Genular: Defining Cellular Identity and Function

Details for: Col5a1

Gene ID: 12831

Symbol: Col5a1

Ensembl ID: ENSMUSG00000026837

Description: collagen, type V, alpha 1

Associated with

Assembly of collagen fibrils and other multimeric structures
(R-MMU-2022090)
Axon guidance
(R-MMU-422475)
Collagen biosynthesis and modifying enzymes
(R-MMU-1650814)
Collagen chain trimerization
(R-MMU-8948216)
Collagen degradation
(R-MMU-1442490)
Collagen formation
(R-MMU-1474290)
Degradation of the extracellular matrix
(R-MMU-1474228)
Developmental biology
(R-MMU-1266738)
Ecm proteoglycans
(R-MMU-3000178)
Extracellular matrix organization
(R-MMU-1474244)
Integrin cell surface interactions
(R-MMU-216083)
Met activates ptk2 signaling
(R-MMU-8874081)
Met promotes cell motility
(R-MMU-8875878)
Ncam1 interactions
(R-MMU-419037)
Ncam signaling for neurite out-growth
(R-MMU-375165)
Nervous system development
(R-MMU-9675108)
Non-integrin membrane-ecm interactions
(R-MMU-3000171)
Signaling by met
(R-MMU-6806834)
Signaling by pdgf
(R-MMU-186797)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signal transduction
(R-MMU-162582)
Basement membrane
(GO:0005604)
Blood vessel development
(GO:0001568)
Cell adhesion
(GO:0007155)
Cell migration
(GO:0016477)
Collagen-containing extracellular matrix
(GO:0062023)
Collagen biosynthetic process
(GO:0032964)
Collagen fibril organization
(GO:0030199)
Collagen trimer
(GO:0005581)
Collagen type v trimer
(GO:0005588)
Collagen type xi trimer
(GO:0005592)
Extracellular matrix
(GO:0031012)
Extracellular matrix structural constituent
(GO:0005201)
Extracellular matrix structural constituent conferring tensile strength
(GO:0030020)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Eye morphogenesis
(GO:0048592)
Heart morphogenesis
(GO:0003007)
Heparin binding
(GO:0008201)
Integrin biosynthetic process
(GO:0045112)
Negative regulation of endodermal cell differentiation
(GO:1903225)
Platelet-derived growth factor binding
(GO:0048407)
Protein binding
(GO:0005515)
Proteoglycan binding
(GO:0043394)
Regulation of cellular component organization
(GO:0051128)
Skin development
(GO:0043588)
Supramolecular fiber organization
(GO:0097435)
Tendon development
(GO:0035989)
Wound healing, spreading of epidermal cells
(GO:0035313)

Other Information

Proteins

Collagen alpha-1(V) chain

Genular Protein ID: 1135335372

Symbol: CO5A1_MOUSE

Name: Collagen alpha-1(V) chain

UniProtKB Accession Codes:

O88207 A3KGE3 Q3UG94 Q6F6B0

Database IDs:

Citations:

PubMed ID: 9582436

Title: cDNA sequence and expression of the mouse alpha1(V) collagen gene.

PubMed ID: 9582436

DOI: 10.1016/s0167-4781(98)00016-5

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15246108

Title: Identification of a functional CBF-binding CCAAT-like motif in the core promoter of the mouse pro-alpha1(V) collagen gene (Col5a1).

PubMed ID: 15246108

DOI: 10.1016/j.matbio.2004.03.003

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22149965

Title: Characterization of tissue-specific and developmentally regulated alternative splicing of exon 64 in the COL5A1 gene.

PubMed ID: 22149965

DOI: 10.3109/03008207.2011.636160

Sequence Information:

Length: 1838
Mass: 183677
Checksum: D20F4E5198A09ECF
Sequence:

