Genular: Defining Cellular Identity and Function

Details for: Coro1a

Gene ID: 12721

Symbol: Coro1a

Ensembl ID: ENSMUSG00000030707

Description: coronin, actin binding protein 1A

Associated with

Actin binding
(GO:0003779)
Actin cytoskeleton
(GO:0015629)
Actin cytoskeleton organization
(GO:0030036)
Actin filament
(GO:0005884)
Actin filament binding
(GO:0051015)
Actin filament organization
(GO:0007015)
Actin monomer binding
(GO:0003785)
Axon
(GO:0030424)
Calcium ion transport
(GO:0006816)
Cell-cell junction
(GO:0005911)
Cell-substrate adhesion
(GO:0031589)
Cell leading edge
(GO:0031252)
Cell migration
(GO:0016477)
Cellular response to interleukin-4
(GO:0071353)
Cortical actin cytoskeleton
(GO:0030864)
Cytoplasm
(GO:0005737)
Cytoplasmic vesicle
(GO:0031410)
Cytoskeletal protein binding
(GO:0008092)
Cytoskeleton
(GO:0005856)
Early endosome
(GO:0005769)
Early endosome to recycling endosome transport
(GO:0061502)
Epithelial cell migration
(GO:0010631)
Establishment of localization in cell
(GO:0051649)
Glutamatergic synapse
(GO:0098978)
Homeostasis of number of cells within a tissue
(GO:0048873)
Identical protein binding
(GO:0042802)
Immunological synapse
(GO:0001772)
Lamellipodium
(GO:0030027)
Leukocyte chemotaxis
(GO:0030595)
Membrane
(GO:0016020)
Myosin heavy chain binding
(GO:0032036)
Natural killer cell degranulation
(GO:0043320)
Negative regulation of actin nucleation
(GO:0051126)
Negative regulation of neuron apoptotic process
(GO:0043524)
Negative regulation of vesicle fusion
(GO:0031339)
Nerve growth factor signaling pathway
(GO:0038180)
Neuron apoptotic process
(GO:0051402)
Phagocytic cup
(GO:0001891)
Phagocytic vesicle
(GO:0045335)
Phagocytosis
(GO:0006909)
Phagolysosome assembly
(GO:0001845)
Phosphatidylinositol 3-kinase binding
(GO:0043548)
Plasma membrane
(GO:0005886)
Positive chemotaxis
(GO:0050918)
Positive regulation of t cell activation
(GO:0050870)
Positive regulation of t cell migration
(GO:2000406)
Positive regulation of t cell proliferation
(GO:0042102)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Regulation of actin cytoskeleton organization
(GO:0032956)
Regulation of actin filament polymerization
(GO:0030833)
Regulation of actin polymerization or depolymerization
(GO:0008064)
Regulation of cell shape
(GO:0008360)
Regulation of release of sequestered calcium ion into cytosol
(GO:0051279)
Response to cytokine
(GO:0034097)
Stereocilium tip
(GO:0032426)
Synapse
(GO:0045202)
T cell activation
(GO:0042110)
T cell homeostasis
(GO:0043029)
T cell migration
(GO:0072678)
T cell proliferation
(GO:0042098)
Thymocyte migration
(GO:0072679)
Uropod organization
(GO:0032796)
Vesicle fusion
(GO:0006906)

Other Information

Proteins

Coronin-1A

Genular Protein ID: 3901801331

Symbol: COR1A_MOUSE

Name: Coronin-1A

UniProtKB Accession Codes:

O89053 Q7TMU0 Q9R1Y8 Q9R288

Database IDs:

Citations:

PubMed ID: 9778037

Title: Definition of family of coronin-related proteins conserved between humans and mice: close genetic linkage between coronin-2 and CD45-associated protein.

PubMed ID: 9778037

DOI: 10.1089/dna.1998.17.779

PubMed ID: 10338208

Title: A coat protein on phagosomes involved in the intracellular survival of mycobacteria.

PubMed ID: 10338208

DOI: 10.1016/s0092-8674(00)80754-0

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9798653

Title: Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis.

PubMed ID: 9798653

DOI: 10.1016/s0161-5890(98)00031-5

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23100250

Title: Constitutive turnover of phosphorylation at Thr-412 of human p57/coronin-1 regulates the interaction with actin.

PubMed ID: 23100250

DOI: 10.1074/jbc.m112.349829

PubMed ID: 16172398

Title: A conserved trimerization motif controls the topology of short coiled coils.

PubMed ID: 16172398

DOI: 10.1073/pnas.0502390102

PubMed ID: 16407068

Title: The crystal structure of murine coronin-1: a regulator of actin cytoskeletal dynamics in lymphocytes.

PubMed ID: 16407068

DOI: 10.1016/j.str.2005.09.013

Sequence Information:

Length: 461
Mass: 50989
Checksum: 9098F53757C5318D
Sequence:

MSRQVVRSSK FRHVFGQPAK ADQCYEDVRV SQTTWDSGFC AVNPKFMALI CEASGGGAFL 
VLPLGKTGRV DKNVPLVCGH TAPVLDIAWC PHNDNVIASG SEDCTVMVWE IPDGGLVLPL 
REPVITLEGH TKRVGIVAWH PTAQNVLLSA GCDNVILVWD VGTGAAVLTL GPDVHPDTIY 
SVDWSRDGAL ICTSCRDKRV RVIEPRKGTV VAEKDRPHEG TRPVHAVFVS EGKILTTGFS 
RMSERQVALW DTKHLEEPLS LQELDTSSGV LLPFFDPDTN IVYLCGKGDS SIRYFEITSE 
APFLHYLSMF SSKESQRGMG YMPKRGLEVN KCEIARFYKL HERKCEPIAM TVPRKSDLFQ 
EDLYPPTAGP DPALTAEEWL GGRDAGPLLI SLKDGYVPPK SRELRVNRGL DSARRRATPE 
PSGTPSSDTV SRLEEDVRNL NAIVQKLQER LDRLEETVQA K

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Coro1a

Associated with

Other Information

Definition of family of coronin-related proteins conserved between humans and mice: close genetic linkage between coronin-2 and CD45-associated protein. PubMed ID: 9778037

A coat protein on phagosomes involved in the intracellular survival of mycobacteria. PubMed ID: 10338208

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis. PubMed ID: 9798653

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Constitutive turnover of phosphorylation at Thr-412 of human p57/coronin-1 regulates the interaction with actin. PubMed ID: 23100250

A conserved trimerization motif controls the topology of short coiled coils. PubMed ID: 16172398

The crystal structure of murine coronin-1: a regulator of actin cytoskeletal dynamics in lymphocytes. PubMed ID: 16407068