Details for: COL4A5

Gene ID: 1287

Symbol: COL4A5

Ensembl ID: ENSG00000188153

Description: collagen type IV alpha 5 chain

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 56.5107
    Cell Significance Index: -26.6800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 24.3521
    Cell Significance Index: -23.2500
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 12.9755
    Cell Significance Index: 115.1800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.9333
    Cell Significance Index: -21.7400
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 4.5497
    Cell Significance Index: 28.0700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 4.5457
    Cell Significance Index: 62.0200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 2.4505
    Cell Significance Index: 62.9900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 2.1720
    Cell Significance Index: 69.5700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 2.1442
    Cell Significance Index: 164.5400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.0411
    Cell Significance Index: 106.0300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.6769
    Cell Significance Index: 94.1000
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 1.6728
    Cell Significance Index: 10.3000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.4451
    Cell Significance Index: 655.9000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.4413
    Cell Significance Index: 39.2300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.1370
    Cell Significance Index: 225.6400
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.1253
    Cell Significance Index: 17.1200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.0714
    Cell Significance Index: 1975.9500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.0223
    Cell Significance Index: 1573.7400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.9471
    Cell Significance Index: 1287.8000
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.6812
    Cell Significance Index: 16.6200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.6441
    Cell Significance Index: 18.0000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.5672
    Cell Significance Index: 69.7400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4826
    Cell Significance Index: 86.9900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.4270
    Cell Significance Index: 44.4600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4089
    Cell Significance Index: 77.8200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3834
    Cell Significance Index: 17.3800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.3623
    Cell Significance Index: 230.0700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.3556
    Cell Significance Index: 5.2500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.3175
    Cell Significance Index: 597.8400
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: 0.1588
    Cell Significance Index: 2.3800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1480
    Cell Significance Index: 65.4400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1401
    Cell Significance Index: 126.4900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1103
    Cell Significance Index: 2.9600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0909
    Cell Significance Index: 12.4800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0894
    Cell Significance Index: 48.8100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0481
    Cell Significance Index: 4.7600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0464
    Cell Significance Index: 7.5400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0236
    Cell Significance Index: 2.5700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0140
    Cell Significance Index: 9.6900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0015
    Cell Significance Index: -1.1100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0236
    Cell Significance Index: -17.2800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0365
    Cell Significance Index: -27.6000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0371
    Cell Significance Index: -2.2300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0398
    Cell Significance Index: -1.4000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0429
    Cell Significance Index: -24.1800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0431
    Cell Significance Index: -6.2700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0435
    Cell Significance Index: -3.2400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0440
    Cell Significance Index: -15.8000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0543
    Cell Significance Index: -33.8900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0590
    Cell Significance Index: -1.7000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0604
    Cell Significance Index: -12.1200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0684
    Cell Significance Index: -4.8400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0715
    Cell Significance Index: -20.5900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0768
    Cell Significance Index: -4.7100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1039
    Cell Significance Index: -12.1100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1188
    Cell Significance Index: -2.9700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1283
    Cell Significance Index: -27.0300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1461
    Cell Significance Index: -3.1600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1543
    Cell Significance Index: -26.3400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1847
    Cell Significance Index: -12.7800
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.1866
    Cell Significance Index: -2.6100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1944
    Cell Significance Index: -25.1100
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.2002
    Cell Significance Index: -2.8500
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.2155
