Genular: Defining Cellular Identity and Function

Details for: Cxcr3

Gene ID: 12766

Symbol: Cxcr3

Ensembl ID: ENSMUSG00000050232

Description: C-X-C motif chemokine receptor 3

Associated with

Chemokine receptors bind chemokines
(R-MMU-380108)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (i) signalling events
(R-MMU-418594)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Angiogenesis
(GO:0001525)
C-c chemokine binding
(GO:0019957)
C-c chemokine receptor activity
(GO:0016493)
C-x-c chemokine binding
(GO:0019958)
C-x-c chemokine receptor activity
(GO:0016494)
Calcium-mediated signaling
(GO:0019722)
Cell chemotaxis
(GO:0060326)
Cell surface
(GO:0009986)
Cell surface receptor signaling pathway
(GO:0007166)
Chemokine binding
(GO:0019956)
Chemokine receptor activity
(GO:0004950)
Chemotaxis
(GO:0006935)
External side of plasma membrane
(GO:0009897)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Immune response
(GO:0006955)
Inflammatory response
(GO:0006954)
Membrane
(GO:0016020)
Negative regulation of angiogenesis
(GO:0016525)
Negative regulation of endothelial cell proliferation
(GO:0001937)
Negative regulation of execution phase of apoptosis
(GO:1900118)
Plasma membrane
(GO:0005886)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of chemotaxis
(GO:0050921)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of execution phase of apoptosis
(GO:1900119)
Positive regulation of release of sequestered calcium ion into cytosol
(GO:0051281)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Regulation of cell adhesion
(GO:0030155)
Regulation of leukocyte migration
(GO:0002685)
Signaling receptor activity
(GO:0038023)
Signal transduction
(GO:0007165)
T cell chemotaxis
(GO:0010818)

Other Information

Proteins

C-X-C chemokine receptor type 3

Genular Protein ID: 3121336192

Symbol: CXCR3_MOUSE

Name: C-X-C chemokine receptor type 3

UniProtKB Accession Codes:

O88410 Q4V9Y6 Q9QWN6

Database IDs:

Citations:

PubMed ID: 9653165

Title: The CC chemokine 6Ckine binds the CXC chemokine receptor CXCR3.

PubMed ID: 9653165

DOI: 10.1073/pnas.95.14.8205

PubMed ID: 9790904

Title: Cloning of the murine interferon-inducible protein 10 (IP-10) receptor and its specific expression in lymphoid organs.

PubMed ID: 9790904

DOI: 10.1006/bbrc.1998.9404

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 367
Mass: 41018
Checksum: EF0348A8358AD951
Sequence:

MYLEVSERQV LDASDFAFLL ENSTSPYDYG ENESDFSDSP PCPQDFSLNF DRTFLPALYS 
LLFLLGLLGN GAVAAVLLSQ RTALSSTDTF LLHLAVADVL LVLTLPLWAV DAAVQWVFGP 
GLCKVAGALF NINFYAGAFL LACISFDRYL SIVHATQIYR RDPRVRVALT CIVVWGLCLL 
FALPDFIYLS ANYDQRLNAT HCQYNFPQVG RTALRVLQLV AGFLLPLLVM AYCYAHILAV 
LLVSRGQRRF RAMRLVVVVV AAFAVCWTPY HLVVLVDILM DVGVLARNCG RESHVDVAKS 
VTSGMGYMHC CLNPLLYAFV GVKFREQMWM LFTRLGRSDQ RGPQRQPSSS RRESSWSETT 
EASYLGL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cxcr3

Associated with

Other Information

The CC chemokine 6Ckine binds the CXC chemokine receptor CXCR3. PubMed ID: 9653165

Cloning of the murine interferon-inducible protein 10 (IP-10) receptor and its specific expression in lymphoid organs. PubMed ID: 9790904

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Database document:

PubMed ID: 9653165

PubMed ID: 9790904

PubMed ID: 15489334

PubMed ID: 21183079