Genular: Defining Cellular Identity and Function

Details for: Cer1

Gene ID: 12622

Symbol: Cer1

Ensembl ID: ENSMUSG00000038192

Description: cerberus 1, DAN family BMP antagonist

Associated with

Signaling by bmp
(R-MMU-201451)
Signaling by tgfb family members
(R-MMU-9006936)
Signal transduction
(R-MMU-162582)
Anterior/posterior axis specification
(GO:0009948)
Anterior/posterior pattern specification
(GO:0009952)
Bmp binding
(GO:0036122)
Bone mineralization
(GO:0030282)
Cell migration involved in gastrulation
(GO:0042074)
Cell population proliferation
(GO:0008283)
Cellular response to cadmium ion
(GO:0071276)
Cytokine activity
(GO:0005125)
Determination of dorsal identity
(GO:0048263)
Determination of heart left/right asymmetry
(GO:0061371)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Gastrulation
(GO:0007369)
Growth plate cartilage chondrocyte proliferation
(GO:0003419)
Morphogen activity
(GO:0016015)
Negative regulation of activin receptor signaling pathway
(GO:0032926)
Negative regulation of bmp signaling pathway
(GO:0030514)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of mesoderm development
(GO:2000381)
Negative regulation of wnt signaling pathway
(GO:0030178)
Nervous system development
(GO:0007399)
Protein homodimerization activity
(GO:0042803)
Sequestering of bmp in extracellular matrix
(GO:0035582)
Signal transduction involved in regulation of gene expression
(GO:0023019)
Ureteric bud development
(GO:0001657)

Other Information

Proteins

Cerberus

Genular Protein ID: 2803754980

Symbol: CER1_MOUSE

Name: Cerberus

UniProtKB Accession Codes:

O55233 O35213

Database IDs:

Citations:

PubMed ID: 9431803

Title: Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula.

PubMed ID: 9431803

DOI: 10.1016/s0925-4773(97)00125-1

PubMed ID: 9501024

Title: Murine cerberus homologue mCer-1: a candidate anterior patterning molecule.

PubMed ID: 9501024

DOI: 10.1006/dbio.1997.8812

PubMed ID: 9600941

Title: Expression of the mouse cerberus-related gene, Cerr1, suggests a role in anterior neural induction and somitogenesis.

PubMed ID: 9600941

DOI: 10.1073/pnas.95.11.6198

PubMed ID: 12431380

Title: Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks.

PubMed ID: 12431380

DOI: 10.1016/s1534-5807(02)00321-0

Sequence Information:

Length: 272
Mass: 30431
Checksum: DD0842A2619AF057
Sequence:

MHLLLVQLLV LLPLGKADLC VDGCQSQGSL SFPLLERGRR DLHVANHEEA EDKPDLFVAV 
PHLMGTSLAG EGQRQRGKML SRLGRFWKKP ETEFYPPRDV ESDHVSSGMQ AVTQPADGRK 
VERSPLQEEA KRFWHRFMFR KGPAFQGVIL PIKSHEVHWE TCRTVPFNQT IAHEDCQKVV 
VQNNLCFGKC SSIRFPGEGA DAHSFCSHCS PTKFTTVHLM LNCTSPTPVV KMVMQVEECQ 
CMVKTERGEE RLLLAGSQGS FIPGLPASKT NP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cer1

Associated with

Other Information

Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula. PubMed ID: 9431803

Murine cerberus homologue mCer-1: a candidate anterior patterning molecule. PubMed ID: 9501024

Expression of the mouse cerberus-related gene, Cerr1, suggests a role in anterior neural induction and somitogenesis. PubMed ID: 9600941

Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks. PubMed ID: 12431380

Database document:

PubMed ID: 9431803

PubMed ID: 9501024

PubMed ID: 9600941

PubMed ID: 12431380