location of murine Cdc42.

PubMed ID: 8954774

DOI: 10.1006/geno.1996.0586

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10490598

Title: The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins.

PubMed ID: 10490598

DOI: 10.1128/mcb.19.10.6585

PubMed ID: 10934474

Title: The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42.

PubMed ID: 10934474

DOI: 10.1038/35019573

PubMed ID: 9535835

Title: Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7.

PubMed ID: 9535835

DOI: 10.1074/jbc.273.15.8616

PubMed ID: 12773384

Title: TCGAP, a multidomain Rho GTPase-activating protein involved in insulin-stimulated glucose transport.

PubMed ID: 12773384

DOI: 10.1093/emboj/cdg262

PubMed ID: 15710388

Title: Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.

PubMed ID: 15710388

DOI: 10.1016/j.febslet.2005.01.006

PubMed ID: 16968698

Title: Identification of a DOCK180-related guanine nucleotide exchange factor that is capable of mediating a positive feedback activation of Cdc42.

PubMed ID: 16968698

DOI: 10.1074/jbc.m606248200

PubMed ID: 17000758

Title: Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor Dbs.

PubMed ID: 17000758

DOI: 10.1128/mcb.00670-06

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22461490

Title: DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses.

PubMed ID: 22461490

DOI: 10.1182/blood-2012-01-407098

PubMed ID: 22494997

Title: Age-related guanine nucleotide exchange factor, mouse Zizimin2, induces filopodia in bone marrow-derived dendritic cells.

PubMed ID: 22494997

DOI: 10.1186/1742-4933-9-2

PubMed ID: 24352656

Title: Rho-GTPase-activating protein interacting with Cdc-42-interacting protein 4 homolog 2 (Rich2): a new Ras-related C3 botulinum toxin substrate 1 (Rac1) GTPase-activating protein that controls dendritic spine morphogenesis.

PubMed ID: 24352656

DOI: 10.1074/jbc.m113.534636

PubMed ID: 25851601

Title: The RhoGEF DOCK10 is essential for dendritic spine morphogenesis.

PubMed ID: 25851601

DOI: 10.1091/mbc.e14-08-1310

PubMed ID: 26969129

Title: Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2.

PubMed ID: 26969129

DOI: 10.1186/s13041-016-0206-6

Sequence Information:

  • Length: 191
  • Mass: 21259
  • Checksum: 51A437E22A4D8FFF
  • Sequence:
  • MQTIKCVVVG DGAVGKTCLL ISYTTNKFPS EYVPTVFDNY AVTVMIGGEP YTLGLFDTAG 
    QEDYDRLRPL SYPQTDVFLV CFSVVSPSSF ENVKEKWVPE ITHHCPKTPF LLVGTQIDLR 
    DDPSTIEKLA KNKQKPITPE TAEKLARDLK AVKYVECSAL TQKGLKNVFD EAILAALEPP 
    EPKKSRRCVL L

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.