Details for: COL4A1

Gene ID: 1282

Symbol: COL4A1

Ensembl ID: ENSG00000187498

Description: collagen type IV alpha 1 chain

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 6.1
    Marker Score: 4014
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 4.7
    Marker Score: 1718
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 4.3
    Marker Score: 37774.5
  • Cell Name: fat cell (CL0000136)
    Fold Change: 3.59
    Marker Score: 2003.5
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 3.34
    Marker Score: 4495
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 3.11
    Marker Score: 3316.5
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 3.09
    Marker Score: 3855
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 3.01
    Marker Score: 1633
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 2.99
    Marker Score: 5747
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 2.79
    Marker Score: 1549
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 2.77
    Marker Score: 1581
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.76
    Marker Score: 93922
  • Cell Name: smooth muscle cell of large intestine (CL1000279)
    Fold Change: 2.66
    Marker Score: 1007
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.64
    Marker Score: 3189
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.63
    Marker Score: 1541
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 2.49
    Marker Score: 1665
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 2.42
    Marker Score: 3517
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.4
    Marker Score: 2759
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.39
    Marker Score: 2283
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 2.33
    Marker Score: 2190
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 2.32
    Marker Score: 1311
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 2.29
    Marker Score: 5816
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 2.23
    Marker Score: 929
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 2.12
    Marker Score: 1341
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 2.1
    Marker Score: 9077
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.1
    Marker Score: 23625.5
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 2.09
    Marker Score: 542
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 2.07
    Marker Score: 69856
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 2.04
    Marker Score: 4804
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 1.99
    Marker Score: 2729
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 1.98
    Marker Score: 1689.5
  • Cell Name: endothelial cell of sinusoid (CL0002262)
    Fold Change: 1.97
    Marker Score: 477
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.95
    Marker Score: 8083
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.93
    Marker Score: 4235
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 1.86
    Marker Score: 3498
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.81
    Marker Score: 460
  • Cell Name: pericyte (CL0000669)
    Fold Change: 1.8
    Marker Score: 1051
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 1.79
    Marker Score: 2761.5
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 1.78
    Marker Score: 1170
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.77
    Marker Score: 554
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 1.76
    Marker Score: 2172
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 1.75
    Marker Score: 1160
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 1.73
    Marker Score: 673
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 1.69
    Marker Score: 1514.5
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 1.66
    Marker Score: 1790
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.65
    Marker Score: 521
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.64
    Marker Score: 596
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.59
    Marker Score: 1154.5
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: 1.58
    Marker Score: 2062
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 1.57
    Marker Score: 414
  • Cell Name: neural cell (CL0002319)
    Fold Change: 1.55
    Marker Score: 750
  • Cell Name: fibroblast of connective tissue of prostate (CL1000299)
    Fold Change: 1.53
    Marker Score: 380
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 1.52
    Marker Score: 356
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 1.52
    Marker Score: 3031.5
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.52
    Marker Score: 1012
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.52
    Marker Score: 1634
  • Cell Name: prostate stromal cell (CL0002622)
    Fold Change: 1.51
    Marker Score: 380
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.5
    Marker Score: 3528
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.49
    Marker Score: 9701
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.49
    Marker Score: 562
  • Cell Name: endothelial tip cell (CL0000704)
    Fold Change: 1.47
    Marker Score: 343
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.46
    Marker Score: 167188
  • Cell Name: muscle cell (CL0000187)
    Fold Change: 1.45
    Marker Score: 411
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.45
    Marker Score: 424
  • Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
    Fold Change: 1.44
    Marker Score: 324
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 1.4
    Marker Score: 2028.5
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.38
    Marker Score: 2810
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: 1.37
    Marker Score: 1233
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 1.36
    Marker Score: 17911.5
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.36
    Marker Score: 1452
  • Cell Name: type I pneumocyte (CL0002062)
    Fold Change: 1.35
    Marker Score: 1629
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.34
    Marker Score: 21000.5
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 1.34
    Marker Score: 3643
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.34
    Marker Score: 648.5
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.29
    Marker Score: 12941
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 1.28
    Marker Score: 317
  • Cell Name: glomerular endothelial cell (CL0002188)
    Fold Change: 1.26
    Marker Score: 320
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 1.25
    Marker Score: 1028
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 1.24
    Marker Score: 3258
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.23
    Marker Score: 18427
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 1.23
    Marker Score: 1189
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.23
    Marker Score: 945
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 1.21
    Marker Score: 292
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 1.2
    Marker Score: 1411
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.18
    Marker Score: 43669
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 1.17
    Marker Score: 832
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.17
    Marker Score: 3126
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 1.16
    Marker Score: 5711
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 1.16
    Marker Score: 723
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.15
    Marker Score: 1244
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.15
    Marker Score: 4815
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.14
    Marker Score: 1158
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.14
    Marker Score: 4049
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.14
    Marker Score: 4766
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 1.13
    Marker Score: 6695.5
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.13
    Marker Score: 259
  • Cell Name: peritubular capillary endothelial cell (CL1001033)
    Fold Change: 1.11
    Marker Score: 258
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 1.09
    Marker Score: 6545
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.08
    Marker Score: 24210
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 1.07
    Marker Score: 338

