Genular: Defining Cellular Identity and Function

Details for: Col1a2

Gene ID: 12843

Symbol: Col1a2

Ensembl ID: ENSMUSG00000029661

Description: collagen, type I, alpha 2

Associated with

Adaptive immune system
(R-MMU-1280218)
Assembly of collagen fibrils and other multimeric structures
(R-MMU-2022090)
Cell surface interactions at the vascular wall
(R-MMU-202733)
Collagen biosynthesis and modifying enzymes
(R-MMU-1650814)
Collagen chain trimerization
(R-MMU-8948216)
Collagen degradation
(R-MMU-1442490)
Collagen formation
(R-MMU-1474290)
Crosslinking of collagen fibrils
(R-MMU-2243919)
Degradation of the extracellular matrix
(R-MMU-1474228)
Ecm proteoglycans
(R-MMU-3000178)
Gp1b-ix-v activation signalling
(R-MMU-430116)
Gpvi-mediated activation cascade
(R-MMU-114604)
Hemostasis
(R-MMU-109582)
Immune system
(R-MMU-168256)
Immunoregulatory interactions between a lymphoid and a non-lymphoid cell
(R-MMU-198933)
Integrin cell surface interactions
(R-MMU-216083)
Met activates ptk2 signaling
(R-MMU-8874081)
Met promotes cell motility
(R-MMU-8875878)
Non-integrin membrane-ecm interactions
(R-MMU-3000171)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet adhesion to exposed collagen
(R-MMU-75892)
Platelet aggregation (plug formation)
(R-MMU-76009)
Signaling by met
(R-MMU-6806834)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signal transduction
(R-MMU-162582)
Blood vessel development
(GO:0001568)
Bone mineralization
(GO:0030282)
Cellular response to amino acid stimulus
(GO:0071230)
Collagen-containing extracellular matrix
(GO:0062023)
Collagen fibril organization
(GO:0030199)
Collagen metabolic process
(GO:0032963)
Collagen trimer
(GO:0005581)
Collagen type i trimer
(GO:0005584)
Extracellular matrix assembly
(GO:0085029)
Extracellular matrix organization
(GO:0030198)
Extracellular matrix structural constituent
(GO:0005201)
Extracellular matrix structural constituent conferring tensile strength
(GO:0030020)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Identical protein binding
(GO:0042802)
Metal ion binding
(GO:0046872)
Platelet-derived growth factor binding
(GO:0048407)
Protease binding
(GO:0002020)
Protein-macromolecule adaptor activity
(GO:0030674)
Protein binding
(GO:0005515)
Protein heterotrimerization
(GO:0070208)
Regulation of blood pressure
(GO:0008217)
Rho protein signal transduction
(GO:0007266)
Skeletal system development
(GO:0001501)
Skin morphogenesis
(GO:0043589)
Smad binding
(GO:0046332)
Transforming growth factor beta receptor signaling pathway
(GO:0007179)

Other Information

Proteins

Collagen alpha-2(I) chain

Genular Protein ID: 2190358975

Symbol: CO1A2_MOUSE

Name: Collagen alpha-2(I) chain

UniProtKB Accession Codes:

Q01149 Q8CGA5

Database IDs:

Citations:

PubMed ID: 1505972

Title: Sequence analysis of a full-length cDNA for the murine pro alpha 2(I) collagen chain: comparison of the derived primary structure with human pro alpha 2(I) collagen.

PubMed ID: 1505972

DOI: 10.1016/0888-7543(92)90065-z

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1748823

Title: Construction of a full-length murine pro alpha 2(I) collagen cDNA by the polymerase chain reaction.

PubMed ID: 1748823

DOI: 10.1111/1523-1747.ep12491894

PubMed ID: 3039494

Title: Identification of a cell-specific transcriptional enhancer in the first intron of the mouse alpha 2 (type I) collagen gene.

PubMed ID: 3039494

DOI: 10.1073/pnas.84.16.5590

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20713358

Title: Post-transcriptional up-regulation of Tsc-22 by Ybx1, a target of miR-216a, mediates TGF-{beta}-induced collagen expression in kidney cells.

