Genular: Defining Cellular Identity and Function

Details for: Chkb

Gene ID: 12651

Symbol: Chkb

Ensembl ID: ENSMUSG00000022617

Description: choline kinase beta

Associated with

Glycerophospholipid biosynthesis
(R-MMU-1483206)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Phospholipid metabolism
(R-MMU-1483257)
Synthesis of pc
(R-MMU-1483191)
Synthesis of pe
(R-MMU-1483213)
Atp binding
(GO:0005524)
Cdp-choline pathway
(GO:0006657)
Choline kinase activity
(GO:0004103)
Cytoplasm
(GO:0005737)
Ethanolamine kinase activity
(GO:0004305)
Kinase activity
(GO:0016301)
Lipid metabolic process
(GO:0006629)
Muscle organ development
(GO:0007517)
Nucleotide binding
(GO:0000166)
Phosphatidylcholine biosynthetic process
(GO:0006656)
Phosphatidylethanolamine biosynthetic process
(GO:0006646)
Phospholipid biosynthetic process
(GO:0008654)
Phosphorylation
(GO:0016310)
Transferase activity
(GO:0016740)

Other Information

Proteins

Choline/ethanolamine kinase

Genular Protein ID: 3870570305

Symbol: CHKB_MOUSE

Name: Choline/ethanolamine kinase

UniProtKB Accession Codes:

O55229

Database IDs:

Citations:

PubMed ID: 9714798

Title: Molecular cloning of mouse choline kinase and choline/ethanolamine kinase: their sequence comparison to the respective rat homologs.

PubMed ID: 9714798

DOI: 10.1016/s0005-2760(98)00062-9

PubMed ID: 16490392

Title: Deletion and alanine mutation analyses for the formation of active homo- or hetero-dimer complexes of mouse choline kinase-alpha and -beta.

PubMed ID: 16490392

DOI: 10.1016/j.bbalip.2006.01.005

PubMed ID: 16371353

Title: A rostrocaudal muscular dystrophy caused by a defect in choline kinase beta, the first enzyme in phosphatidylcholine biosynthesis.

PubMed ID: 16371353

DOI: 10.1074/jbc.m512578200

PubMed ID: 19236939

Title: Understanding the muscular dystrophy caused by deletion of choline kinase beta in mice.

PubMed ID: 19236939

DOI: 10.1016/j.bbalip.2009.02.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 394
Mass: 45126
Checksum: A5EE79EC551D07A2
Sequence:

MAADGTGVVG GGAVGGGLPK DGLQDAKCPE PIPNRRRASS LSRDAQRRAY QWCREYLGGA 
WRRARPEELS VCPVSGGLSN LLFRCSLPNH VPSVGGEPRE VLLRLYGAIL QGVDSLVLES 
VMFAILAERS LGPQLYGVFP EGRLEQYLPS RPLKTQELRD PVLSGAIATR MARFHGMEMP 
FTKEPRWLFG TMERYLKQIQ DLPSTSLPQM NLVEMYSLKD EMNSLRKLLD DTPSPVVFCH 
NDIQEGNILL LSEPDSDDNL MLVDFEYSSY NYRGFDIGNH FCEWVYDYTY EEWPFYKARP 
TDYPTREQQL HFIRHYLAEV QKGEILSEEE QKKREEELLL EISRYSLASH FFWGLWSTLQ 
ASMSTIEFGY LEYAQSRFQF YFQQKGQLTS SPSS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Chkb

Associated with

Other Information

Molecular cloning of mouse choline kinase and choline/ethanolamine kinase: their sequence comparison to the respective rat homologs. PubMed ID: 9714798

Deletion and alanine mutation analyses for the formation of active homo- or hetero-dimer complexes of mouse choline kinase-alpha and -beta. PubMed ID: 16490392

A rostrocaudal muscular dystrophy caused by a defect in choline kinase beta, the first enzyme in phosphatidylcholine biosynthesis. PubMed ID: 16371353