    Cell Significance Index: -2.7600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.2335
    Cell Significance Index: -29.9400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2483
    Cell Significance Index: -25.3700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.2506
    Cell Significance Index: -5.7900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2579
    Cell Significance Index: -29.5500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2762
    Cell Significance Index: -5.7300
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.2845
    Cell Significance Index: -3.0500
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: -0.3204
    Cell Significance Index: -3.6900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3294
    Cell Significance Index: -17.1600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3294
    Cell Significance Index: -26.0900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3363
    Cell Significance Index: -15.6800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3454
    Cell Significance Index: -5.7800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3595
    Cell Significance Index: -18.1700
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -0.3645
    Cell Significance Index: -2.6500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.3682
    Cell Significance Index: -6.3100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3740
    Cell Significance Index: -22.9900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3920
    Cell Significance Index: -26.3600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.4216
    Cell Significance Index: -19.8200
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.4230
    Cell Significance Index: -2.5100
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.4241
    Cell Significance Index: -7.3300
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.4405
    Cell Significance Index: -10.6700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4461
    Cell Significance Index: -11.7300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4932
    Cell Significance Index: -17.1400
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.5002
    Cell Significance Index: -15.8200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.5261
    Cell Significance Index: -11.2100
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: -0.5526
    Cell Significance Index: -4.9800
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.5576
    Cell Significance Index: -7.1500
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.5769
    Cell Significance Index: -3.6200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.5888
    Cell Significance Index: -37.1100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.6114
    Cell Significance Index: -5.6300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.6346
    Cell Significance Index: -28.0700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6497
    Cell Significance Index: -34.1100
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: -0.6950
    Cell Significance Index: -4.3000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.7079
    Cell Significance Index: -24.8000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.7502
    Cell Significance Index: -28.4100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.7786
    Cell Significance Index: -20.7900
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.7844
    Cell Significance Index: -19.5600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structural Role:** COL4A5 is a non-collagenous protein that forms part of the collagen type IV network, which is essential for maintaining tissue integrity and function. 2. **Cellular Expression:** COL4A5 is expressed in a variety of cell types, including epithelial cells, fibroblasts, and oligodendrocytes, highlighting its importance in different tissues and cell types. 3. **Evolutionary Conservation:** COL4A5 is highly conserved across species, suggesting its critical role in fundamental biological processes. 4. **Regulatory Mechanisms:** COL4A5 is subject to various regulatory mechanisms, including post-translational modifications, alternative splicing, and transcriptional control. **Pathways and Functions:** 1. **Anchoring Fibril Formation:** COL4A5 plays a crucial role in the formation of anchoring fibrils, which are essential for maintaining tissue integrity and preventing ECM degradation. 2. **Basement Membrane Formation:** COL4A5 is a key component of the basement membrane, a thin layer of ECM that separates epithelial and endothelial cells from underlying tissues. 3. **Collagen Fibril Assembly:** COL4A5 is involved in the assembly of collagen fibrils, which provides structural support to the ECM. 4. **ECM Organization:** COL4A5 helps regulate ECM organization, modulating the deposition and degradation of ECM components. 5. **Cell Signaling:** COL4A5 interacts with various signaling molecules, including integrins, laminins, and growth factors, influencing cellular behaviors such as migration, proliferation, and differentiation. **Clinical Significance:** 1. **Cancer:** Alterations in COL4A5 expression have been linked to various cancers, including prostate cancer, breast cancer, and lung cancer. 2. **Fibrosis:** COL4A5 is involved in the pathogenesis of fibrotic diseases, such as pulmonary fibrosis and liver fibrosis. 3. **Neurological Disorders:** COL4A5 has been implicated in neurological disorders, including multiple sclerosis, Alzheimer's disease, and Parkinson's disease. 4. **Wound Healing:** COL4A5 is essential for wound healing, as it regulates ECM remodeling and tissue repair. 5. **Regenerative Medicine:** COL4A5 has potential applications in regenerative medicine, as it can be used to develop novel therapeutics and tissue engineering strategies. In conclusion, COL4A5 is a critical component of the extracellular matrix that plays a vital role in maintaining tissue structure and function. Its dysregulation has been implicated in various diseases, highlighting the need for further research into the molecular mechanisms underlying COL4A5 function and its potential therapeutic applications.

