Genular: Defining Cellular Identity and Function

Details for: Ccr4

Gene ID: 12773

Symbol: Ccr4

Ensembl ID: ENSMUSG00000047898

Description: C-C motif chemokine receptor 4

Associated with

Chemokine receptors bind chemokines
(R-MMU-380108)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (i) signalling events
(R-MMU-418594)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
C-c chemokine binding
(GO:0019957)
C-c chemokine receptor activity
(GO:0016493)
Calcium-mediated signaling
(GO:0019722)
Cell chemotaxis
(GO:0060326)
Chemokine receptor activity
(GO:0004950)
Chemotaxis
(GO:0006935)
External side of plasma membrane
(GO:0009897)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Homeostasis of number of cells
(GO:0048872)
Immune response
(GO:0006955)
Inflammatory response
(GO:0006954)
Interneuron migration
(GO:1904936)
Membrane
(GO:0016020)
Neuronal cell body
(GO:0043025)
Neuron migration
(GO:0001764)
Plasma membrane
(GO:0005886)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of positive chemotaxis
(GO:0050927)
Signal transduction
(GO:0007165)
Tolerance induction
(GO:0002507)

Other Information

Proteins

C-C chemokine receptor type 4

Genular Protein ID: 1949172084

Symbol: CCR4_MOUSE

Name: C-C chemokine receptor type 4

UniProtKB Accession Codes:

P51680 Q14A03

Database IDs:

Citations:

PubMed ID: 8573157

Title: Molecular cloning of murine CC CKR-4 and high affinity binding of chemokines to murine and human CC CKR-4.

PubMed ID: 8573157

DOI: 10.1006/bbrc.1996.0059

PubMed ID: 9192769

Title: Molecular cloning and characterization of a cDNA, CHEMR1, encoding a chemokine receptor with a homology to the human C-C chemokine receptor, CCR-4.

PubMed ID: 9192769

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10811868

Title: A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock.

PubMed ID: 10811868

DOI: 10.1084/jem.191.10.1755

Sequence Information:

Length: 360
Mass: 41408
Checksum: 8FA760951BE2002B
Sequence:

MNATEVTDTT QDETVYNSYY FYESMPKPCT KEGIKAFGEV FLPPLYSLVF LLGLFGNSVV 
VLVLFKYKRL KSMTDVYLLN LAISDLLFVL SLPFWGYYAA DQWVFGLGLC KIVSWMYLVG 
FYSGIFFIML MSIDRYLAIV HAVFSLKART LTYGVITSLI TWSVAVFASL PGLLFSTCYT 
EHNHTYCKTQ YSVNSTTWKV LSSLEINVLG LLIPLGIMLF CYSMIIRTLQ HCKNEKKNRA 
VRMIFAVVVL FLGFWTPYNV VLFLETLVEL EVLQDCTLER YLDYAIQATE TLAFIHCCLN 
PVIYFFLGEK FRKYITQLFR TCRGPLVLCK HCDFLQVYSA DMSSSSYTQS TVDHDFRDAL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ccr4

Associated with

Other Information

Molecular cloning of murine CC CKR-4 and high affinity binding of chemokines to murine and human CC CKR-4. PubMed ID: 8573157

Molecular cloning and characterization of a cDNA, CHEMR1, encoding a chemokine receptor with a homology to the human C-C chemokine receptor, CCR-4. PubMed ID: 9192769

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock. PubMed ID: 10811868

Database document:

PubMed ID: 8573157

PubMed ID: 9192769

PubMed ID: 15489334

PubMed ID: 10811868