Details for: Cldn4

Gene ID: 12740

Symbol: Cldn4

Ensembl ID: ENSMUSG00000047501

Description: claudin 4

Associated with

Other Information

Genular Protein ID: 3477036252

Symbol: CLD4_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9334247

Title: Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo.

PubMed ID: 9334247

DOI: 10.1074/jbc.272.42.26652

PubMed ID: 9892664

Title: Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands.

PubMed ID: 9892664

DOI: 10.1073/pnas.96.2.511

PubMed ID: 10601346

Title: Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins.

PubMed ID: 10601346

DOI: 10.1083/jcb.147.6.1351

PubMed ID: 16236711

Title: EphA2 phosphorylates the cytoplasmic tail of Claudin-4 and mediates paracellular permeability.

PubMed ID: 16236711

DOI: 10.1074/jbc.m503786200

PubMed ID: 20921420

Title: Claudin-4 forms paracellular chloride channel in the kidney and requires claudin-8 for tight junction localization.

PubMed ID: 20921420

DOI: 10.1073/pnas.1009399107

PubMed ID: 25831548

Title: KLHL3 regulates paracellular chloride transport in the kidney by ubiquitination of claudin-8.

PubMed ID: 25831548

DOI: 10.1073/pnas.1421441112

Sequence Information:

  • Length: 210
  • Mass: 22339
  • Checksum: 3B6D571EC71D6564
  • Sequence:
  • MASMGLQVLG ISLAVLGWLG IILSCALPMW RVTAFIGSNI VTAQTSWEGL WMNCVVQSTG 
    QMQCKMYDSM LALPQDLQAA RALMVISIIV GALGMLLSVV GGKCTNCMED ETVKAKIMIT 
    AGAVFIVASM LIMVPVSWTA HNVIRDFYNP MVASGQKREM GASLYVGWAA SGLLLLGGGL 
    LCCSCPPRSN DKPYSAKYSA ARSVPASNYV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.