Details for: Cldn2

Gene ID: 12738

Symbol: Cldn2

Ensembl ID: ENSMUSG00000047230

Description: claudin 2

Associated with

Other Information

Genular Protein ID: 465487392

Symbol: CLD2_MOUSE

Name: Claudin-2

UniProtKB Accession Codes:

O88552

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 Ensembl 1 ExpressionAtlas 1 GO 9 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 4 KEGG 1 MGI 1 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRINTS 2 PRO 1 PROSITE 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 2 SAM 1 SMR 1 STRING 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 9647647

Title: Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin.

PubMed ID: 9647647

DOI: 10.1083/jcb.141.7.1539

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10508613

Title: Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions.

PubMed ID: 10508613

DOI: 10.1016/s0960-9822(99)80452-7

PubMed ID: 10562289

Title: Manner of interaction of heterogeneous claudin species within and between tight junction strands.

PubMed ID: 10562289

DOI: 10.1083/jcb.147.4.891

PubMed ID: 10601346

Title: Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins.

PubMed ID: 10601346

DOI: 10.1083/jcb.147.6.1351

PubMed ID: 11934881

Title: Cloning of the human claudin-2 5'-flanking region revealed a TATA-less promoter with conserved binding sites in mouse and human for caudal-related homeodomain proteins and hepatocyte nuclear factor-1alpha.

PubMed ID: 11934881

DOI: 10.1074/jbc.m110261200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 32149733

Title: Claudin-2 deficiency associates with hypercalciuria in mice and human kidney stone disease.

PubMed ID: 32149733

DOI: 10.1172/jci127750

Sequence Information:

  • Length: 230
  • Mass: 24484
  • Checksum: 38A7C074A1E0D5D2
  • Sequence:
    • MASLGVQLVG YILGLLGLLG TSIAMLLPNW RTSSYVGASI VTAVGFSKGL WMECATHSTG 
ITQCDIYSTL LGLPADIQAA QAMMVTSSAM SSLACIISVV GMRCTVFCQD SRAKDRVAVV 
GGVFFILGGI LGFIPVAWNL HGILRDFYSP LVPDSMKFEI GEALYLGIIS ALFSLVAGVI 
LCFSCSPQGN RTNYYDGYQA QPLATRSSPR SAQQPKAKSE FNSYSLTGYV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.