Col2a1 | ENSMUSG00000022483 | NCBI 12824

Details for: Col2a1

Gene ID: 12824

Symbol: Col2a1

Ensembl ID: ENSMUSG00000022483

Description: collagen, type II, alpha 1

Associated with

Adaptive immune system
(R-MMU-1280218)
Assembly of collagen fibrils and other multimeric structures
(R-MMU-2022090)
Axon guidance
(R-MMU-422475)
Collagen biosynthesis and modifying enzymes
(R-MMU-1650814)
Collagen chain trimerization
(R-MMU-8948216)
Collagen degradation
(R-MMU-1442490)
Collagen formation
(R-MMU-1474290)
Degradation of the extracellular matrix
(R-MMU-1474228)
Developmental biology
(R-MMU-1266738)
Ecm proteoglycans
(R-MMU-3000178)
Extracellular matrix organization
(R-MMU-1474244)
Immune system
(R-MMU-168256)
Immunoregulatory interactions between a lymphoid and a non-lymphoid cell
(R-MMU-198933)
Integrin cell surface interactions
(R-MMU-216083)
Met activates ptk2 signaling
(R-MMU-8874081)
Met promotes cell motility
(R-MMU-8875878)
Ncam1 interactions
(R-MMU-419037)
Ncam signaling for neurite out-growth
(R-MMU-375165)
Nervous system development
(R-MMU-9675108)
Non-integrin membrane-ecm interactions
(R-MMU-3000171)
Signaling by met
(R-MMU-6806834)
Signaling by pdgf
(R-MMU-186797)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signal transduction
(R-MMU-162582)
Anterior head development
(GO:0097065)
Basement membrane
(GO:0005604)
Bone development
(GO:0060348)
Cartilage condensation
(GO:0001502)
Cartilage development
(GO:0051216)
Cartilage development involved in endochondral bone morphogenesis
(GO:0060351)
Cellular response to bmp stimulus
(GO:0071773)
Central nervous system development
(GO:0007417)
Chondrocyte differentiation
(GO:0002062)
Collagen-containing extracellular matrix
(GO:0062023)
Collagen fibril organization
(GO:0030199)
Collagen trimer
(GO:0005581)
Collagen type ii trimer
(GO:0005585)
Collagen type xi trimer
(GO:0005592)
Cytoplasm
(GO:0005737)
Embryonic skeletal joint morphogenesis
(GO:0060272)
Endochondral ossification
(GO:0001958)
Extracellular matrix
(GO:0031012)
Extracellular matrix structural constituent
(GO:0005201)
Extracellular matrix structural constituent conferring tensile strength
(GO:0030020)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Extrinsic apoptotic signaling pathway in absence of ligand
(GO:0097192)
Heart morphogenesis
(GO:0003007)
Identical protein binding
(GO:0042802)
Inner ear development
(GO:0048839)
Inner ear morphogenesis
(GO:0042472)
Limb bud formation
(GO:0060174)
Limb morphogenesis
(GO:0035108)
Metal ion binding
(GO:0046872)
Mhc class ii protein binding
(GO:0042289)
Negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
(GO:2001240)
Notochord development
(GO:0030903)
Ossification
(GO:0001503)
Otic vesicle development
(GO:0071599)
Platelet-derived growth factor binding
(GO:0048407)
Protein homodimerization activity
(GO:0042803)
Proteoglycan binding
(GO:0043394)
Proteoglycan metabolic process
(GO:0006029)
Regulation of gene expression
(GO:0010468)
Roof of mouth development
(GO:0060021)
Sensory perception of sound
(GO:0007605)
Skeletal system development
(GO:0001501)
Skeletal system morphogenesis
(GO:0048705)
Tissue homeostasis
(GO:0001894)
Visual perception
(GO:0007601)

Other Information

Proteins

CO2A1_MOUSE

Genular Protein ID: 99923732

Symbol: CO2A1_MOUSE

Name: N/A

UniProtKB Accession Codes:

P28481 Q61428 Q62031 Q62032 Q62033 Q641K3 Q6LDB1 Q6LDI8 Q6LDI9 Q80VY3 Q80X38 Q8CEF7 Q8K0N6

Database IDs:

Citations:

PubMed ID: 1885613

Title: Mouse type II collagen gene. Complete nucleotide sequence, exon structure, and alternative splicing.

PubMed ID: 1885613

DOI: 10.1016/s0021-9258(18)55382-5

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1879363

Title: Expression of the mouse alpha 1(II) collagen gene is not restricted to cartilage during development.

PubMed ID: 1879363

DOI: 10.1242/dev.111.4.945

PubMed ID: 1797232

Title: The mouse Col2a-1 gene is highly conserved and is linked to Int-1 on chromosome 15.

PubMed ID: 1797232

DOI: 10.1007/bf00351064

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 2054384

Title: Specific hybridization probes for mouse type I, II, III and IX collagen mRNAs.

