Details for: Cdh2

Gene ID: 12558

Symbol: Cdh2

Ensembl ID: ENSMUSG00000024304

Description: cadherin 2

Associated with

Other Information

Genular Protein ID: 2515740693

Symbol: CADH2_MOUSE

Name: Cadherin-2

UniProtKB Accession Codes:

P15116 Q64260 Q6GU11

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEBI 15 ChiTaRS 1 DIP 1 DNASU 1 EMBL 5 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 79 Gene3D 2 GeneTree 1 Genevisible 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MGI 1 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 24 PDBsum 10 PIR 1 PRINTS 2 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 4 RefSeq 1 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 3 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 2762814

Title: Neural cadherin: role in selective cell-cell adhesion.

PubMed ID: 2762814

DOI: 10.1126/science.2762814

PubMed ID: 1528849

Title: Genomic structure and chromosomal mapping of the mouse N-cadherin gene.

PubMed ID: 1528849

DOI: 10.1073/pnas.89.18.8443

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8879495

Title: A comprehensive survey of the cadherins expressed in the testes of fetal, immature, and adult mice utilizing the polymerase chain reaction.

PubMed ID: 8879495

DOI: 10.1095/biolreprod55.4.822

PubMed ID: 11433297

Title: N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling.

PubMed ID: 11433297

DOI: 10.1038/35083041

PubMed ID: 15479741

Title: Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation.

PubMed ID: 15479741

DOI: 10.1083/jcb.200402096

PubMed ID: 17988630

Title: Activity-induced protocadherin arcadlin regulates dendritic spine number by triggering N-cadherin endocytosis via TAO2beta and p38 MAP kinases.

PubMed ID: 17988630

DOI: 10.1016/j.neuron.2007.08.020

PubMed ID: 19805319

Title: Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation.

PubMed ID: 19805319

DOI: 10.1073/pnas.0908507106

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21366346

Title: Sequential binding of calcium leads to dimerization in neural cadherin.

PubMed ID: 21366346

DOI: 10.1021/bi101872b

PubMed ID: 23392350

Title: The kinase domains of obscurin interact with intercellular adhesion proteins.

PubMed ID: 23392350

DOI: 10.1096/fj.12-221317

PubMed ID: 23001562

Title: Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene.

PubMed ID: 23001562

DOI: 10.1093/hmg/dds398

PubMed ID: 25232112

Title: Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization.

PubMed ID: 25232112

DOI: 10.1523/jneurosci.1280-14.2014

PubMed ID: 24952463

Title: MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin.

PubMed ID: 24952463

DOI: 10.1038/ncb2993

PubMed ID: 26403541

Title: Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function.

PubMed ID: 26403541

DOI: 10.1038/ncomms9391

PubMed ID: 26750727

Title: Knock-down of ZBED6 in insulin-producing cells promotes N-cadherin junctions between beta-cells and neural crest stem cells in vitro.

PubMed ID: 26750727

DOI: 10.1038/srep19006

PubMed ID: 7885471

Title: Structural basis of cell-cell adhesion by cadherins.

PubMed ID: 7885471

DOI: 10.1038/374327a0

PubMed ID: 31650526

Title: Novel variants in CDH2 are associated with a new syndrome including Peters anomaly.

PubMed ID: 31650526

DOI: 10.1111/cge.13660

PubMed ID: 34702855

Title: CDH2 mutation affecting N-cadherin function causes attention-deficit hyperactivity disorder in humans and mice.

PubMed ID: 34702855

DOI: 10.1038/s41467-021-26426-1

PubMed ID: 9655503

Title: Structure-function analysis of cell adhesion by neural (N-) cadherin.

PubMed ID: 9655503

DOI: 10.1016/s0896-6273(00)80496-1

PubMed ID: 21300292

Title: The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins.

PubMed ID: 21300292

DOI: 10.1016/j.str.2010.11.016

PubMed ID: 25253890

Title: Structural and energetic determinants of adhesive binding specificity in type I cadherins.

