Genular: Defining Cellular Identity and Function

Details for: Abcc2

Gene ID: 12780

Symbol: Abcc2

Ensembl ID: ENSMUSG00000025194

Description: ATP-binding cassette, sub-family member 2

Associated with

Abc-family proteins mediated transport
(R-MMU-382556)
Aspirin adme
(R-MMU-9749641)
Atorvastatin adme
(R-MMU-9754706)
Drug adme
(R-MMU-9748784)
Heme degradation
(R-MMU-189483)
Metabolism
(R-MMU-1430728)
Metabolism of porphyrins
(R-MMU-189445)
Paracetamol adme
(R-MMU-9753281)
Transport of small molecules
(R-MMU-382551)
Abc-type glutathione s-conjugate transporter activity
(GO:0015431)
Abc-type xenobiotic transporter activity
(GO:0008559)
Antibiotic metabolic process
(GO:0016999)
Apical plasma membrane
(GO:0016324)
Atpase-coupled transmembrane transporter activity
(GO:0042626)
Benzylpenicillin metabolic process
(GO:1901086)
Bile acid and bile salt transport
(GO:0015721)
Bilirubin transmembrane transporter activity
(GO:0015127)
Bilirubin transport
(GO:0015723)
Brush border membrane
(GO:0031526)
Canalicular bile acid transport
(GO:0015722)
Cell surface
(GO:0009986)
Detoxification of mercury ion
(GO:0050787)
Intercellular canaliculus
(GO:0046581)
Intracellular canaliculus
(GO:0046691)
Intracellular chloride ion homeostasis
(GO:0030644)
Leukotriene transport
(GO:0071716)
Membrane
(GO:0016020)
Mercury ion transport
(GO:0015694)
Negative regulation of gene expression
(GO:0010629)
Organic anion transport
(GO:0015711)
Plasma membrane
(GO:0005886)
Prostaglandin transport
(GO:0015732)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Response to estrogen
(GO:0043627)
Response to xenobiotic stimulus
(GO:0009410)
Thyroid hormone transport
(GO:0070327)
Transepithelial transport
(GO:0070633)
Transmembrane transport
(GO:0055085)
Xenobiotic catabolic process
(GO:0042178)
Xenobiotic detoxification by transmembrane export across the plasma membrane
(GO:1990961)
Xenobiotic export from cell
(GO:0046618)
Xenobiotic transmembrane transport
(GO:0006855)
Xenobiotic transmembrane transporter activity
(GO:0042910)
Xenobiotic transport across blood-brain barrier
(GO:1990962)

Other Information

Proteins

ATP-binding cassette sub-family C member 2

Genular Protein ID: 3654933962

Symbol: MRP2_MOUSE

Name: ATP-binding cassette sub-family C member 2

UniProtKB Accession Codes:

Q8VI47 Q8VI46

Database IDs:

Citations:

PubMed ID: 16421286

Title: Characterization of mice lacking the multidrug resistance protein MRP2 (ABCC2).

PubMed ID: 16421286

DOI: 10.1124/jpet.105.098665

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 1543
Mass: 173671
Checksum: 2D73F2881511FEC0
Sequence:

MDEFCNSTFW NLSLLKSPEA DLPLCFEQTV LVWIPLGFLW LLAPWQLYRI YRSRTKRFAI 
TKFYLAKQVF VVCLLILAAI DLSLALTEDT GQATIPPVKY TNPILYLCTW LLVLVIQHCR 
QCCIQKNSWF LSMFWILSLL CGIFQFQTLI RALLQDSKSN MTYSCLFFVS YGFQIVILIL 
SAFSESSDST HAPSATASFL SSVTFSWYDS TVLKGYKHPL TIEDVWDIEE NLKAKSLTSK 
FKTIMTKDLQ KARQALQRRL KKSQQSPEGT SHGLTKKQSQ SQDVLVLEDS KKKKKKSEAT 
KDFPKSWLVK ALFKTFYVVI LKSFILKLAH DILLFLNPQL LKFLIGFVKD PDSYPWVGYI 
YAILMFSVTL IQSFFLQCYF QFCFVLGMTV RTTIIASVYK KALTLSNLAR RQYTIGETVN 
LMSVDSQKLM DVTNYIHLLW SSVLQIALSI FFLWRELGPS ILAGVGLMVL LVPVNGVLAT 
KIRKIQVQNM KNKDKRLKIM NEILSGIKIL KYFAWEPSFK EQVNSIRKKE LRNLLRFSQL 
QTILIFILHL TPTLVSVITF SVYVLVDSQN VLNAEKAFTS ITLFNILRFP LAMLPMVISS 
VIQASVSVDR LEQYLGSDDL DLSAIRHVCH FDKAVQFSEA SFTWDRDLEA TIQDVNLDIK 
PGQLVAVVGT VGSGKSSLIS AMLGEMENVH GHITIKGSIA YVPQQAWIQN GTIKDNILFG 
SEYDEKKYQR VIEACALLPD LEMLPGGDMA EIGEKGINLS GGQKHRVSLA RATYQDADIY 
ILDDPLSAVD THVGKHIFNK VVGPNGLLSG KTRILVTHGI HFLPQVDEIV VLGKGTILEK 
GSYSDLMDKK GVFAKNWKTF MKHSGPEGEA TVDNDSEEED GDCGLIPTVE EIPDDAASLT 
MRRENSLRRT LSRSSRSGSR RGKSLKSSLK IKSVNALNKK EEVVKGQKLI KKEFVETGKV 
KFSIYLKYLQ AVGWWSLLFI VIFYVLNYVA FIGTNLWLSA WTSDSEKQNG TDNSPSQRDM 
RIGVFGALGI AQGIFLLSSS LWSIYACRNA SKTLHRQLLT NILRAPMSFF DTTPTGRIVN 
RFAGDISTVD DTLPQTLRSW LLCFFGIVST LVMICMATPI FIIIIIPLSI LYVSVQVFYV 
ATSRQLRRLD SVTKSPIYSH FSETVSGLPV IRAFEHQQRF LANSEKQIDT NQKCVFSWIT 
SNRWLAIRLE LVGNLIVFCS ALLLVIYKNS LTGDTVGFVL SNALNITQTL NWLVRMTSEV 
ETNIVAVERI NEYINVDNEA PWVTDKKPPA DWPKKGEIQF NNYQVRYRPE LDLVLKGITC 
NIKSTEKVGV VGRTGAGKSS LTNCLFRILE SAGGQIIIDG IDIASIGLHD LRGRLTIIPQ 
DPILFSGNLR MNLDPFNKYS DEEIWRALEL AHLKSFVAGL QLGLLHEVTE GGDNLSIGQR 
QLLCLGRAVL RKSKILVLDE ATAAVDLETD SLIQTTIRNE FSQCTVITIA HRLHTIMDSD 
KIMVLDSGKI VEYGSPEELL SNMGPFYLMA KEAGIESVNH TEL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.