Details for: CNTF

Gene ID: 1270

Symbol: CNTF

Ensembl ID: ENSG00000242689

Description: ciliary neurotrophic factor

Associated with

Other Information

Genular Protein ID: 2214813036

Symbol: CNTF_HUMAN

Name: Ciliary neurotrophic factor

UniProtKB Accession Codes:

P26441 B2RAB2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 DIP 1 DNASU 1 DisGeNET 1 EMBL 10 Ensembl 1 EvolutionaryTrace 1 GO 22 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 2 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 neXtProt 1

Citations:

PubMed ID: 1861138

Title: Recombinant human and rat ciliary neurotrophic factors.

PubMed ID: 1861138

DOI: 10.1111/j.1471-4159.1991.tb08250.x

PubMed ID: 1915374

Title: Cloning and expression of human ciliary neurotrophic factor.

PubMed ID: 1915374

DOI: 10.1111/j.1432-1033.1991.tb16286.x

PubMed ID: 1840538

Title: Sequence and structural organization of the human gene encoding ciliary neurotrophic factor.

PubMed ID: 1840538

DOI: 10.1016/0378-1119(91)90089-t

PubMed ID: 1883844

Title: Expression and characterization of recombinant human ciliary neurotrophic factor from Escherichia coli.

PubMed ID: 1883844

DOI: 10.1016/0167-4781(91)90038-n

PubMed ID: 8075647

Title: A null mutation in the human CNTF gene is not causally related to neurological diseases.

PubMed ID: 8075647

DOI: 10.1038/ng0594-79

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7796798

Title: Crystal structure of dimeric human ciliary neurotrophic factor determined by MAD phasing.

PubMed ID: 7796798

DOI: 10.1002/j.1460-2075.1995.tb07269.x

PubMed ID: 10391209

Title: Characterization of single-nucleotide polymorphisms in coding regions of human genes.

PubMed ID: 10391209

DOI: 10.1038/10290

Sequence Information:

  • Length: 200
  • Mass: 22931
  • Checksum: EDD9D895BDA6F35A
  • Sequence:
    • MAFTEHSPLT PHRRDLCSRS IWLARKIRSD LTALTESYVK HQGLNKNINL DSADGMPVAS 
TDQWSELTEA ERLQENLQAY RTFHVLLARL LEDQQVHFTP TEGDFHQAIH TLLLQVAAFA 
YQIEELMILL EYKIPRNEAD GMPINVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRFIS 
SHQTGIPARG SHYIANNKKM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.