Details for: Chl1

Gene ID: 12661

Symbol: Chl1

Ensembl ID: ENSMUSG00000030077

Description: cell adhesion molecule L1-like

Associated with

Other Information

Genular Protein ID: 2332121581

Symbol: NCHL1_MOUSE

Name: Neural cell adhesion molecule L1-like protein

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8921253

Title: Structural features of a close homologue of L1 (CHL1) in the mouse: a new member of the L1 family of neural recognition molecules.

PubMed ID: 8921253

DOI: 10.1111/j.1460-9568.1996.tb01306.x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12391163

Title: Misguided axonal projections, neural cell adhesion molecule 180 mRNA upregulation, and altered behavior in mice deficient for the close homolog of L1.

PubMed ID: 12391163

DOI: 10.1128/mcb.22.22.7967-7981.2002

PubMed ID: 10103075

Title: The close homologue of the neural adhesion molecule L1 (CHL1): patterns of expression and promotion of neurite outgrowth by heterophilic interactions.

PubMed ID: 10103075

DOI: 10.1046/j.1460-9568.1999.00496.x

PubMed ID: 10022583

Title: Prevention of neuronal cell death by neural adhesion molecules L1 and CHL1.

PubMed ID: 10022583

DOI: 10.1002/(sici)1097-4695(19990215)38:3<428::aid-neu10>3.0.co;2-6

PubMed ID: 14659567

Title: Mice deficient for the close homologue of the neural adhesion cell L1 (CHL1) display alterations in emotional reactivity and motor coordination.

PubMed ID: 14659567

DOI: 10.1016/s0166-4328(03)00114-1

PubMed ID: 12812975

Title: CALL interrupted in a patient with non-specific mental retardation: gene dosage-dependent alteration of murine brain development and behavior.

PubMed ID: 12812975

DOI: 10.1093/hmg/ddg165

PubMed ID: 12721290

Title: Close homolog of L1 is an enhancer of integrin-mediated cell migration.

PubMed ID: 12721290

DOI: 10.1074/jbc.m303084200

PubMed ID: 14761956

Title: Ectodomain shedding of the neural recognition molecule CHL1 by the metalloprotease-disintegrin ADAM8 promotes neurite outgrowth and suppresses neuronal cell death.

PubMed ID: 14761956

DOI: 10.1074/jbc.m400560200

PubMed ID: 15504324

Title: Close homolog of L1 modulates area-specific neuronal positioning and dendrite orientation in the cerebral cortex.

PubMed ID: 15504324

DOI: 10.1016/j.neuron.2004.10.016

PubMed ID: 16623841

Title: Enhanced perisomatic inhibition and impaired long-term potentiation in the CA1 region of juvenile CHL1-deficient mice.

PubMed ID: 16623841

DOI: 10.1111/j.1460-9568.2006.04710.x

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 29325091

Title: alpha-secretase ADAM10 physically interacts with beta-secretase BACE1 in neurons and regulates CHL1 proteolysis.

PubMed ID: 29325091

DOI: 10.1093/jmcb/mjy001

Sequence Information:

  • Length: 1209
  • Mass: 135074
  • Checksum: 2C689475920AB84C
  • Sequence:
  • MMELPLCGRG LILSLIFLLL KLSAAEIPLS VQQVPTIVKQ SYVQVAFPFD EYFQIECEAK 
    GNPEPIFSWT KDDKPFDLSD PRIIAANNSG TFKIPNEGHI SHFQGKYRCF ASNRLGTAVS 
    EEIEFIVPGV PKFPKEKIEP IDVEEGDSIV LPCNPPKGLP PLHIYWMNIE LEHIEQDERV 
    YMSQRGDLYF ANVEENDSRN DYCCFAAFPK LRTIVQKMPM KLTVNSSNSI KQRKPKLLLP 
    PAQMGSLSAK TVLKGDTLLL ECFAEGLPTP HIQWSKPGSE LPEGRATIEV HEKTLKIENI 
    SYQDRGNYRC TANNLLGKAS HDFHVTVEEP PRWKKKPQSA VYSTGSSGIL LCEAEGEPQP 
    TIKWRLNGLP IEKHPFPGDF MFPREISFTN LLPNHTGVYQ CEASNIHGTI LANANIDVID 
    VIPLIKTKNE ENYATVVGYS AFLHCEYFAS PKATVVWEVA DETHPLEGDR YHTHENGTLE 
    IYRTTEEDAG SYSCWVDNAM GKAVITANLD IRNATKLRVS PKNPRIPKSH VLELYCESQC 
    DSHLKHSLKL SWSKDGEAFE MNGTEDGRIV IDGAYLTISN ITAEDQGVYS CSAQTSLDST 
    SEKTQVTVLG VPDPPGNLHL SERQNRSVRL SWEAGDDHNS KISEYIVEFE GNREEPGKWE 
    ELTRVQGEET DVVLSLAPYV RYQFRVTAVN EVGRSHASLP SDHHETPPAA PDKNPQNIRV 
    QASQPKEMII KWEPLKSMEQ NGPGLEYKVS WKPQGAPEEW EEEIVTNHTL RVMTPTVYAP 
    YDVKVQAINQ LGSSPDPQPV TLYSGEDYPS TAPVIQRVDV MNSTLVKVTW SSIPKETVHG 
    LLRGYQINWW KTKSLLDGRT HPKEVNILRF SGQRNSGMVP SLDPFSEFHL TVLAYNSKGA 
    GPESEPYIFQ TPEGVPEQPS FLKVIKVDKD TATLSWGLPK KLNGNLTGYL LQYQIINDTY 
    ELGELNEINV TTPSKSSWHL SNLNSTTKYK FYLRACTSRG CGKPISEEGA TLGEGSKGIR 
    KITEGVNVTQ KIHPVEVLVP GAEHIVHLMT KNWGDNDSIF QDVIETRGRE YAGLYDDIST 
    QGWFIGLMCA IALLTLILLT ICFVKRNRGG KYSVKEKEDL HPDPEVQSAK DETFGEYSDS 
    DEKPLKGSLR SLNRNMQPTE SADSLVEYGE GDQSIFNEDG SFIGAYTGAK EKGSVESNGS 
    STATFPLRA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.