Genular Protein ID: 2185934490

Symbol: CO4A5_HUMAN

Name: Collagen alpha-5(IV) chain

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8120014

Title: Structure of the human type IV collagen COL4A5 gene.

PubMed ID: 8120014

DOI: 10.1016/s0021-9258(17)37416-1

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 1352287

Title: Complete amino acid sequence of the human alpha 5 (IV) collagen chain and identification of a single-base mutation in exon 23 converting glycine 521 in the collagenous domain to cysteine in an Alport syndrome patient.

PubMed ID: 1352287

DOI: 10.1016/s0021-9258(18)42301-0

PubMed ID: 2380186

Title: Complete primary structure of the triple-helical region and the carboxyl-terminal domain of a new type IV collagen chain, alpha 5(IV).

PubMed ID: 2380186

DOI: 10.1016/s0021-9258(18)77414-0

PubMed ID: 2004755

Title: Characterization of the 3' half of the human type IV collagen alpha 5 gene that is affected in the Alport syndrome.

PubMed ID: 2004755

DOI: 10.1016/0888-7543(91)90214-y

PubMed ID: 1689491

Title: Identification of a distinct type IV collagen alpha chain with restricted kidney distribution and assignment of its gene to the locus of X chromosome-linked Alport syndrome.

PubMed ID: 1689491

DOI: 10.1073/pnas.87.4.1606

PubMed ID: 2339699

Title: Molecular cloning of alpha 5(IV) collagen and assignment of the gene to the region of the X chromosome containing the Alport syndrome locus.

PubMed ID: 2339699

PubMed ID: 8301933

Title: Differential splicing of COL4A5 mRNA in kidney and white blood cells: a complex mutation in the COL4A5 gene of an Alport patient deletes the NC1 domain.

PubMed ID: 8301933

DOI: 10.1038/ki.1993.384

PubMed ID: 7853788

Title: Mutations in the COL4A5 gene in Alport syndrome: a possible mutation in primordial germ cells.

PubMed ID: 7853788

DOI: 10.1038/ki.1994.399

PubMed ID: 9195222

Title: The clinical spectrum of type IV collagen mutations.

PubMed ID: 9195222

DOI: 10.1002/(sici)1098-1004(1997)9:6<477::aid-humu1>3.0.co;2-#

PubMed ID: 1672282

Title: Single base mutation in alpha 5(IV) collagen chain gene converting a conserved cysteine to serine in Alport syndrome.

PubMed ID: 1672282

DOI: 10.1016/0888-7543(91)90215-z

PubMed ID: 1376965

Title: Substitution of arginine for glycine 325 in the collagen alpha 5 (IV) chain associated with X-linked Alport syndrome: characterization of the mutation by direct sequencing of PCR-amplified lymphoblast cDNA fragments.

PubMed ID: 1376965

PubMed ID: 1363780

Title: De novo mutation in the COL4A5 gene converting glycine 325 to glutamic acid in Alport syndrome.

PubMed ID: 1363780

DOI: 10.1093/hmg/1.2.127

PubMed ID: 8406498

Title: Identification of four novel mutations in the COL4A5 gene of patients with Alport syndrome.

PubMed ID: 8406498

DOI: 10.1006/geno.1993.1351

PubMed ID: 8356449

Title: Deletion of the paired alpha 5(IV) and alpha 6(IV) collagen genes in inherited smooth muscle tumors.

PubMed ID: 8356449

DOI: 10.1126/science.8356449

PubMed ID: 7599631

Title: Detection of 12 novel mutations in the collagenous domain of the COL4A5 gene in Alport syndrome patients.

PubMed ID: 7599631

DOI: 10.1002/humu.1380050303

PubMed ID: 8651292

Title: A mutation causing Alport syndrome with tardive hearing loss is common in the western United States.

PubMed ID: 8651292

PubMed ID: 8651296

Title: X-linked Alport syndrome: an SSCP-based mutation survey over all 51 exons of the COL4A5 gene.

PubMed ID: 8651296

PubMed ID: 8940267

Title: Spectrum of mutations in the COL4A5 collagen gene in X-linked Alport syndrome.

PubMed ID: 8940267

PubMed ID: 8829632

Title: Substitution of A1498D in noncollagen domain of a5(IV) collagen chain associated with adult-onset X-linked Alport syndrome.

PubMed ID: 8829632

DOI: 10.1002/(sici)1098-1004(1996)7:2<149::aid-humu9>3.0.co;2-7

PubMed ID: 9150741

Title: Common ancestry of three Ashkenazi-American families with Alport syndrome and COL4A5 R1677Q.

PubMed ID: 9150741

DOI: 10.1007/s004390050429

PubMed ID: 9452056

Title: Missense mutations in the COL4A5 gene in patients with X-linked Alport syndrome.

PubMed ID: 9452056

DOI: 10.1002/humu.1380110135

PubMed ID: 9848783

Title: High mutation detection rate in the COL4A5 collagen gene in suspected Alport syndrome using PCR and direct DNA sequencing.

PubMed ID: 9848783

DOI: 10.1681/asn.v9122291

PubMed ID: 10561141

Title: Detection of mutations in the COL4A5 gene in over 90% of male patients with X-linked Alport's syndrome by RT-PCR and direct sequencing.

