Details for: Chi3l1

Gene ID: 12654

Symbol: Chi3l1

Ensembl ID: ENSMUSG00000064246

Description: chitinase 3 like 1

Associated with

Other Information

Genular Protein ID: 3457161667

Symbol: CH3L1_MOUSE

Name: Chitinase-3-like protein 1

UniProtKB Accession Codes:

Q61362 B0FEU7 D3Z2P2 Q3U291 Q4FJW9 Q8BKL8 Q99J84

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CAZy 1 CCDS 2 CDD 1 CTD 1 ChEBI 5 ChiTaRS 1 DNASU 1 EMBL 9 Ensembl 3 ExpressionAtlas 1 GO 21 Gene3D 2 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 1 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 jPOST 1

Citations:

PubMed ID: 7970700

Title: neu and ras initiate murine mammary tumors that share genetic markers generally absent in c-myc and int-2-initiated tumors.

PubMed ID: 7970700

PubMed ID: 19041398

Title: Cloning, expression, characterization and crystallization of BRP39, a signalling glycoprotein expressed during mammary gland apoptosis.

PubMed ID: 19041398

DOI: 10.1016/j.pep.2008.11.001

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16472595

Title: Chitinase 3-like-1 exacerbates intestinal inflammation by enhancing bacterial adhesion and invasion in colonic epithelial cells.

PubMed ID: 16472595

DOI: 10.1053/j.gastro.2005.12.007

PubMed ID: 19414556

Title: Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis.

PubMed ID: 19414556

DOI: 10.1084/jem.20081271

PubMed ID: 20558631

Title: The chitinase-like proteins breast regression protein-39 and YKL-40 regulate hyperoxia-induced acute lung injury.

PubMed ID: 20558631

DOI: 10.1164/rccm.200912-1793oc

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21546314

Title: Carbohydrate-binding motif in chitinase 3-like 1 (CHI3L1/YKL-40) specifically activates Akt signaling pathway in colonic epithelial cells.

PubMed ID: 21546314

DOI: 10.1016/j.clim.2011.04.007

PubMed ID: 22817986

Title: Chitinase 3-like-1 promotes Streptococcus pneumoniae killing and augments host tolerance to lung antibacterial responses.

PubMed ID: 22817986

DOI: 10.1016/j.chom.2012.05.017

PubMed ID: 21866546

Title: Induction of proinflammatory mediators by CHI3L1 is reduced by chitin treatment: decreased tumor metastasis in a breast cancer model.

PubMed ID: 21866546

DOI: 10.1002/ijc.26379

Sequence Information:

  • Length: 389
  • Mass: 43893
  • Checksum: 9E7D66069B233834
  • Sequence:
    • MHTSTEARMG MRAALTGFAV LMLLQSCSAY KLVCYFTSWS QYREGVGSFL PDAIQPFLCT 
HIIYSFANIS SDNMLSTWEW NDESNYDKLN KLKTRNTNLK TLLSVGGWKF GEKRFSEIAS 
NTERRTAFVR SVAPFLRSYG FDGLDLAWLY PRLRDKQYFS TLIKELNAEF TKEVQPGREK 
LLLSAALSAG KVAIDTGYDI AQIAQHLDFI NLMTYDFHGV WRQITGHHSP LFQGQKDTRF 
DRYSNVNYAV QYMIRLGAQA SKLLMGIPTF GKSFTLASSE NQLGAPISGE GLPGRFTKEA 
GTLAYYEICD FLKGAEVHRL SNEKVPFATK GNQWVGYEDK ESVKNKVGFL KEKKLAGAMV 
WALDLDDFQG TCQPKEFFPL TNAIKDALA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.