PubMed ID: 25253890

DOI: 10.1073/pnas.1416737111

Sequence Information:

  • Length: 906
  • Mass: 99796
  • Checksum: BDAB8063A23E1F13
  • Sequence:
    • MCRIAGAPRT LLPLLAALLQ ASVEASGEIA LCKTGFPEDV YSAVLPKDVH EGQPLLNVKF 
SNCNRKRKVQ YESSEPADFK VDEDGTVYAV RSFPLTAEQA KFLIYAQDKE TQEKWQVAVN 
LSREPTLTEE PMKEPHEIEE IVFPRQLAKH SGALQRQKRD WVIPPINLPE NSRGPFPQEL 
VRIRSDRDKN LSLRYSVTGP GADQPPTGIF IINPISGQLS VTKPLDRELI ARFHLRAHAV 
DINGNQVENP IDIVINVIDM NDNRPEFLHQ VWNGSVPEGS KPGTYVMTVT AIDADDPNAL 
NGMLRYRILS QAPSTPSPNM FTINNETGDI ITVAAGLDRE KVQQYTLIIQ ATDMEGNPTY 
GLSNTATAVI TVTDVNDNPP EFTAMTFYGE VPENRVDVIV ANLTVTDKDQ PHTPAWNAAY 
RISGGDPTGR FAILTDPNSN DGLVTVVKPI DFETNRMFVL TVAAENQVPL AKGIQHPPQS 
TATVSVTVID VNENPYFAPN PKIIRQEEGL HAGTMLTTLT AQDPDRYMQQ NIRYTKLSDP 
ANWLKIDPVN GQITTIAVLD RESPNVKNNI YNATFLASDN GIPPMSGTGT LQIYLLDIND 
NAPQVLPQEA ETCETPEPNS INITALDYDI DPNAGPFAFD LPLSPVTIKR NWTINRLNGD 
FAQLNLKIKF LEAGIYEVPI IITDSGNPPK SNISILRVKV CQCDSNGDCT DVDRIVGAGL 
GTGAIIAILL CIIILLILVL MFVVWMKRRD KERQAKQLLI DPEDDVRDNI LKYDEEGGGE 
EDQDYDLSQL QQPDTVEPDA IKPVGIRRLD ERPIHAEPQY PVRSAAPHPG DIGDFINEGL 
KAADNDPTAP PYDSLLVFDY EGSGSTAGSL SSLNSSSSGG DQDYDYLNDW GPRFKKLADM 
YGGGDD

Genular Protein ID: 1448752809

Symbol: Q8BSI9_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8BSI9

Database IDs:

AGR 1 ARBA 14 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 Genevisible 1 InterPro 7 KEGG 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 RefSeq 1 RuleBase 2 SAM 3 SMART 2 SUPFAM 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 906
  • Mass: 99856
  • Checksum: 44B04B7DB5AFD0B2
  • Sequence:
    • MCRIAGAPRT LLPLLAALLQ ASVETSGEIA LCKTGFPEDV YSAVLPKDVH EGQPLLNVKF 
SNCNRKRKVQ YESSEPADFK VDEDGTVYAV RSFPLTAEQA KFLIYAQDKE TQEKWQVAVN 
LSREPTLTEE PMKEPHEIEE IVFPRQLAKH SGALQRQKRD WVIPPINLPE NSRGPFPQEL 
VRIRSDRDKN LSLRYSVTGP GADQPPTGIF IINPISGQLS VTKPLDRELI ARFHLRAHAV 
DINGNQVENP IDIVINVIDM NDNRPEFLHQ VWNGSVPEGS KPGTYVMTVT AIDADDPNAL 
NGMLRYRILS QAPSTPSPNM FTINNETGDI ITVATGLDRE KVQQYTLIIQ ATDMEGNPTY 
GLSNTATAVI TVTDVNDNPP EFTAMTFYGE VPENRVDVIV ANLTVTDKDQ PHTPAWNAAY 
RISGGDPTGR FAILTDPNSN DGLVTVVKPI DFETNRMFVL TVAAENQVPL AKGIQHPPQS 
TATVSVTVID VNENPYFAPN PKIIRQEEGL HAGTMLTTLT AQDPDRYMQQ NIRYTKLSDP 
ANWLKIDPVN GQITTIAVLD RESPNVKNNI YNATFLASDN GIPPMSGTGT LQIYLLDIND 
NAPQVLPQEA ETCETPEPNS INITALDYDI DPNAGPFAFD LPLSPVTIKR NWTINRLNGD 
FAQLNLKIKF LEAGIYEVPI IITDSGNPPK SNISILRVKV CQCDSNGDCT DVDRIVGAGL 
GTGAIIAILL CIIILLILVL MFVVWMKRRD KERQAKQLLI DPEDDVRDNI LKYDEEGGGE 
EDQDYDLSQL QQPDTVEPDA IKPVGIRRLD ERPIHAEPQY PVRSAAPHPG DIGDFINEGL 
KAADNDPTAP PYDSLLVFDY EGSGSTAGSL SSLNSSSSGG DQDYDYLNDW GPRFKKLADM 
YGGGDD

