Genular: Defining Cellular Identity and Function

Details for: Cel

Gene ID: 12613

Symbol: Cel

Ensembl ID: ENSMUSG00000026818

Description: carboxyl ester lipase

Associated with

Digestion
(R-MMU-8935690)
Digestion and absorption
(R-MMU-8963743)
Digestion of dietary lipid
(R-MMU-192456)
Acetylesterase activity
(GO:0008126)
Carboxylic ester hydrolase activity
(GO:0052689)
Ceramide catabolic process
(GO:0046514)
Cytoplasm
(GO:0005737)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Glycosphingolipid binding
(GO:0043208)
Hydrolase activity
(GO:0016787)
Intestinal cholesterol absorption
(GO:0030299)
Lipid catabolic process
(GO:0016042)
Lipid metabolic process
(GO:0006629)
Lysophospholipase activity
(GO:0004622)
Pancreatic juice secretion
(GO:0030157)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Retinyl-palmitate esterase activity
(GO:0050253)
Sterol esterase activity
(GO:0004771)
Triglyceride lipase activity
(GO:0004806)
Zymogen granule
(GO:0042588)

Other Information

Proteins

Bile salt-activated lipase

Genular Protein ID: 3050281292

Symbol: CEL_MOUSE

Name: Bile salt-activated lipase

UniProtKB Accession Codes:

Q64285

Database IDs:

Citations:

PubMed ID: 8522186

Title: Characterization of the mouse pancreatic/mammary gland cholesterol esterase-encoding cDNA and gene.

PubMed ID: 8522186

DOI: 10.1016/0378-1119(95)00564-m

PubMed ID: 8530060

Title: Molecular cloning and characterization of the mouse carboxyl ester lipase gene and evidence for expression in the lactating mammary gland.

PubMed ID: 8530060

DOI: 10.1006/geno.1995.1221

PubMed ID: 11834744

Title: Charcot-Leyden crystal protein (galectin-10) is not a dual function galectin with lysophospholipase activity but binds a lysophospholipase inhibitor in a novel structural fashion.

PubMed ID: 11834744

DOI: 10.1074/jbc.m200221200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 27509211

Title: Branched fatty acid esters of hydroxy fatty acids are preferred substrates of the MODY8 protein carboxyl ester lipase.

PubMed ID: 27509211

DOI: 10.1021/acs.biochem.6b00565

Sequence Information:

Length: 599
Mass: 65813
Checksum: 9E4428FDFCA8602E
Sequence:

MGRLEVLFLG LTCCLAAACA AKLGAVYTEG GFVEGVNKKL SLLGGDSVDI FKGIPFATAK 
TLENPQRHPG WQGTLKATNF KKRCLQATIT QDNTYGQEDC LYLNIWVPQG RKQVSHNLPV 
MVWIYGGAFL MGSGQGANFL KNYLYDGEEI ATRGNVIVVT FNYRVGPLGF LSTGDANLPG 
NFGLRDQHMA IAWVKRNIAA FGGDPDNITI FGESAGAASV SLQTLSPYNK GLIRRAISQS 
GMALSPWAIQ KNPLFWAKTI AKKVGCPTED TGKMAACLKI TDPRALTLAY KLPVKKQEYP 
VVHYLAFIPV IDGDFIPDDP INLYNNTADI DYIAGINNMD GHLFATIDVP AVDKTKQTVT 
EEDFYRLVSG HTVAKGLKGA QATFDIYTES WAQDPSQENM KKTVVAFETD VLFLIPTEIA 
LAQHKAHAKS AKTYSYLFSH PSRMPIYPKW MGADHADDLQ YVFGKPFATP LGYRPQDRAV 
SKAMIAYWTN FARSGDPNMG NSPVPTHWYP YTLENGNYLD ITKTITSASM KEHLREKFLK 
FWAVTFEVLP TVTGDQDTLT PPEDDSEVAP DPPSDDSQVV PVPPTDDSVE AQMPATIGF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cel

Associated with

Other Information

Characterization of the mouse pancreatic/mammary gland cholesterol esterase-encoding cDNA and gene. PubMed ID: 8522186

Molecular cloning and characterization of the mouse carboxyl ester lipase gene and evidence for expression in the lactating mammary gland. PubMed ID: 8530060

Charcot-Leyden crystal protein (galectin-10) is not a dual function galectin with lysophospholipase activity but binds a lysophospholipase inhibitor in a novel structural fashion. PubMed ID: 11834744