MDVHTRWKAA RPGALLLSSP LLLFLLLLWA PPSSRAAQPA DLLEMLDFHN LPSGVTKTTG 
FCATRRSSSE PDVAYRVSKD AQLSMPTKQL YPESGFPEDF SILTTVKAKK GSQAFLVSIY 
NEQGIQQLGL ELGRSPVFLY EDHTGKPGPE EYPLFPGINL SDGKWHRIAL SVYKKNVTLI 
LDCKKKITKF LSRSDHPIID TNGIVMFGSR ILDDEIFEGD IQQLLFVSDN RAAYDYCEHY 
SPDCDTAVPD TPQSQDPNPD EYYPEGEGET YYYEYPYYED PEDPGKEPAP TQKPVEAARE 
TTEVPEEQTQ PLPEAPTVPE TSDTADKEDS LGIGDYDYVP PDDYYTPPPY EDFGYGEGVE 
NPDQPTNPDS GAEVPTSTTV TSNTSNPAPG EGKDDLGGEF TEETIKNLEE NYYDPYFDPD 
SDSSVSPSEI GPGMPANQDT IFEGIGGPRG EKGQKGEPAI IEPGMLIEGP PGPEGPAGLP 
GPPGTTGPTG QMGDPGERGP PGRPGLPGAD GLPGPPGTML MLPFRFGGGG DAGSKGPMVS 
AQESQAQAIL QQARLALRGP AGPMGLTGRP GPMGPPGSGG LKGEPGDMGP QGPRGVQGPP 
GPTGKPGRRG RAGSDGARGM PGQTGPKGDR GFDGLAGLPG EKGHRGDPGP SGPPGIPGDD 
GERGDDGEVG PRGLPGEPGP RGLLGPKGPP GPPGPPGVTG MDGQPGPKGN VGPQGEPGPP 
GQQGNPGAQG LPGPQGAIGP PGEKGPLGKP GLPGMPGADG PPGHPGKEGP PGEKGGQGPP 
GPQGPIGYPG PRGVKGADGI RGLKGTKGEK GEDGFPGFKG DMGIKGDRGE IGPPGPRGED 
GPEGPKGRGG PNGDPGPLGP TGEKGKLGVP GLPGYPGRQG PKGSIGFPGF PGANGEKGGR 
GTPGKPGPRG QRGPTGPRGE RGPRGITGKP GPKGNSGGDG PAGPPGERGP NGPQGPTGFP 
GPKGPPGPPG KDGLPGHPGQ RGETGFQGKT GPPGPPGVVG PQGPTGETGP MGERGHPGPP 
GPPGEQGLPG AAGKEGTKGD PGPAGLPGKD GPPGLRGFPG DRGLPGPVGA LGLKGSEGPP 
GPPGPAGSPG ERGPAGAAGP IGIPGRPGPQ GPPGPAGEKG LPGEKGPQGP AGRDGLQGPV 
GLPGPAGPVG PPGEDGDKGE IGEPGQKGSK GDKGEQGPPG PTGPQGPIGQ PGPSGADGEP 
GPRGQQGLFG QKGDEGSRGF PGPPGPVGLQ GLPGPPGEKG ETGDVGQMGP PGPPGPRGPS 
GAPGADGPQG PPGGIGNPGA VGEKGEPGEA GDPGLPGEGG PLGPKGERGE KGEAGPSGAA 
GPPGPKGPPG DDGPKGSPGP VGFPGDPGPP GEPGPAGQDG PPGDKGDDGE PGQTGSPGPT 
GEPGPSGPPG KRGPPGPAGP EGRQGEKGAK GEAGLEGPPG KTGPIGPQGA PGKPGPDGLR 
GIPGPVGEQG LPGSPGPDGP PGPMGPPGLP GLKGDSGPKG EKGHPGLIGL IGPPGEQGEK 
GDRGLPGPQG SSGPKGDQGI TGPSGPLGPP GPPGLPGPPG PKGAKGSSGP TGPKGEAGHP 
GLPGPPGPPG EVIQPLPIQA SRTRRNIDAS QLLDDGAGES YVDYADGMEE IFGSLNSLKL 
EIEQMKRPLG TQQNPARTCK DLQLCHPDFP DGEYWVDPNQ GCSRDSFKVY CNFTAGGSTC 
VFPDKKSEGA RITSWPKENP GSWFSEFKRG KLLSYVDAEG NPVGVVQMTF LRLLSASAHQ 
NVTYNCYQSV AWQDAATGSY DKAIRFLGSN DEEMSYDNNP YIRALVDGCA TKKGYQKTVL 
EIDTPKVEQV PIVDIMFNDF GEASQKFGFE VGPACFLG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Col5a1

Associated with

Other Information

cDNA sequence and expression of the mouse alpha1(V) collagen gene. PubMed ID: 9582436

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Identification of a functional CBF-binding CCAAT-like motif in the core promoter of the mouse pro-alpha1(V) collagen gene (Col5a1). PubMed ID: 15246108

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079