Genular: Defining Cellular Identity and Function

Details for: Ccr8

Gene ID: 12776

Symbol: Ccr8

Ensembl ID: ENSMUSG00000042262

Description: C-C motif chemokine receptor 8

Associated with

Chemokine receptors bind chemokines
(R-MMU-380108)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (i) signalling events
(R-MMU-418594)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
C-c chemokine binding
(GO:0019957)
C-c chemokine receptor activity
(GO:0016493)
Calcium-mediated signaling
(GO:0019722)
Cell chemotaxis
(GO:0060326)
Chemokine receptor activity
(GO:0004950)
Chemotaxis
(GO:0006935)
External side of plasma membrane
(GO:0009897)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Immune response
(GO:0006955)
Membrane
(GO:0016020)
Plasma membrane
(GO:0005886)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Protein binding
(GO:0005515)
Signal transduction
(GO:0007165)

Other Information

Proteins

C-C chemokine receptor type 8

Genular Protein ID: 446256742

Symbol: CCR8_MOUSE

Name: C-C chemokine receptor type 8

UniProtKB Accession Codes:

P56484

Database IDs:

Citations:

PubMed ID: 9469461

Title: Identification of CCR8 as the specific receptor for the human beta-chemokine I-309: cloning and molecular characterization of murine CCR8 as the receptor for TCA-3.

PubMed ID: 9469461

PubMed ID: 9670926

Title: The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells.

PubMed ID: 9670926

Sequence Information:

Length: 353
Mass: 40045
Checksum: 31EC4B642CDB9AE5
Sequence:

MDYTMEPNVT MTDYYPDFFT APCDAEFLLR GSMLYLAILY CVLFVLGLLG NSLVILVLVG 
CKKLRSITDI YLLNLAASDL LFVLSIPFQT HNLLDQWVFG TAMCKVVSGL YYIGFFSSMF 
FITLMSVDRY LAIVHAVYAI KVRTASVGTA LSLTVWLAAV TATIPLMVFY QVASEDGMLQ 
CFQFYEEQSL RWKLFTHFEI NALGLLLPFA ILLFCYVRIL QQLRGCLNHN RTRAIKLVLT 
VVIVSLLFWV PFNVALFLTS LHDLHILDGC ATRQRLALAI HVTEVISFTH CCVNPVIYAF 
IGEKFKKHLM DVFQKSCSHI FLYLGRQMPV GALERQLSSN QRSSHSSTLD DIL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.