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Other Information

**Key characteristics:** * Col4a1 is a large protein (180 kDa) that is expressed in a variety of cell types. * It is a key component of the extracellular matrix, where it helps to form the structural framework for cells. * Mutations in the COL4A1 gene have been linked to a number of human diseases, including osteoporosis, rheumatoid arthritis, and asthma. **Pathways and functions:** * COL4A1 is involved in a variety of cellular processes, including cell migration, proliferation, and differentiation. * It is essential for the assembly of collagen fibrils, which are used to form the extracellular matrix. * Mutations in COL4A1 have been linked to a number of human diseases, including osteoporosis, rheumatoid arthritis, and asthma. **Clinical significance:** * COL4A1 is a promising target for the treatment of human diseases that are characterized by abnormal collagen metabolism. * Inhibitors of COL4A1 have been shown to be effective in preventing the development of osteoporosis and other collagen-related diseases. * Further research is needed to develop new treatments for these diseases.

Genular Protein ID: 4255595328

Symbol: CO4A1_HUMAN

Name: Arresten

UniProtKB Accession Codes:

P02462 A7E2W4 B1AM70 F5H5K0 Q1P9S9 Q5VWF6 Q86X41 Q8NF88 Q9NYC5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 57 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 20 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 MANE-Select 1 MIM 13 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 7 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 4 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 14 RefSeq 2 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2701944

Title: Structural organization of the gene for the alpha 1 chain of human type IV collagen.

PubMed ID: 2701944

DOI: 10.1016/s0021-9258(18)80034-5

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3311751

Title: Completion of the amino acid sequence of the alpha 1 chain of human basement membrane collagen (type IV) reveals 21 non-triplet interruptions located within the collagenous domain.

PubMed ID: 3311751

DOI: 10.1111/j.1432-1033.1987.tb13450.x

PubMed ID: 3182844

Title: The structural genes for alpha 1 and alpha 2 chains of human type IV collagen are divergently encoded on opposite DNA strands and have an overlapping promoter region.

PubMed ID: 3182844

DOI: 10.1016/s0021-9258(19)77818-1

PubMed ID: 4043082

Title: Amino acid sequence of the N-terminal aggregation and cross-linking region (7S domain) of the alpha 1 (IV) chain of human basement membrane collagen.

PubMed ID: 4043082

DOI: 10.1111/j.1432-1033.1985.tb09186.x

PubMed ID: 3691802

Title: Complete primary structure of the alpha 1-chain of human basement membrane (type IV) collagen.

PubMed ID: 3691802

DOI: 10.1016/0014-5793(87)81155-9

PubMed ID: 6434307

Title: Structure of human-basement-membrane (type IV) collagen. Complete amino-acid sequence of a 914-residue-long pepsin fragment from the alpha 1(IV) chain.

