Genular: Defining Cellular Identity and Function

Details for: Cdkn1c

Gene ID: 12577

Symbol: Cdkn1c

Ensembl ID: ENSMUSG00000037664

Description: cyclin dependent kinase inhibitor 1C

Associated with

Cell cycle, mitotic
(R-MMU-69278)
Cyclin d associated events in g1
(R-MMU-69231)
G1 phase
(R-MMU-69236)
Mitotic g1 phase and g1/s transition
(R-MMU-453279)
Adrenal gland development
(GO:0030325)
Camera-type eye development
(GO:0043010)
Cell cycle
(GO:0007049)
Cyclin-dependent protein serine/threonine kinase inhibitor activity
(GO:0004861)
Cytoplasm
(GO:0005737)
Digestive system development
(GO:0055123)
Embryonic placenta morphogenesis
(GO:0060669)
Genomic imprinting
(GO:0071514)
Kidney development
(GO:0001822)
Molecular function inhibitor activity
(GO:0140678)
Multicellular organism growth
(GO:0035264)
Myeloid cell differentiation
(GO:0030099)
Negative regulation of cyclin-dependent protein kinase activity
(GO:1904030)
Negative regulation of cyclin-dependent protein serine/threonine kinase activity
(GO:0045736)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of epithelial cell proliferation
(GO:0050680)
Negative regulation of kinase activity
(GO:0033673)
Negative regulation of mitotic cell cycle
(GO:0045930)
Negative regulation of phosphorylation
(GO:0042326)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neuron maturation
(GO:0042551)
Nucleus
(GO:0005634)
Placenta development
(GO:0001890)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of transforming growth factor beta receptor signaling pathway
(GO:0030511)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein kinase inhibitor activity
(GO:0004860)
Regulation of cell cycle
(GO:0051726)
Regulation of exit from mitosis
(GO:0007096)
Regulation of lens fiber cell differentiation
(GO:1902746)
Skeletal system development
(GO:0001501)
Uterus development
(GO:0060065)

Other Information

Proteins

Cyclin-dependent kinase inhibitor 1C
Q791X1_MOUSE

Genular Protein ID: 3508603729

Symbol: CDN1C_MOUSE

Name: Cyclin-dependent kinase inhibitor 1C

UniProtKB Accession Codes:

P49919 G3UW61

Database IDs:

Citations:

PubMed ID: 7729683

Title: Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution.

PubMed ID: 7729683

DOI: 10.1101/gad.9.6.639

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 7729684

Title: p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene.

PubMed ID: 7729684

DOI: 10.1101/gad.9.6.650

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

Sequence Information:

Length: 348
Mass: 37372
Checksum: 100032B2F76BEC92
Sequence:

MGMSDVYLRS RTAMERLASS DTFPVIARSS ACRSLFGPVD HEELGRELRM RLAELNAEDQ 
NRWDFNFQQD VPLRGPGRLQ WMEVDSESVP AFYRETVQVG RCRLQLGPRP PPVAVAVIPR 
SGPPAGEAPD GLEEAPEQPP SAPASAVVAE PTPPATPAPA SDLTSDPIPE VTLVATSDPT 
PDPIPDANPD VATRDGEEQV PEQVSEQGEE SGAEPGDELG TEPVSEQGEE QGAEPVEEKD 
EEPEEEQGAE PVEEQGAEPV EEQNGEPVEE QDENQEQRGQ ELKDQPLSGI PGRPAPGTAA 
ANANDFFAKR KRTAQENKAS NDVPPGCPSP NVAPGVGAVE QTPRKRLR

Genular Protein ID: 1628610412

Symbol: Q791X1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q791X1

Database IDs:

Citations:

PubMed ID: 10545601

Title: A human p57(KIP2) transgene is not activated by passage through the maternal mouse germline.

PubMed ID: 10545601

DOI: 10.1093/hmg/8.12.2211

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 335
Mass: 35903
Checksum: E5C40675287FEB3F
Sequence:

MERLASSDTF PVIARSSACR SLFGPVDHEE LGRELRMRLA ELNAEDQNRW DFNFQQDVPL 
RGPGRLQWME VDSESVPAFY RETVQVGRCR LQLGPRPPPV AVAVIPRSGP PAGEAPDGLE 
EAPEQPPSAP ASAVVAEPTP PATPAPASDL TSDPIPEVTL VATSDPTPDP IPDANPDVAT 
RDGEEQVPEQ VSEQGEESGA EPGDELGTEP VSEQGEEQGA EPVEEKDEEP EEEQGAEPVE 
EQGAEPVEEQ NGEPVEEQDE NQEQRGQELK DQPLSGIPGR PAPGTAAANA NDFFAKRKRT 
AQENKASNDV PPGCPSPNVA PGVGAVEQTP RKRLR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cdkn1c

Associated with

Other Information

Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. PubMed ID: 7729683

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene. PubMed ID: 7729684

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315

A human p57(KIP2) transgene is not activated by passage through the maternal mouse germline. PubMed ID: 10545601