PubMed ID: 10561141

DOI: 10.1016/s0272-6386(99)70042-9

PubMed ID: 10563487

Title: Three novel mutations in the COL4A5 gene in Mexican Alport syndrome patients.

PubMed ID: 10563487

DOI: 10.1034/j.1399-0004.1999.560312.x

PubMed ID: 10094548

Title: Detection of mutations in COL4A5 in patients with Alport syndrome.

PubMed ID: 10094548

DOI: 10.1002/(sici)1098-1004(1999)13:2<124::aid-humu4>3.0.co;2-z

PubMed ID: 11004279

Title: Dot-and-fleck retinopathy in Alport syndrome caused by a novel mutation in the COL4A5 gene.

PubMed ID: 11004279

DOI: 10.1016/s0002-9394(00)00466-9

PubMed ID: 10862091

Title: Spectrum of COL4A5 mutations in Finnish Alport syndrome patients.

PubMed ID: 10862091

DOI: 10.1002/1098-1004(200006)15:6<579::aid-humu13>3.0.co;2-k

PubMed ID: 10684360

Title: Mutational analysis of COL4A5 gene in Korean Alport syndrome.

PubMed ID: 10684360

DOI: 10.1007/s004670050025

PubMed ID: 11223851

Title: Efficient detection of Alport syndrome COL4A5 mutations with multiplex genomic PCR-SSCP.

PubMed ID: 11223851

DOI: 10.1002/1096-8628(20010115)98:2<148::aid-ajmg1024>3.0.co;2-w

PubMed ID: 12784310

Title: Alport syndrome with diffuse leiomyomatosis.

PubMed ID: 12784310

DOI: 10.1002/ajmg.a.20019

PubMed ID: 24522658

Title: Identification of a novel COL4A5 mutation in a Chinese family with X-linked Alport syndrome using exome sequencing.

PubMed ID: 24522658

DOI: 10.1007/s11033-014-3227-1

Sequence Information:

  • Length: 1685
  • Mass: 161044
  • Checksum: 4450A6762F12A626
  • Sequence:
  • MKLRGVSLAA GLFLLALSLW GQPAEAAACY GCSPGSKCDC SGIKGEKGER GFPGLEGHPG 
    LPGFPGPEGP PGPRGQKGDD GIPGPPGPKG IRGPPGLPGF PGTPGLPGMP GHDGAPGPQG 
    IPGCNGTKGE RGFPGSPGFP GLQGPPGPPG IPGMKGEPGS IIMSSLPGPK GNPGYPGPPG 
    IQGLPGPTGI PGPIGPPGPP GLMGPPGPPG LPGPKGNMGL NFQGPKGEKG EQGLQGPPGP 
    PGQISEQKRP IDVEFQKGDQ GLPGDRGPPG PPGIRGPPGP PGGEKGEKGE QGEPGKRGKP 
    GKDGENGQPG IPGLPGDPGY PGEPGRDGEK GQKGDTGPPG PPGLVIPRPG TGITIGEKGN 
    IGLPGLPGEK GERGFPGIQG PPGLPGPPGA AVMGPPGPPG FPGERGQKGD EGPPGISIPG 
    PPGLDGQPGA PGLPGPPGPA GPHIPPSDEI CEPGPPGPPG SPGDKGLQGE QGVKGDKGDT 
    CFNCIGTGIS GPPGQPGLPG LPGPPGSLGF PGQKGEKGQA GATGPKGLPG IPGAPGAPGF 
    PGSKGEPGDI LTFPGMKGDK GELGSPGAPG LPGLPGTPGQ DGLPGLPGPK GEPGGITFKG 
    ERGPPGNPGL PGLPGNIGPM GPPGFGPPGP VGEKGIQGVA GNPGQPGIPG PKGDPGQTIT 
    QPGKPGLPGN PGRDGDVGLP GDPGLPGQPG LPGIPGSKGE PGIPGIGLPG PPGPKGFPGI 
    PGPPGAPGTP GRIGLEGPPG PPGFPGPKGE PGFALPGPPG PPGLPGFKGA LGPKGDRGFP 
    GPPGPPGRTG LDGLPGPKGD VGPNGQPGPM GPPGLPGIGV QGPPGPPGIP GPIGQPGLHG 
    IPGEKGDPGP PGLDVPGPPG ERGSPGIPGA PGPIGPPGSP GLPGKAGASG FPGTKGEMGM 
    MGPPGPPGPL GIPGRSGVPG LKGDDGLQGQ PGLPGPTGEK GSKGEPGLPG PPGPMDPNLL 
    GSKGEKGEPG LPGIPGVSGP KGYQGLPGDP GQPGLSGQPG LPGPPGPKGN PGLPGQPGLI 
    GPPGLKGTIG DMGFPGPQGV EGPPGPSGVP GQPGSPGLPG QKGDKGDPGI SSIGLPGLPG 
    PKGEPGLPGY PGNPGIKGSV GDPGLPGLPG TPGAKGQPGL PGFPGTPGPP GPKGISGPPG 
    NPGLPGEPGP VGGGGHPGQP GPPGEKGKPG QDGIPGPAGQ KGEPGQPGFG NPGPPGLPGL 
    SGQKGDGGLP GIPGNPGLPG PKGEPGFHGF PGVQGPPGPP GSPGPALEGP KGNPGPQGPP 
    GRPGLPGPEG PPGLPGNGGI KGEKGNPGQP GLPGLPGLKG DQGPPGLQGN PGRPGLNGMK 
    GDPGLPGVPG FPGMKGPSGV PGSAGPEGEP GLIGPPGPPG LPGPSGQSII IKGDAGPPGI 
    PGQPGLKGLP GPQGPQGLPG PTGPPGDPGR NGLPGFDGAG GRKGDPGLPG QPGTRGLDGP 
    PGPDGLQGPP GPPGTSSVAH GFLITRHSQT TDAPQCPQGT LQVYEGFSLL YVQGNKRAHG 
    QDLGTAGSCL RRFSTMPFMF CNINNVCNFA SRNDYSYWLS TPEPMPMSMQ PLKGQSIQPF 
    ISRCAVCEAP AVVIAVHSQT IQIPHCPQGW DSLWIGYSFM MHTSAGAEGS GQALASPGSC 
    LEEFRSAPFI ECHGRGTCNY YANSYSFWLA TVDVSDMFSK PQSETLKAGD LRTRISRCQV 
    CMKRT