PubMed ID: 6434307

DOI: 10.1111/j.1432-1033.1984.tb08404.x

PubMed ID: 2581969

Title: cDNA clones coding for the pro-alpha1(IV) chain of human type IV procollagen reveal an unusual homology of amino acid sequences in two halves of the carboxyl-terminal domain.

PubMed ID: 2581969

DOI: 10.1016/s0021-9258(17)39662-x

PubMed ID: 2582422

Title: Restricted homology between human alpha 1 type IV and other procollagen chains.

PubMed ID: 2582422

DOI: 10.1073/pnas.82.11.3649

PubMed ID: 2844531

Title: The arrangement of intra- and intermolecular disulfide bonds in the carboxyterminal, non-collagenous aggregation and cross-linking domain of basement-membrane type IV collagen.

PubMed ID: 2844531

DOI: 10.1111/j.1432-1033.1988.tb14321.x

PubMed ID: 10811134

Title: Anti-angiogenic cues from vascular basement membrane collagen.

PubMed ID: 10811134

PubMed ID: 16481288

Title: Construction of recombinant plasmid and prokaryotic expression in E. coli and biological activity analysis of human placenta arresten gene.

PubMed ID: 16481288

PubMed ID: 16151532

Title: Human alpha1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by alpha1beta1 integrin.

PubMed ID: 16151532

DOI: 10.1172/jci24813

PubMed ID: 31895054

Title:

PubMed ID: 31895054

DOI: 10.1172/jci135305

PubMed ID: 18775695

Title: Characterization of the anti-angiogenic properties of arresten, an alpha1beta1 integrin-dependent collagen-derived tumor suppressor.

PubMed ID: 18775695

DOI: 10.1016/j.yexcr.2008.08.011

PubMed ID: 22522439

Title: COL4A1 mutations in patients with sporadic late-onset intracerebral hemorrhage.

PubMed ID: 22522439

DOI: 10.1002/ana.22682

PubMed ID: 22574627

Title: Childhood presentation of COL4A1 mutations.

PubMed ID: 22574627

DOI: 10.1111/j.1469-8749.2011.04198.x

PubMed ID: 23394911

Title: Variants of anterior segment dysgenesis and cerebral involvement in a large family with a novel COL4A1 mutation.

PubMed ID: 23394911

DOI: 10.1016/j.ajo.2012.11.028

PubMed ID: 23225343

Title: Phenotypic spectrum of COL4A1 mutations: porencephaly to schizencephaly.

PubMed ID: 23225343

DOI: 10.1002/ana.23736

PubMed ID: 25228067

Title: Next generation sequencing uncovers a missense mutation in COL4A1 as the cause of familial retinal arteriolar tortuosity.

PubMed ID: 25228067

DOI: 10.1007/s00417-014-2800-6

PubMed ID: 24628545

Title: Whole exome analysis identifies dominant COL4A1 mutations in patients with complex ocular phenotypes involving microphthalmia.

PubMed ID: 24628545

DOI: 10.1111/cge.12379

PubMed ID: 27666438

Title: Disruption of a miR-29 binding site leading to COL4A1 upregulation causes pontine autosomal dominant microangiopathy with leukoencephalopathy.

PubMed ID: 27666438

DOI: 10.1002/ana.24782

PubMed ID: 28369186

Title: Multi-infarct dementia of Swedish type is caused by a 3'UTR mutation of COL4A1.

PubMed ID: 28369186

DOI: 10.1093/brain/awx062

PubMed ID: 12011424

Title: The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link.

PubMed ID: 12011424

DOI: 10.1073/pnas.062183499

PubMed ID: 15905400

Title: Mutations in Col4a1 cause perinatal cerebral hemorrhage and porencephaly.

PubMed ID: 15905400

DOI: 10.1126/science.1109418

PubMed ID: 16107487

Title: Novel mutations in three families confirm a major role of COL4A1 in hereditary porencephaly.

