Genular: Defining Cellular Identity and Function

Details for: Ckb

Gene ID: 12709

Symbol: Ckb

Ensembl ID: ENSMUSG00000001270

Description: creatine kinase, brain

Associated with

Creatine metabolism
(R-MMU-71288)
Metabolism
(R-MMU-1430728)
Metabolism of amino acids and derivatives
(R-MMU-71291)
Rho gtpase cycle
(R-MMU-9012999)
Rnd3 gtpase cycle
(R-MMU-9696264)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Atp binding
(GO:0005524)
Catalytic activity
(GO:0003824)
Creatine kinase activity
(GO:0004111)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dendrite
(GO:0030425)
Extracellular space
(GO:0005615)
Futile creatine cycle
(GO:0140651)
Intracellular chloride ion homeostasis
(GO:0030644)
Kinase activity
(GO:0016301)
Membrane
(GO:0016020)
Mitochondrion
(GO:0005739)
Myelin sheath
(GO:0043209)
Neuronal cell body
(GO:0043025)
Nucleotide binding
(GO:0000166)
Phosphocreatine biosynthetic process
(GO:0046314)
Phosphorylation
(GO:0016310)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Transferase activity
(GO:0016740)
Transferase activity, transferring phosphorus-containing groups
(GO:0016772)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

B-CK

Genular Protein ID: 2322353846

Symbol: KCRB_MOUSE

Name: B-CK

UniProtKB Accession Codes:

Q04447 Q3KQP4 Q3TKI3 Q3U5P5 Q3UF71 Q9CXK6

Database IDs:

Citations:

PubMed ID: 1740343

Title: Genetic variability of the murine creatine kinase B gene locus and related pseudogenes in different inbred strains of mice.

PubMed ID: 1740343

DOI: 10.1016/0888-7543(92)90383-4

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3641191

Title: The 3' non-coding region of the mouse brain B creatine kinase mRNA: a sequence with exceptional homology among species.

PubMed ID: 3641191

DOI: 10.1093/nar/14.21.8690

PubMed ID: 15648052

Title: Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol.

PubMed ID: 15648052

DOI: 10.1002/pmic.200401066

PubMed ID: 16800626

Title: Endogenously nitrated proteins in mouse brain: links to neurodegenerative disease.

PubMed ID: 16800626

DOI: 10.1021/bi060474w

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.t500041-mcp200

PubMed ID: 18566107

Title: HMSN/ACC truncation mutations disrupt brain-type creatine kinase-dependant activation of K+/Cl- co-transporter 3.

PubMed ID: 18566107

DOI: 10.1093/hmg/ddn172

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 33597756

Title: Creatine kinase B controls futile creatine cycling in thermogenic fat.

PubMed ID: 33597756

DOI: 10.1038/s41586-021-03221-y

Sequence Information:

Length: 381
Mass: 42713
Checksum: D901C5653054A490
Sequence:

MPFSNSHNTQ KLRFPAEDEF PDLSSHNNHM AKVLTPELYA ELRAKCTPSG FTLDDAIQTG 
VDNPGHPYIM TVGAVAGDEE SYDVFKDLFD PIIEERHGGY QPSDEHKTDL NPDNLQGGDD 
LDPNYVLSSR VRTGRSIRGF CLPPHCSRGE RRAIEKLAVE ALSSLDGDLS GRYYALKSMT 
EAEQQQLIDD HFLFDKPVSP LLLASGMARD WPDARGIWHN DNKTFLVWIN EEDHLRVISM 
QKGGNMKEVF TRFCTGLTQI ETLFKSKNYE FMWNPHLGYI LTCPSNLGTG LRAGVHIKLP 
HLGKHEKFSE VLKRLRLQKR GTGGVDTAAV GGVFDVSNAD RLGFSEVELV QMVVDGVKLL 
IEMEQRLEQG QAIDDLMPAQ K

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ckb

Associated with

Other Information

Genetic variability of the murine creatine kinase B gene locus and related pseudogenes in different inbred strains of mice. PubMed ID: 1740343

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The 3' non-coding region of the mouse brain B creatine kinase mRNA: a sequence with exceptional homology among species. PubMed ID: 3641191

Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol. PubMed ID: 15648052

Endogenously nitrated proteins in mouse brain: links to neurodegenerative disease. PubMed ID: 16800626

Comprehensive identification of phosphorylation sites in postsynaptic density preparations. PubMed ID: 16452087

HMSN/ACC truncation mutations disrupt brain-type creatine kinase-dependant activation of K+/Cl- co-transporter 3. PubMed ID: 18566107

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. PubMed ID: 18034455

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Creatine kinase B controls futile creatine cycling in thermogenic fat. PubMed ID: 33597756