CNTFR | ENSG00000122756 | NCBI 1271

Details for: CNTFR

Gene ID: 1271

Symbol: CNTFR

Ensembl ID: ENSG00000122756

Description: ciliary neurotrophic factor receptor

Associated with

Cytokine signaling in immune system
(R-HSA-1280215)
Il-6-type cytokine receptor ligand interactions
(R-HSA-6788467)
Immune system
(R-HSA-168256)
Interleukin-6 family signaling
(R-HSA-6783589)
Signaling by interleukins
(R-HSA-449147)
Apical plasma membrane
(GO:0016324)
Brainstem development
(GO:0003360)
Ciliary neurotrophic factor-mediated signaling pathway
(GO:0070120)
Ciliary neurotrophic factor receptor activity
(GO:0004897)
Ciliary neurotrophic factor receptor complex
(GO:0070110)
Cntfr-clcf1 complex
(GO:0097059)
Cytokine binding
(GO:0019955)
Cytokine receptor activity
(GO:0004896)
External side of plasma membrane
(GO:0009897)
Extrinsic component of membrane
(GO:0019898)
Motor neuron apoptotic process
(GO:0097049)
Negative regulation of motor neuron apoptotic process
(GO:2000672)
Negative regulation of neuron apoptotic process
(GO:0043524)
Nervous system development
(GO:0007399)
Plasma membrane
(GO:0005886)
Positive regulation of cell population proliferation
(GO:0008284)
Protein binding
(GO:0005515)
Sex differentiation
(GO:0007548)
Signaling receptor binding
(GO:0005102)
Signal transduction
(GO:0007165)
Skeletal muscle organ development
(GO:0060538)
Suckling behavior
(GO:0001967)

Other Information

Proteins

Ciliary neurotrophic factor receptor subunit alpha

Genular Protein ID: 3441002583

Symbol: CNTFR_HUMAN

Name: Ciliary neurotrophic factor receptor subunit alpha

UniProtKB Accession Codes:

P26992 Q5U050

Database IDs:

Citations:

PubMed ID: 1648265

Title: The receptor for ciliary neurotrophic factor.

PubMed ID: 1648265

DOI: 10.1126/science.1648265

PubMed ID: 7774913

Title: Genomic organization and chromosomal localization of the human and mouse genes encoding the alpha receptor component for ciliary neurotrophic factor.

PubMed ID: 7774913

DOI: 10.1016/0888-7543(95)80121-2

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19386761

Title: Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor alpha/WSX-1/gp130.

PubMed ID: 19386761

DOI: 10.1091/mbc.e09-02-0168

PubMed ID: 26858303

Title: Cytokine-like factor 1, an essential facilitator of cardiotrophin-like cytokine:ciliary neurotrophic factor receptor alpha signaling and sorLA-mediated turnover.

PubMed ID: 26858303

DOI: 10.1128/mcb.00917-15

PubMed ID: 12707266

Title: Solution structure of the C-terminal domain of the ciliary neurotrophic factor (CNTF) receptor and ligand free associations among components of the CNTF receptor complex.

PubMed ID: 12707266

DOI: 10.1074/jbc.m301976200

Sequence Information:

Length: 372
Mass: 40633
Checksum: B2F3F73DE8F8750E
Sequence:

MAAPVPWACC AVLAAAAAVV YAQRHSPQEA PHVQYERLGS DVTLPCGTAN WDAAVTWRVN 
GTDLAPDLLN GSQLVLHGLE LGHSGLYACF HRDSWHLRHQ VLLHVGLPPR EPVLSCRSNT 
YPKGFYCSWH LPTPTYIPNT FNVTVLHGSK IMVCEKDPAL KNRCHIRYMH LFSTIKYKVS 
ISVSNALGHN ATAITFDEFT IVKPDPPENV VARPVPSNPR RLEVTWQTPS TWPDPESFPL 
KFFLRYRPLI LDQWQHVELS DGTAHTITDA YAGKEYIIQV AAKDNEIGTW SDWSVAAHAT 
PWTEEPRHLT TEAQAAETTT STTSSLAPPP TTKICDPGEL GSGGGPSAPF LVSVPITLAL 
AAAAATASSL LI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CNTFR

Associated with

Other Information

The receptor for ciliary neurotrophic factor. PubMed ID: 1648265

Genomic organization and chromosomal localization of the human and mouse genes encoding the alpha receptor component for ciliary neurotrophic factor. PubMed ID: 7774913

DNA sequence and analysis of human chromosome 9. PubMed ID: 15164053

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor alpha/WSX-1/gp130. PubMed ID: 19386761

Cytokine-like factor 1, an essential facilitator of cardiotrophin-like cytokine:ciliary neurotrophic factor receptor alpha signaling and sorLA-mediated turnover. PubMed ID: 26858303

Solution structure of the C-terminal domain of the ciliary neurotrophic factor (CNTF) receptor and ligand free associations among components of the CNTF receptor complex. PubMed ID: 12707266