PubMed ID: 16107487

DOI: 10.1136/jmg.2005.035584

PubMed ID: 16598045

Title: Role of COL4A1 in small-vessel disease and hemorrhagic stroke.

PubMed ID: 16598045

DOI: 10.1056/nejmoa053727

PubMed ID: 17696175

Title: COL4A1 mutation in Axenfeld-Rieger anomaly with leukoencephalopathy and stroke.

PubMed ID: 17696175

DOI: 10.1002/ana.21191

PubMed ID: 18160688

Title: COL4A1 mutations and hereditary angiopathy, nephropathy, aneurysms, and muscle cramps.

PubMed ID: 18160688

DOI: 10.1056/nejmoa071906

PubMed ID: 17379824

Title: COL4A1 mutation in a patient with sporadic, recurrent intracerebral hemorrhage.

PubMed ID: 17379824

DOI: 10.1161/strokeaha.106.475194

PubMed ID: 19194877

Title: COL4A1 mutation in two preterm siblings with antenatal onset of parenchymal hemorrhage.

PubMed ID: 19194877

DOI: 10.1002/ana.21525

PubMed ID: 20818663

Title: Novel COL4A1 mutations associated with HANAC syndrome: a role for the triple helical CB3[IV] domain.

PubMed ID: 20818663

DOI: 10.1002/ajmg.a.33659

PubMed ID: 20385946

Title: Ophthalmological features associated with COL4A1 mutations.

PubMed ID: 20385946

DOI: 10.1001/archophthalmol.2010.42

PubMed ID: 19477666

Title: A dominantly inherited mutation in collagen IV A1 (COL4A1) causing childhood onset stroke without porencephaly.

PubMed ID: 19477666

DOI: 10.1016/j.ejpn.2009.04.010

PubMed ID: 21527998

Title: Sequence variants in COL4A1 and COL4A2 genes in Ecuadorian families with keratoconus.

PubMed ID: 21527998

Sequence Information:

  • Length: 1669
  • Mass: 160611
  • Checksum: 3BEBA6DFFB9B8A84
  • Sequence:
    • MGPRLSVWLL LLPAALLLHE EHSRAAAKGG CAGSGCGKCD CHGVKGQKGE RGLPGLQGVI 
GFPGMQGPEG PQGPPGQKGD TGEPGLPGTK GTRGPPGASG YPGNPGLPGI PGQDGPPGPP 
GIPGCNGTKG ERGPLGPPGL PGFAGNPGPP GLPGMKGDPG EILGHVPGML LKGERGFPGI 
PGTPGPPGLP GLQGPVGPPG FTGPPGPPGP PGPPGEKGQM GLSFQGPKGD KGDQGVSGPP 
GVPGQAQVQE KGDFATKGEK GQKGEPGFQG MPGVGEKGEP GKPGPRGKPG KDGDKGEKGS 
PGFPGEPGYP GLIGRQGPQG EKGEAGPPGP PGIVIGTGPL GEKGERGYPG TPGPRGEPGP 
KGFPGLPGQP GPPGLPVPGQ AGAPGFPGER GEKGDRGFPG TSLPGPSGRD GLPGPPGSPG 
PPGQPGYTNG IVECQPGPPG DQGPPGIPGQ PGFIGEIGEK GQKGESCLIC DIDGYRGPPG 
PQGPPGEIGF PGQPGAKGDR GLPGRDGVAG VPGPQGTPGL IGQPGAKGEP GEFYFDLRLK 
GDKGDPGFPG QPGMPGRAGS PGRDGHPGLP GPKGSPGSVG LKGERGPPGG VGFPGSRGDT 
GPPGPPGYGP AGPIGDKGQA GFPGGPGSPG LPGPKGEPGK IVPLPGPPGA EGLPGSPGFP 
GPQGDRGFPG TPGRPGLPGE KGAVGQPGIG FPGPPGPKGV DGLPGDMGPP GTPGRPGFNG 
LPGNPGVQGQ KGEPGVGLPG LKGLPGLPGI PGTPGEKGSI GVPGVPGEHG AIGPPGLQGI 
RGEPGPPGLP GSVGSPGVPG IGPPGARGPP GGQGPPGLSG PPGIKGEKGF PGFPGLDMPG 
PKGDKGAQGL PGITGQSGLP GLPGQQGAPG IPGFPGSKGE MGVMGTPGQP GSPGPVGAPG 
LPGEKGDHGF PGSSGPRGDP GLKGDKGDVG LPGKPGSMDK VDMGSMKGQK GDQGEKGQIG 
PIGEKGSRGD PGTPGVPGKD GQAGQPGQPG PKGDPGISGT PGAPGLPGPK GSVGGMGLPG 
TPGEKGVPGI PGPQGSPGLP GDKGAKGEKG QAGPPGIGIP GLRGEKGDQG IAGFPGSPGE 
KGEKGSIGIP GMPGSPGLKG SPGSVGYPGS PGLPGEKGDK GLPGLDGIPG VKGEAGLPGT 
PGPTGPAGQK GEPGSDGIPG SAGEKGEPGL PGRGFPGFPG AKGDKGSKGE VGFPGLAGSP 
GIPGSKGEQG FMGPPGPQGQ PGLPGSPGHA TEGPKGDRGP QGQPGLPGLP GPMGPPGLPG 
IDGVKGDKGN PGWPGAPGVP GPKGDPGFQG MPGIGGSPGI TGSKGDMGPP GVPGFQGPKG 
LPGLQGIKGD QGDQGVPGAK GLPGPPGPPG PYDIIKGEPG LPGPEGPPGL KGLQGLPGPK 
GQQGVTGLVG IPGPPGIPGF DGAPGQKGEM GPAGPTGPRG FPGPPGPDGL PGSMGPPGTP 
SVDHGFLVTR HSQTIDDPQC PSGTKILYHG YSLLYVQGNE RAHGQDLGTA GSCLRKFSTM 
PFLFCNINNV CNFASRNDYS YWLSTPEPMP MSMAPITGEN IRPFISRCAV CEAPAMVMAV 
HSQTIQIPPC PSGWSSLWIG YSFVMHTSAG AEGSGQALAS PGSCLEEFRS APFIECHGRG 
TCNYYANAYS FWLATIERSE MFKKPTPSTL KAGELRTHVS RCQVCMRRT

Genular Protein ID: 1642549698

Symbol: A5PKV2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A5PKV2

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 ChiTaRS 1 DNASU 1 EMBL 2 GenomeRNAi 1 InterPro 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 519
  • Mass: 50184
  • Checksum: FD8319AAFDBF46B2
  • Sequence:
    • MGPRLSLWLL LLPAALLLHE EHSRAAAKGG CAGSGCGKCD CHGVKGQKGE RGLPGLQGVI 
GFPGMQGPEG PQGPPGQKGD TGEPGLPGTK GTRGPPGASG YPGNPGLPGI PGQDGPPGPP 
GIPGCNGTKG ERGPLGPPGL PGFAGNPGPP GLPGMKGDPG EILGHVPGML LKGERGFPGI 
PGTPGPPGLP GLQGPVGPPG FTGPPGPPGP PGPPGEKGQM GLSFQGPKGD KGDQGVSGPP 
GVPGQAQVQE KGDFATKGEK GQKAEPGFQG MPGVGEKGEP GKPGPRGKPG KDGDKGEKGS 
PGFPGEPGYP GLIGRQGPQG EKGEAGPPGP PGIVIGTGPL GEKGERGYPG TPGPRGEPGP 
KGFPGLPGQP GPPGLPVPGQ AGAPGFPGER GEKGDRGFPG TSLPGPSGRD GLPGPPGSPG 
PPGQPGYTNG IVECQPGPPG DQGPPGIPGQ PGFIGEIGEK GQKGESCLIC DIDGYRGPPG 
PQGPPGEIGF PGQPGAKGDR GLPGRDGVAG VPLLFQIHK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.