Genular: Defining Cellular Identity and Function

Details for: Col5a2

Gene ID: 12832

Symbol: Col5a2

Ensembl ID: ENSMUSG00000026042

Description: collagen, type V, alpha 2

Associated with

Assembly of collagen fibrils and other multimeric structures
(R-MMU-2022090)
Axon guidance
(R-MMU-422475)
Collagen biosynthesis and modifying enzymes
(R-MMU-1650814)
Collagen chain trimerization
(R-MMU-8948216)
Collagen degradation
(R-MMU-1442490)
Collagen formation
(R-MMU-1474290)
Degradation of the extracellular matrix
(R-MMU-1474228)
Developmental biology
(R-MMU-1266738)
Ecm proteoglycans
(R-MMU-3000178)
Integrin cell surface interactions
(R-MMU-216083)
Met activates ptk2 signaling
(R-MMU-8874081)
Met promotes cell motility
(R-MMU-8875878)
Ncam1 interactions
(R-MMU-419037)
Ncam signaling for neurite out-growth
(R-MMU-375165)
Nervous system development
(R-MMU-9675108)
Non-integrin membrane-ecm interactions
(R-MMU-3000171)
Signaling by met
(R-MMU-6806834)
Signaling by pdgf
(R-MMU-186797)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signal transduction
(R-MMU-162582)
Cellular response to amino acid stimulus
(GO:0071230)
Collagen-containing extracellular matrix
(GO:0062023)
Collagen fibril organization
(GO:0030199)
Collagen trimer
(GO:0005581)
Collagen type v trimer
(GO:0005588)
Collagen type xi trimer
(GO:0005592)
Extracellular matrix organization
(GO:0030198)
Extracellular matrix structural constituent
(GO:0005201)
Extracellular matrix structural constituent conferring tensile strength
(GO:0030020)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Eye morphogenesis
(GO:0048592)
Metal ion binding
(GO:0046872)
Negative regulation of endodermal cell differentiation
(GO:1903225)
Skeletal system development
(GO:0001501)
Skin development
(GO:0043588)
Smad binding
(GO:0046332)

Other Information

Proteins

Collagen alpha-2(V) chain

Genular Protein ID: 3203125579

Symbol: CO5A2_MOUSE

Name: Collagen alpha-2(V) chain

UniProtKB Accession Codes:

Q3U962 Q3TVR2 Q3UHK7 Q3UTT4 Q3V1J6 Q61431 Q7TMS0 Q80VS8

Database IDs:

Citations:

PubMed ID: 1297453

Title: Localization of pro-alpha 2(V) collagen transcripts in the tissues of the developing mouse embryo.

PubMed ID: 1297453

DOI: 10.1002/aja.1001950205

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7704020

Title: Targeted mutation in the col5a2 gene reveals a regulatory role for type V collagen during matrix assembly.

PubMed ID: 7704020

DOI: 10.1038/ng0195-31

PubMed ID: 9642685

Title: Effect of targeted mutation in collagen V alpha 2 gene on development of cutaneous hyperplasia in tight skin mice.

PubMed ID: 9642685

DOI: 10.1007/bf03401742

PubMed ID: 15199158

Title: Development of a functional skin matrix requires deposition of collagen V heterotrimers.

PubMed ID: 15199158

DOI: 10.1128/mcb.24.13.6049-6057.2004

Sequence Information:

Length: 1497
Mass: 145018
Checksum: CAAE15514984DB41
Sequence:

MMANWVGARP LLILSVLLGY CVSIKAQEQE NDEYDEEIAC TQHGQMYLNR DIWKPSPCQI 
CVCDNGAILC DKIECPEVLN CANPITPTGE CCPVCPQTGG GDTSFGRGRK GQKGEPGLVP 
VVTGIRGRPG PAGPPGSQGP RGDRGPKGRP GPRGPQGIDG EPGVPGQPGA PGPPGHPSHP 
GPDGMSRPFS AQMAGLDEKS GLGSQVGLMP GSVGPVGPRG PQGLQGQQGG VGPAGPPGEP 
GEPGPMGPIG SRGPEGPPGK PGEDGEPGRN GNTGEVGFSG SPGARGFPGA PGLPGLKGHR 
GHKGLEGPKG EIGAPGAKGE AGPTGPMGAM GPLGPRGMPG ERGRLGPQGA PGKRGAHGMP 
GKPGPMGPLG IPGSSGFPGN PGMKGEAGPT GARGPEGPQG QRGETGPPGP AGSQGLPGAV 
GTDGTPGAKG PTGSAGTSGP PGLAGPPGSP GPQGSTGPQG IRGQSGDPGV PGFKGEAGPK 
GEPGPHGIQG PIGPPGEEGK RGPRGDPGTV GPPGPMGERG APGNRGFPGS DGLPGPKGAQ 
GERGPVGSSG PKGGQGDPGR PGEPGLPGAR GLTGNPGVQG PEGKLGPLGA PGEDGRPGPP 
GSIGIRGQPG SMGLPGPKGS SGDLGKPGEA GNAGVPGQRG APGKDGEVGP SGPVGPPGLA 
GERGEQGPPG PTGFQGLPGP PGPPGEGGKA GDQGVPGEPG AVGPLGPRGE RGNPGERGEP 
GITGLPGEKG MAGGHGPDGP KGNPGPTGTI GDTGPPGLQG MPGERGIAGT PGPKGDRGGI 
GEKGAEGTAG NDGARGLPGP LGPPGPAGPT GEKGEPGPRG LVGPPGSRGN PGSRGENGPT 
GAVGFAGPQG PDGQPGVKGE PGEPGQKGDA GSPGPQGLAG SPGPHGPHGV PGLKGGRGTQ 
GPPGATGFPG SAGRVGPPGP AGAPGPAGPA GEPGKEGPPG LRGDPGSHGR VGDRGPAGPP 
GSPGDKGDPG EDGQPGPDGP PGPAGTTGQR GIVGMPGQRG ERGMPGLPGP AGTPGKVGPT 
GATGDKGPPG PVGPPGSNGP VGEPGPEGPA GNDGTPGRDG AVGERGDRGD PGPAGLPGSQ 
GAPGTPGPVG APGDAGQRGE PGSRGPVGPP GRAGKRGLPG PQGPRGDKGD NGDRGDRGQK 
GHRGFTGLQG LPGPPGPNGE QGSAGIPGPF GPRGPPGPVG PSGKEGNPGP LGPIGPPGVR 
GSVGEAGPEG PPGEPGPPGP PGPPGHLTAA LGDIMGHYDE NMPDPLPEFT EDQAAPDDTN 
KTDPGIHVTL KSLSSQIETM RSPDGSKKHP ARTCDDLKLC HPTKQSGEYW IDPNQGSAED 
AIKVYCNMET GETCISANPA SVPRKTWWAS KSPDNKPVWY GLDMNRGSQF TYGDYQSPNT 
AITQMTFLRL LSKEASQNLT YICRNTVGYM DDQAKNLKKA VVLKGSNDLE IKGEGNIRFR 
YTVLQDTCSK RNGNVGKTIF EYRTQNVARL PIIDVGPVDI GNADQEFGLD IGPVCFM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Col5a2

Associated with

Other Information

Localization of pro-alpha 2(V) collagen transcripts in the tissues of the developing mouse embryo. PubMed ID: 1297453

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Targeted mutation in the col5a2 gene reveals a regulatory role for type V collagen during matrix assembly. PubMed ID: 7704020

Effect of targeted mutation in collagen V alpha 2 gene on development of cutaneous hyperplasia in tight skin mice. PubMed ID: 9642685