Genular Protein ID: 3559585346

Symbol: Q3UIC2_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UIC2

Database IDs:

AGR 1 ARBA 14 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 Genevisible 1 InterPro 7 KEGG 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 RefSeq 1 RuleBase 2 SAM 3 SMART 2 SUPFAM 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 906
  • Mass: 99808
  • Checksum: A52D780CDBFC3434
  • Sequence:
    • MCRIAGAPRT LLPLLAALLQ ASVEASGEIA LCKTGFPEDV YSAVLPKDVH EGQPLLNVKF 
SNCNRKRKVQ YESSEPADFK VDEDGTVYAV RSFPLTAEQA KFLIYAQDKE TQEKWQVAVN 
LSREPTLTEE PMKEPHEIEE IVFPRQLAKH SGALQRQKRD WVIPPINLPE NSRGPFPQEL 
VRIRSDRDKN LSLRYSVTGP GADQPPTGIF IINPISGQLS VTKPLDRELI ARFHLRAHAV 
DINGNQVENP IDIVINVIDM NDNRPEFLHQ VWNGSVPEGS KPGTYVMTVT AIDADDPNAL 
NGMLRYRILS QAPSTPSPNM FTINNETGDI ITVAAGLDRE KVQQYTLIIQ ATDMEGNPTY 
GLSNTATAVI TVTDVNDNPP EFTAMTFYGE VPENRVDVIV ANLTVTDKDQ PHTPAWNAAY 
RISGGDPTGR FAILTDPNSN DGLVTVVKPI DFETNRMFVL TVAAENQVPL AKGIQHPPQS 
TATVSVTVID VNENPYFAPN PKIIRQEEGL HAGTMLTTLT AQDPDRYMQQ NIRYTKLSDP 
ANWLKIDPVN GQITTIAVLD RESPNVKNNI YNATFLASDN GIPPMSGTGT LQIYLLDIND 
NAPQVLPQEA ETCETPEPNS INITALDYDI DPNAGPFAFD LSLCSVTIKR NWTINRLNGD 
FAQLNLKIKF LEAGIYEVPI IITDSGNPPK SNISILRVKV CQCDSNGDCT DVDRIVGAGL 
GTGAIIAILL CIIILLILVL MFVVWMKRRD KERQAKQLLI DPEDDVRDNI LKYDEEGGGE 
EDQDYDLSQL QQPDTVEPDA IKPVGIRRLD ERPIHAEPQY PVRSAAPHPG DIGDFINEGL 
KSADNDPTAP PYDSLLVFDY EGSGSTAGSL SSLNSSSSGG DQDYDYLNDW GPRFKKLADM 
YGGGDD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.