Genular Protein ID: 3043529338

Symbol: Q49AM6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

Sequence Information:

  • Length: 695
  • Mass: 64324
  • Checksum: 91FAB53FB30A3120
  • Sequence:
  • MGPPGPPGFP GERGQKGDEG PPGISIPGPP GLDGQPGAPG LPGPPGPAGP HIPPSDEICE 
    PGPPGPPGSP GDKGLQGEQG VKGDKGDTCF NCIGTGISGP PGQPGLPGLP GPPGSLGFPG 
    QKGEKGQAGA TGPKGLPGIP GAPGAPGFPG SKGEPGDILT FPGMKGDKGE LGSPGAPGLP 
    GLPGTPGQDG LPGLPGPKGE PGGITFKGER GPPGNPGLPG LPGNIGPMGP PGFGPPGPVG 
    EKGIQGVAGN PGQPGIPGPK GDPGQTITQP GKPGLPGNPG RDGDVGLPGD PGLPGQPGLP 
    GIPGSKGEPG IPGIGLPGPP GPKGFPGIPG PPGAPGTPGR IGLEGPPGPP GFPGPKGEPG 
    FALPGPPGPP GLPGFKGALG PKGDRGFPGP PGPPGRTGLD GLPGPKGDVG PNGQPGPMGP 
    PGLPGIGVQG PPGPPGIPGP IGQPGLHGIP GEKGDPGPPG LDVPGPPGER GSPGIPGAPG 
    PIGPPGSPGL PGKAGASGFP GTKGEMGMMG PPGPPGPLGI PGRSGVPGLK GDDGLQGQPG 
    LPGPTGEKGS KGEPGLPGPP GPMDPNLLGS KGEKGEPGLP GIPGVSGPKG YQGLPGDPGQ 
    PGLSGQPGLP GPPGPKGNPG LPGQPGLIGP PGLKGTIGDM GFPGPQGVEG PPGPSGVPGQ 
    PGSPGLPGQK GDKGDPGISS IGLPGLPGPK VIFGI

