Genular: Defining Cellular Identity and Function

Details for: Ift81

Gene ID: 12589

Symbol: Ift81

Ensembl ID: ENSMUSG00000029469

Description: intraflagellar transport 81

Associated with

Intraflagellar transport
(R-MMU-5620924)
Organelle biogenesis and maintenance
(R-MMU-1852241)
Cell differentiation
(GO:0030154)
Cell projection
(GO:0042995)
Cell projection organization
(GO:0030030)
Centriole
(GO:0005814)
Centrosome
(GO:0005813)
Ciliary basal body
(GO:0036064)
Cilium
(GO:0005929)
Cilium assembly
(GO:0060271)
Cytoplasm
(GO:0005737)
Intraciliary anterograde transport
(GO:0035720)
Intraciliary transport
(GO:0042073)
Intraciliary transport involved in cilium assembly
(GO:0035735)
Intraciliary transport particle b
(GO:0030992)
Multicellular organism development
(GO:0007275)
Protein binding
(GO:0005515)
Regulation of smoothened signaling pathway
(GO:0008589)
Spermatogenesis
(GO:0007283)
Sperm flagellum assembly
(GO:0120316)
Sperm midpiece
(GO:0097225)
Sperm principal piece
(GO:0097228)
Tubulin binding
(GO:0015631)

Other Information

Proteins

Intraflagellar transport protein 81 homolog

Genular Protein ID: 1210640407

Symbol: IFT81_MOUSE

Name: Intraflagellar transport protein 81 homolog

UniProtKB Accession Codes:

O35594 Q8R4W2 Q9CSA1 Q9EQM1

Database IDs:

Citations:

PubMed ID: 9187371

Title: A novel gene suppressed in the ventricle of carnitine-deficient juvenile visceral steatosis mice.

PubMed ID: 9187371

DOI: 10.1016/s0014-5793(97)00429-8

PubMed ID: 11130971

Title: Genomic organization and mapping of mouse CDV (carnitine deficiency-associated gene expressed in ventricle)-1 and its related CDV-1R gene.

PubMed ID: 11130971

DOI: 10.1007/s003350010207

PubMed ID: 12549821

Title: Identification of human CDV-1R and mouse Cdv-1R, two novel proteins with putative signal peptides, especially highly expressed in testis and increased with the male sex maturation.

PubMed ID: 12549821

DOI: 10.1023/a:1021232518628

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10210276

Title: Catecholamine metabolism inhibitors and receptor blockades only partially suppress cardiac hypertrophy of juvenile visceral steatosis mice with systemic carnitine deficiency.

PubMed ID: 10210276

DOI: 10.1016/s0024-3205(99)00042-9

PubMed ID: 19253336

Title: Characterization of mouse IFT complex B.

PubMed ID: 19253336

DOI: 10.1002/cm.20346

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23055941

Title: RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.

PubMed ID: 23055941

DOI: 10.1371/journal.pgen.1002969

PubMed ID: 23810713

Title: Interaction of mouse TTC30/DYF-1 with multiple intraflagellar transport complex B proteins and KIF17.

PubMed ID: 23810713

DOI: 10.1016/j.yexcr.2013.06.010

PubMed ID: 32233951

Title: The essential role of intraflagellar transport protein IFT81 in male mice spermiogenesis and fertility.

PubMed ID: 32233951

DOI: 10.1152/ajpcell.00450.2019

Sequence Information:

Length: 676
Mass: 79285
Checksum: DB059ACCFFDEBAE8
Sequence:

MSDQIKFIVD SLNKEPFKKN YNLITFDSLG PMQLLQVLND VLAEIDPKQD VDIREEMPEQ 
TAKRMLNLLG ILKYKPPGNA TDMSTFRQGL VIGSKPVIYP VLHWLLQRSN ELKKRAYLAR 
FLIKLEVPSE FLQDETVADT NKQYEELMEA FKTLHKECEQ LKTSGFSTAE IRRDISAMEE 
EKDQLMKRVE RLKKRVETVQ NHQRMLKIAR QLRVEKEREE FLAQQKQEQK NQLFHAVQRL 
QRVQNQLKSM RHAAADAKPE SLMKRLEEEI KFNSYMVTEK FPKELESKKK ELHFLQKVVS 
EPAMGHSDLL ELETKVNEVN TEINQLIEKK MMRNEPIEGK LSLYRQQASI ISRKKEAKAE 
ELQETKEKLA SLEREVLVKT NQTREFDGTE VLKGDEFKRY VSKLRSKSTV FKKKHQIIAE 
FKAEFGLLQR TEELLKQRQE TIQHQLRTIE EKKGISGYSY TQEELERVSA LKSEVDEMKG 
RTLDDMSEMV KKLNSLVSEK KSALAPVIKE LRQLRQKCQE LTQECDEKKA QYDSCAAGLE 
SNRSKLEQEV RGLREECLQE ESKYHYTNCM IKNLEVELRR ATDEMKAYVS SDQQEKRKAI 
REQYTKNITE QENLGKKLRE KQKAVRESHG PNMKQAKMWR DLEQLMECKK QCFLKQQSPA 
SIGQVIQEGG EDRLVL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ift81

Associated with

Other Information

A novel gene suppressed in the ventricle of carnitine-deficient juvenile visceral steatosis mice. PubMed ID: 9187371

Genomic organization and mapping of mouse CDV (carnitine deficiency-associated gene expressed in ventricle)-1 and its related CDV-1R gene. PubMed ID: 11130971

Identification of human CDV-1R and mouse Cdv-1R, two novel proteins with putative signal peptides, especially highly expressed in testis and increased with the male sex maturation. PubMed ID: 12549821

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Catecholamine metabolism inhibitors and receptor blockades only partially suppress cardiac hypertrophy of juvenile visceral steatosis mice with systemic carnitine deficiency. PubMed ID: 10210276

Characterization of mouse IFT complex B. PubMed ID: 19253336

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. PubMed ID: 23055941

Interaction of mouse TTC30/DYF-1 with multiple intraflagellar transport complex B proteins and KIF17. PubMed ID: 23810713

The essential role of intraflagellar transport protein IFT81 in male mice spermiogenesis and fertility. PubMed ID: 32233951