PubMed ID: 20713358

DOI: 10.1074/jbc.m110.165027

Sequence Information:

Length: 1372
Mass: 129557
Checksum: 0D17DF5D6C1452D1
Sequence:

MLSFVDTRTL LLLAVTSCLA TCQYLQSGSV RKGPTGDRGP RGQRGPAGPR GRDGVDGPMG 
PPGPPGSPGP PGSPAPPGLT GNFAAQYSDK GVSSGPGPMG LMGPRGPPGA VGAPGPQGFQ 
GPAGEPGEPG QTGPAGPRGP AGSPGKAGED GHPGKPGRPG ERGVVGPQGA RGFPGTPGLP 
GFKGVKGHSG MDGLKGQPGA QGVKGEPGAP GENGTPGQAG ARGLPGERGR VGAPGPAGAR 
GSDGSVGPVG PAGPIGSAGP PGFPGAPGPK GELGPVGNPG PAGPAGPRGE VGLPGLSGPV 
GPPGNPGTNG LTGAKGATGL PGVAGAPGLP GPRGIPGPAG AAGATGARGL VGEPGPAGSK 
GESGNKGEPG SVGAQGPPGP SGEEGKRGSP GEAGSAGPAG PPGLRGSPGS RGLPGADGRA 
GVMGPPGNRG STGPAGIRGP NGDAGRPGEP GLMGPRGLPG SPGNVGPSGK EGPVGLPGID 
GRPGPIGPAG PRGEAGNIGF PGPKGPSGDP GKPGERGHPG LAGARGAPGP DGNNGAQGPP 
GPQGVQGGKG EQGPAGPPGF QGLPGPSGTT GEVGKPGERG LPGEFGLPGP AGPRGERGTP 
GESGAAGPSG PIGSRGPSGA PGPDGNKGEA GAVGAPGSAG ASGPGGLPGE RGAAGIPGGK 
GEKGETGLRG DTGNTGRDGA RGIPGAVGAP GPAGASGDRG EAGAAGPSGP AGPRGSPGER 
GEVGPAGPNG FAGPAGAAGQ PGAKGEKGTK GPKGENGIVG PTGSVGAAGP SGPNGPPGPV 
GSRGDGGPPG MTGFPGAAGR TGPPGPSGIA GPPGPPGAAG KEGIRGPRGD QGPVGRTGET 
GASGPPGFVG EKGPSGEPGT AGAPGTAGPQ GLLGAPGILG LPGSRGERGL PGIAGALGEP 
GPLGISGPPG ARGPPGAVGS PGVNGAPGEA GRDGNPGSDG PPGRDGQPGH KGERGYPGSI 
GPTGAAGAPG PHGSVGPAGK HGNRGEPGPA GSVGPVGAVG PRGPSGPQGI RGDKGEPGDK 
GHRGLPGLKG YSGLQGLPGL AGLHGDQGAP GPVGPAGPRG PAGPSGPVGK DGRSGQPGPV 
GPAGVRGSQG SQGPAGPPGP PGPPGPPGVS GGGYDFGFEG DFYRADQPRS QPSLRPKDYE 
VDATLKSLNN QIETLLTPEG SRKNPARTCR DLRLSHPEWN SDYYWIDPNQ GCTMDAIKVY 
CDFSTGETCI QAQPVNTPAK NSYSRAQANK HVWLGETING GSQFEYNVEG VSSKEMATQL 
AFMRLLANRA SQNITYHCKN SIAYLDEETG SLNKAVLLQG SNDVELVAEG NSRFTYSVLV 
DGCSKKTNEW GKTIIEYKTN KPSRLPFLDI APLDIGGADQ EFRVEVGPVC FK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Col1a2

Associated with

Other Information

Sequence analysis of a full-length cDNA for the murine pro alpha 2(I) collagen chain: comparison of the derived primary structure with human pro alpha 2(I) collagen. PubMed ID: 1505972

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Construction of a full-length murine pro alpha 2(I) collagen cDNA by the polymerase chain reaction. PubMed ID: 1748823

Identification of a cell-specific transcriptional enhancer in the first intron of the mouse alpha 2 (type I) collagen gene. PubMed ID: 3039494

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079