Details for: Cln3
Associated with
Other Information
Genular Protein ID: 690455046
Symbol: CLN3_MOUSE
Name: Protein CLN3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8812504
Title: Isolation and chromosomal mapping of a mouse homolog of the Batten disease gene CLN3.
PubMed ID: 8812504
PubMed ID: 9151313
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10440905
Title: A mouse gene knockout model for juvenile ceroid-lipofuscinosis (Batten disease).
PubMed ID: 10440905
DOI: 10.1002/(sici)1097-4547(19990815)57:4<551::aid-jnr15>3.3.co;2-i
PubMed ID: 10191118
Title: CLN3 defines a novel antiapoptotic pathway operative in neurodegeneration and mediated by ceramide.
PubMed ID: 10191118
PubMed ID: 10527801
Title: Targeted disruption of the Cln3 gene provides a mouse model for Batten disease. The Batten Mouse Model Consortium [corrected].
PubMed ID: 10527801
PubMed ID: 11590129
Title: CLN3 protein is targeted to neuronal synapses but excluded from synaptic vesicles: new clues to Batten disease.
PubMed ID: 11590129
PubMed ID: 12374761
Title: Cln3(Deltaex7/8) knock-in mice with the common JNCL mutation exhibit progressive neurologic disease that begins before birth.
PubMed ID: 12374761
PubMed ID: 15588329
Title: Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosis.
PubMed ID: 15588329
PubMed ID: 16714284
Title: Autophagy is disrupted in a knock-in mouse model of juvenile neuronal ceroid lipofuscinosis.
PubMed ID: 16714284
PubMed ID: 17189291
Title: Neuronal vulnerability of CLN3 deletion to calcium-induced cytotoxicity is mediated by calsenilin.
PubMed ID: 17189291
DOI: 10.1093/hmg/ddl466
PubMed ID: 17855597
Title: A knock-in reporter model of Batten disease.
PubMed ID: 17855597
PubMed ID: 18621045
Title: Novel interactions of CLN3 protein link Batten disease to dysregulation of fodrin-Na+, K+ ATPase complex.
PubMed ID: 18621045
PubMed ID: 17962032
Title: Phenotypic characterization of a mouse model of juvenile neuronal ceroid lipofuscinosis.
PubMed ID: 17962032
PubMed ID: 19941651
Title: Novel interactions of CLN5 support molecular networking between neuronal ceroid lipofuscinosis proteins.
PubMed ID: 19941651
PubMed ID: 19144319
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
PubMed ID: 19144319
PubMed ID: 19284480
Title: Altered arginine metabolism in the central nervous system (CNS) of the Cln3-/- mouse model of juvenile Batten disease.
PubMed ID: 19284480
PubMed ID: 20219947
Title: Osmoregulation of ceroid neuronal lipofuscinosis type 3 in the renal medulla.
PubMed ID: 20219947
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 24227717
Title: CLN3 loss disturbs membrane microdomain properties and protein transport in brain endothelial cells.
PubMed ID: 24227717
PubMed ID: 24792215
Title: CLN3 deficient cells display defects in the ARF1-Cdc42 pathway and actin-dependent events.
PubMed ID: 24792215
PubMed ID: 26450516
Title: Photoreceptor phagosome processing defects and disturbed autophagy in retinal pigment epithelium of Cln3Deltaex1-6 mice modelling juvenile neuronal ceroid lipofuscinosis (Batten disease).
PubMed ID: 26450516
DOI: 10.1093/hmg/ddv406
PubMed ID: 25878248
Title: Unbiased Cell-based Screening in a Neuronal Cell Model of Batten Disease Highlights an Interaction between Ca2+ Homeostasis, Autophagy, and CLN3 Protein Function.
PubMed ID: 25878248
PubMed ID: 29135436
Title: Defective synaptic transmission causes disease signs in a mouse model of juvenile neuronal ceroid lipofuscinosis.
PubMed ID: 29135436
DOI: 10.7554/elife.28685
PubMed ID: 29780879
Title: Altered Cerebellar Short-Term Plasticity but No Change in Postsynaptic AMPA-Type Glutamate Receptors in a Mouse Model of Juvenile Batten Disease.
PubMed ID: 29780879
Sequence Information:
- Length: 438
- Mass: 47657
- Checksum: 2A06D2CE4728C1AC
- Sequence:
MGSSAGSWRR LEDSEREETD SEPQAPRLDS RSVLWKNAVG FWILGLCNNF SYVVMLSAAH DILKQEQASG NQSHVEPGPT PTPHNSSSRF DCNSISTAAV LLADILPTLV IKLLAPLGLH LLPYSPRVLV SGVCSAGSFV LVAFSQSVGL SLCGVVLASI SSGLGEVTFL SLTAFYPSAV ISWWSSGTGG AGLLGSLSYL GLTQAGLSPQ HTLLSMLGIP VLLLASYFLL LTSPEPLDPG GENEAETAAR QPLIGTETPE SKPGASWDLS LQERWTVFKG LLWYIIPLVL VYFAEYFINQ GLFELLFFRN TSLSHAQQYR WYQMLYQAGV FASRSSLQCC RIRFTWVLAL LQCLNLALLL ADVCLNFLPS IYLIFIIILY EGLLGGAAYV NTFHNIALET SDKHREFAME AACISDTLGI SLSGVLALPL HDFLCHLP
Genular Protein ID: 760473942
Symbol: Q6PAH4_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19144319
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
PubMed ID: 19144319
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
Sequence Information:
- Length: 414
- Mass: 45173
- Checksum: 44326AE03A54586D
- Sequence:
MGSSAGSWRR LEDSEREETD SEPQAPRLDS RSVLWKNAVG FWILGLCNNF SYVVMLSAAH DILKQEQASG NQSHAVLLAD ILPTLVIKLL APLGLHLLPY SPRVLVSGVC SAGSFVLVAF SQSVGLSLCG VVLASISSGL GEVTFLSLTA FYPSAVISWW SSGTGGAGLL GSLSYLGLTQ AGLSPQHTLL SMLGIPVLLL ASYFLLLTSP EPLDPGGENE AETAARQPLI GTETPESKPG ASWDLSLQER WTVFKGLLWY IIPLVLVYFA EYFINQGLFE LLFFRNTSLS HAQQYRWYQM LYQAGVFASR SSLQCCRIRF TWVLALLQCL NLALLLADVC LNFLPSIYLI FIIILYEGLL GGAAYVNTFH NIALETSDKH REFAMEAACI SDTLGISLSG VLALPLHDFL CHLP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.