PubMed ID: 2054384

DOI: 10.1016/0167-4781(91)90014-d

PubMed ID: 12968670

Title: A missense mutation in the mouse Col2a1 gene causes spondyloepiphyseal dysplasia congenita, hearing loss, and retinoschisis.

PubMed ID: 12968670

DOI: 10.1359/jbmr.2003.18.9.1612

Sequence Information:

Length: 1487
Mass: 141973
Checksum: E52A7F3951C76701
Sequence:

MIRLGAPQSL VLLTLLIAAV LRCQGQDAQE AGSCLQNGQR YKDKDVWKPS SCRICVCDTG 
NVLCDDIICE DPDCLNPEIP FGECCPICPA DLATASGKLG PKGQKGEPGD IRDIIGPRGP 
PGPQGPAGEQ GPRGDRGDKG EKGAPGPRGR DGEPGTPGNP GPAGPPGPPG PPGLSAGNFA 
AQMAGGYDEK AGGAQMGVMQ GPMGPMGPRG PPGPAGAPGP QGFQGNPGEP GEPGVSGPMG 
PRGPPGPAGK PGDDGEAGKP GKSGERGLPG PQGARGFPGT PGLPGVKGHR GYPGLDGAKG 
EAGAPGVKGE SGSPGENGSP GPMGPRGLPG ERGRTGPAGA AGARGNDGQP GPAGPPGPVG 
PAGGPGFPGA PGAKGEAGPT GARGPEGAQG SRGEPGNPGS PGPAGASGNP GTDGIPGAKG 
SAGAPGIAGA PGFPGPRGPP GPQGATGPLG PKGQAGEPGI AGFKGDQGPK GETGPAGPQG 
APGPAGEEGK RGARGEPGGA GPIGPPGERG APGNRGFPGQ DGLAGPKGAP GERGPSGLTG 
PKGANGDPGR PGEPGLPGAR GLTGRPGDAG PQGKVGPSGA PGEDGRPGPP GPQGARGQPG 
VMGFPGPKGA NGEPGKAGEK GLAGAPGLRG LPGKDGETGA AGPPGPSGPA GERGEQGAPG 
PSGFQGLPGP PGPPGEGGKQ GDQGIPGEAG APGLVGPRGE RGFPGERGSP GAQGLQGPRG 
LPGTPGTDGP KGAAGPDGPP GAQGPPGLQG MPGERGAAGI AGPKGDRGDV GEKGPEGAPG 
KDGGRGLTGP IGPPGPAGAN GEKGEVGPPG PSGSTGARGA PGERGETGPP GPAGFAGPPG 
ADGQPGAKGD QGEAGQKGDA GAPGPQGPSG APGPQGPTGV TGPKGARGAQ GPPGATGFPG 
AAGRVGPPGA NGNPGPAGPP GPAGKDGPKG VRGDSGPPGR AGDPGLQGPA GAPGEKGEPG 
DDGPSGLDGP PGPQGLAGQR GIVGLPGQRG ERGFPGLPGP SGEPGKQGAP GASGDRGPPG 
PVGPPGLTGP AGEPGREGSP GADGPPGRDG AAGVKGDRGE TGALGAPGAP GPPGSPGPAG 
PTGKQGDRGE AGAQGPMGPS GPAGARGIAG PQGPRGDKGE SGEQGERGLK GHRGFTGLQG 
LPGPPGPSGD QGASGPAGPS GPRGPPGPVG PSGKDGSNGI PGPIGPPGPR GRSGETGPVG 
PPGSPGPPGP PGPPGPGIDM SAFAGLGQRE KGPDPMQYMR ADEADSTLRQ HDVEVDATLK 
SLNNQIESIR SPDGSRKNPA RTCQDLKLCH PEWKSGDYWI DPNQGCTLDA MKVFCNMETG 
ETCVYPNPAT VPRKNWWSSK SKEKKHIWFG ETMNGGFHFS YGDGNLAPNT ANVQMTFLRL 
LSTEGSQNIT YHCKNSIAYL DEAAGNLKKA LLIQGSNDVE MRAEGNSRFT YTALKDGCTK 
HTGKWGKTVI EYRSQKTSRL PIIDIAPMDI GGAEQEFGVD IGPVCFL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Col2a1

Associated with

Other Information

Mouse type II collagen gene. Complete nucleotide sequence, exon structure, and alternative splicing. PubMed ID: 1885613

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Expression of the mouse alpha 1(II) collagen gene is not restricted to cartilage during development. PubMed ID: 1879363

The mouse Col2a-1 gene is highly conserved and is linked to Int-1 on chromosome 15. PubMed ID: 1797232

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Specific hybridization probes for mouse type I, II, III and IX collagen mRNAs. PubMed ID: 2054384

A missense mutation in the mouse Col2a1 gene causes spondyloepiphyseal dysplasia congenita, hearing loss, and retinoschisis. PubMed ID: 12968670