Genular: Defining Cellular Identity and Function

Details for: Cdk7

Gene ID: 12572

Symbol: Cdk7

Ensembl ID: ENSMUSG00000069089

Description: cyclin dependent kinase 7

Associated with

Cell cycle, mitotic
(R-MMU-69278)
Cyclin a/b1/b2 associated events during g2/m transition
(R-MMU-69273)
Cyclin a:cdk2-associated events at s phase entry
(R-MMU-69656)
Cyclin d associated events in g1
(R-MMU-69231)
Cyclin e associated events during g1/s transition
(R-MMU-69202)
Dual incision in tc-ner
(R-MMU-6782135)
Formation of incision complex in gg-ner
(R-MMU-5696395)
Formation of rna pol ii elongation complex
(R-MMU-112382)
Formation of tc-ner pre-incision complex
(R-MMU-6781823)
Formation of the early elongation complex
(R-MMU-113418)
G1 phase
(R-MMU-69236)
G1/s transition
(R-MMU-69206)
G2/m transition
(R-MMU-69275)
Gap-filling dna repair synthesis and ligation in tc-ner
(R-MMU-6782210)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Global genome nucleotide excision repair (gg-ner)
(R-MMU-5696399)
Metabolism of rna
(R-MMU-8953854)
Mitotic g1 phase and g1/s transition
(R-MMU-453279)
Mitotic g2-g2/m phases
(R-MMU-453274)
Mrna capping
(R-MMU-72086)
Nucleotide excision repair
(R-MMU-5696398)
Rna pol ii ctd phosphorylation and interaction with ce
(R-MMU-77075)
Rna polymerase ii pre-transcription events
(R-MMU-674695)
Rna polymerase ii promoter escape
(R-MMU-73776)
Rna polymerase ii transcribes snrna genes
(R-MMU-6807505)
Rna polymerase ii transcription
(R-MMU-73857)
Rna polymerase ii transcription elongation
(R-MMU-75955)
Rna polymerase ii transcription initiation
(R-MMU-75953)
Rna polymerase ii transcription initiation and promoter clearance
(R-MMU-76042)
Rna polymerase ii transcription pre-initiation and promoter opening
(R-MMU-73779)
Rna polymerase i promoter clearance
(R-MMU-73854)
Rna polymerase i promoter escape
(R-MMU-73772)
Rna polymerase i transcription
(R-MMU-73864)
Rna polymerase i transcription initiation
(R-MMU-73762)
Rna polymerase i transcription termination
(R-MMU-73863)
Runx1 regulates transcription of genes involved in differentiation of hscs
(R-MMU-8939236)
S phase
(R-MMU-69242)
Tp53 regulates transcription of dna repair genes
(R-MMU-6796648)
Transcription-coupled nucleotide excision repair (tc-ner)
(R-MMU-6781827)
Transcriptional regulation by runx1
(R-MMU-8878171)
Transcriptional regulation by tp53
(R-MMU-3700989)
Atp-dependent activity, acting on dna
(GO:0008094)
Atp binding
(GO:0005524)
Cak-ercc2 complex
(GO:0070516)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Cyclin-dependent protein kinase activating kinase holoenzyme complex
(GO:0019907)
Cyclin-dependent protein serine/threonine kinase activity
(GO:0004693)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dna damage response
(GO:0006974)
Dna repair
(GO:0006281)
Fibrillar center
(GO:0001650)
Kinase activity
(GO:0016301)
Male germ cell nucleus
(GO:0001673)
Nucleoplasm
(GO:0005654)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Phosphorylation
(GO:0016310)
Plasma membrane
(GO:0005886)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein kinase activity
(GO:0004672)
Protein phosphorylation
(GO:0006468)
Protein serine/threonine kinase activity
(GO:0004674)
Protein stabilization
(GO:0050821)
Regulation of cell cycle
(GO:0051726)
Regulation of g1/s transition of mitotic cell cycle
(GO:2000045)
Rna polymerase ii ctd heptapeptide repeat kinase activity
(GO:0008353)
Transcription by rna polymerase ii
(GO:0006366)
Transcription factor tfiih core complex
(GO:0000439)
Transcription factor tfiih holo complex
(GO:0005675)
Transcription factor tfiik complex
(GO:0070985)
Transcription initiation at rna polymerase ii promoter
(GO:0006367)
Transferase activity
(GO:0016740)

Other Information

Proteins

Cyclin-dependent kinase 7

Genular Protein ID: 2321468924

Symbol: CDK7_MOUSE

Name: Cyclin-dependent kinase 7

UniProtKB Accession Codes:

Q03147 Q99KK3

Database IDs:

Citations:

PubMed ID: 7935441

Title: Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase.

PubMed ID: 7935441

DOI: 10.1128/mcb.14.11.7265-7275.1994

PubMed ID: 7959010

Title: Sequence of the cDNA encoding murine CRK4 protein kinase.

PubMed ID: 7959010

DOI: 10.1016/0378-1119(94)90169-4

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1281307

Title: An Eph-related receptor protein tyrosine kinase gene segmentally expressed in the developing mouse hindbrain.

PubMed ID: 1281307

PubMed ID: 8444355

Title: Novel CDC2-related protein kinases produced in murine hematopoietic stem cells.

PubMed ID: 8444355

DOI: 10.1016/0378-1119(93)90411-u

PubMed ID: 1459009

Title: Identification of new protein kinase genes, similar to kinases of the cdc2 family and expressed in murine hematopoietic stem cells.

PubMed ID: 1459009

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 346
Mass: 38968
Checksum: 455FFAB2CFEDEB3E
Sequence:

MAVDVKSRAK RYEKLDFLGE GQFATVYKAR DKNTNQIVAI KKIKLGHRSE AKDGINRTAL 
REIKLLQELS HPNIIGLLDA FGHKSNISLV FDFMETDLEV IIKDNSLVLT PSHIKAYMLM 
TLQGLEYLHQ HWILHRDLKP NNLLLDENGV LKLADFGLAK SFGSPNRAYT HQVVTRWYRA 
PELLFGARMY GVGVDMWAVG CILAELLLRV PFLPGDSDLD QLTRIFETLG TPTEEQWPDM 
CSLPDYVTFK SFPGVPLQHI FIAAGDDLLE LIQGLFLFNP CTRTTASQAL KTKYFSNRPG 
PTPGCQLPRP NCPVEALKEP ANPTVATKRK RAEALEQGIL PKKLIF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cdk7

Associated with

Other Information

Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase. PubMed ID: 7935441

Sequence of the cDNA encoding murine CRK4 protein kinase. PubMed ID: 7959010

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

An Eph-related receptor protein tyrosine kinase gene segmentally expressed in the developing mouse hindbrain. PubMed ID: 1281307

Novel CDC2-related protein kinases produced in murine hematopoietic stem cells. PubMed ID: 8444355

Identification of new protein kinase genes, similar to kinases of the cdc2 family and expressed in murine hematopoietic stem cells. PubMed ID: 1459009

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079