Genular: Defining Cellular Identity and Function

Details for: Cenpa

Gene ID: 12615

Symbol: Cenpa

Ensembl ID: ENSMUSG00000029177

Description: centromere protein A

Associated with

Amplification of signal from the kinetochores
(R-MMU-141424)
Amplification of signal from unattached kinetochores via a mad2 inhibitory signal
(R-MMU-141444)
Cell cycle
(R-MMU-1640170)
Cell cycle, mitotic
(R-MMU-69278)
Cell cycle checkpoints
(R-MMU-69620)
Chromosome maintenance
(R-MMU-73886)
Deposition of new cenpa-containing nucleosomes at the centromere
(R-MMU-606279)
Eml4 and nudc in mitotic spindle formation
(R-MMU-9648025)
Mitotic anaphase
(R-MMU-68882)
Mitotic metaphase and anaphase
(R-MMU-2555396)
Mitotic prometaphase
(R-MMU-68877)
Mitotic spindle checkpoint
(R-MMU-69618)
M phase
(R-MMU-68886)
Nucleosome assembly
(R-MMU-774815)
Resolution of sister chromatid cohesion
(R-MMU-2500257)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate formins
(R-MMU-5663220)
Separation of sister chromatids
(R-MMU-2467813)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Cenp-a containing chromatin
(GO:0061638)
Cenp-a containing chromatin assembly
(GO:0034080)
Cenp-a containing nucleosome
(GO:0043505)
Chromosome
(GO:0005694)
Chromosome, centromeric region
(GO:0000775)
Condensed chromosome, centromeric region
(GO:0000779)
Dna binding
(GO:0003677)
Establishment of mitotic spindle orientation
(GO:0000132)
Kinetochore assembly
(GO:0051382)
Mitotic cytokinesis
(GO:0000281)
Nucleoplasm
(GO:0005654)
Nucleosome
(GO:0000786)
Nucleus
(GO:0005634)
Pericentric heterochromatin
(GO:0005721)
Protein heterodimerization activity
(GO:0046982)
Protein localization to cenp-a containing chromatin
(GO:0061644)
Protein localization to chromosome, centromeric region
(GO:0071459)
Structural constituent of chromatin
(GO:0030527)

Other Information

Proteins

Histone H3-like centromeric protein A

Genular Protein ID: 3532893575

Symbol: CENPA_MOUSE

Name: Histone H3-like centromeric protein A

UniProtKB Accession Codes:

O35216 Q545C9

Database IDs:

Citations:

PubMed ID: 9465302

Title: Gene structure and sequence analysis of mouse centromere proteins A and C.

PubMed ID: 9465302

DOI: 10.1006/geno.1997.5109

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12011073

Title: Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated.

PubMed ID: 12011073

DOI: 10.1074/jbc.m200620200

PubMed ID: 27499292

Title: The flexible ends of CENP-A nucleosome are required for mitotic fidelity.

PubMed ID: 27499292

DOI: 10.1016/j.molcel.2016.06.023

Sequence Information:

Length: 134
Mass: 15509
Checksum: 0381FA6492E43C3D
Sequence:

MGPRRKPQTP RRRPSSPAPG PSRQSSSVGS QTLRRRQKFM WLKEIKTLQK STDLLFRKKP 
FSMVVREICE KFSRGVDFWW QAQALLALQE AAEAFLIHLF EDAYLLSLHA GRVTLFPKDI 
QLTRRIRGFE GGLP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cenpa

Associated with

Other Information

Gene structure and sequence analysis of mouse centromere proteins A and C. PubMed ID: 9465302

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334