Genular: Defining Cellular Identity and Function

Details for: Cdkn2d

Gene ID: 12581

Symbol: Cdkn2d

Ensembl ID: ENSMUSG00000096472

Description: cyclin dependent kinase inhibitor 2D

Associated with

Autophagic cell death
(GO:0048102)
Cell cycle
(GO:0007049)
Cyclin-dependent protein serine/threonine kinase inhibitor activity
(GO:0004861)
Cyclin d2-cdk4 complex
(GO:0097129)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dna synthesis involved in dna repair
(GO:0000731)
Negative regulation of cell cycle g1/s phase transition
(GO:1902807)
Negative regulation of cell growth
(GO:0030308)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0043154)
Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage
(GO:1902230)
Negative regulation of phosphorylation
(GO:0042326)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Protein kinase binding
(GO:0019901)
Regulation of cyclin-dependent protein serine/threonine kinase activity
(GO:0000079)
Regulation of g1/s transition of mitotic cell cycle
(GO:2000045)
Response to retinoic acid
(GO:0032526)
Response to uv
(GO:0009411)
Response to vitamin d
(GO:0033280)
Sensory perception of sound
(GO:0007605)

Other Information

Proteins

Cyclin-dependent kinase 4 inhibitor D
Q3US51_MOUSE

Genular Protein ID: 297170733

Symbol: CDN2D_MOUSE

Name: Cyclin-dependent kinase 4 inhibitor D

UniProtKB Accession Codes:

Q60773 Q60794 Q91YV3

Database IDs:

Citations:

PubMed ID: 7739547

Title: Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6.

PubMed ID: 7739547

DOI: 10.1128/mcb.15.5.2672

PubMed ID: 7739548

Title: Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4.

PubMed ID: 7739548

DOI: 10.1128/mcb.15.5.2682

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 9353127

Title: Structure of the cyclin-dependent kinase inhibitor p19Ink4d.

PubMed ID: 9353127

DOI: 10.1038/40202

Sequence Information:

Length: 166
Mass: 17809
Checksum: 7B95D6C2294F9259
Sequence:

MLLEEVCVGD RLSGAAARGD VQEVRRLLHR ELVHPDALNR FGKTALQVMM FGSPAVALEL 
LKQGASPNVQ DASGTSPVHD AARTGFLDTL KVLVEHGADV NALDSTGSLP IHLAIREGHS 
SVVSFLAPES DLHHRDASGL TPLELARQRG AQNLMDILQG HMMIPM

Genular Protein ID: 840722796

Symbol: Q3US51_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3US51

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 145
Mass: 15667
Checksum: 612750B830EE57F2
Sequence:

EEVRRLLHRE LVHPDALNRF GKTALQVMMF GSPAVALELL KQGASPNVQD ASGTSPVHDA 
ARTGFLDTLK VLVEHGADVN ALDSTGSLPI HLAIREGHSS VVSFLAPESD LHHRDASGLT 
PLELARQRGA QNLMDILQGH MMIPM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cdkn2d

Associated with

Other Information

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6. PubMed ID: 7739547

Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4. PubMed ID: 7739548

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Structure of the cyclin-dependent kinase inhibitor p19Ink4d. PubMed ID: 9353127

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073