Genular Protein ID: 993533887

Symbol: A7MBN3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1691
  • Mass: 161790
  • Checksum: 8241484AE676D9AB
  • Sequence:
  • MKLRGVSLAA GLFLLALSLW GQPAEAAACY GCSPGSKCDC SGIKGEKGER GFPGLEGHPG 
    LPGFPGPEGP PGPRGQKGDD GIPGPPGPKG IRGPPGLPGF PGTPGLPGMP GHDGAPGPQG 
    IPGCNGTKGE RGFPGSPGFP GLQGPPGPPG IPGMKGEPGS IIMSSLPGPK GNPGYPGPPG 
    IQGLPGPTGI PGPIGPPGPP GLMGPPGPPG LPGPKGNMGL NFQGPKGEKG EQGLQGPPGP 
    PGQISEQKRP IDVEFQKGDQ GLPGDRGPPG PPGIRGPPGP PGGEKGEKGE QGEPGKRGKP 
    GKDGENGQPG IPGLPGDPGY PGEPGRDGEK GQKGDTGPPG PPGLVIPRPG TGITIGEKGN 
    IGLPGLPGEK GERGFPGIQG PPGLPGPPGA AVMGPPGPPG FPGERGQKGD EGPPGISIPG 
    PPGLDGQPGA PGLPGPPGPA GPHIPPSDEI CEPGPPGPPG SPGDKGLQGE QGVKGDKGDT 
    CFNCIGTGIS GPPGQPGLPG LPGPPGSLGF PGQKGEKGQA GATGPKGLPG IPGAPGAPGF 
    PGSKGEPGDI LTFPGMKGDK GELGSPGAPG LPGLPGTPGQ DGLPGLPGPK GEPGGITFKG 
    ERGPPGNPGL PGLPGNIGPM GPPGFGPPGP VGEKGIQGVA GNPGQPGIPG PKGDPGQTIT 
    QPGKPGLPGN PGRDGDVGLP GDPGLPGQPG LPGIPGSKGE PGIPGIGLHG PPGPKGFPGI 
    PGPPGAPGTP GRIGLEGPPG PPGFPGPKGE PGFALPGPPG PPGLPGFKGA LGPKGDRGFP 
    GPPGPPGRTG LDGLPGPKGD VGPNGQPGPM GPPGLPGIGV QGPPGPPGIP GPIGQPGLHG 
    IPGEKGDPGP PGLDVPGPPG ERGSRGIPGA PGPIGPPGSP GLPGKAGASG FPGTKGEMGM 
    MGPPGPPGPL GIPGRSGVPG LKGDDGLQGQ PGLPGPTGEK GSKGERGLPG PPGPMDPNLL 
    GSKGEKGEPG LPGIPGVSGP KGYQGLPGDP GQPGLSGQPG LPGPPGPKGN PGLPGQPGLI 
    GPPGLKGTIG DMGFPGPQGV EGPPGPSGVP GQPGSPGLPG QKGDKGDPGI SSIGLPGLPG 
    PKGEPGLPGY PGNPGIKGSV GDPGLPGLPG TPGAKGQPGL PGFPGTPGPP GPKGISGPPG 
    NPGLPGEPGP VGGGGHPGQP GPPGEKGKPG QDGIPGPAGQ KGEPGQPGFG NPGPPGLPGL 
    SGQKGDGGLP GIPGNPGLPG PKGEPGFHGF PGVQGPPGPP GSPGPALEGP KGNPGPQGPP 
    GRPGPTGFQG LPGPEGPPGL PGNGGIKGEK GNPGQPGLPG LPGLKGDQGP PGLQGNPGRP 
    GLNGMKGDPG LPGVPGFPGM KGPSGVPGSA GPEGEPGLIG PPGPPGLPGP SGQSIIIKGD 
    AGPPGIPGQP GLKGLPGPQG PQGLPGPTGP PGDPGRNGLP GFDGAGGRKG DPGLPGQPGT 
    RGLDGPPGPD GLQGPPGPPG TSSVAHGFLI TRHSQTTDAP QCPQGTLQVY EGFSLLYVQG 
    NKRAHGQDLG TAGSCLRRFS TMPFMFCNIN NVCNFASRND YSYWLSTPEP MPMSMQPLKG 
    QSIQPFISRC AVCEAPAVVI AVHSQTIQIP HCPQGWDSLW IGYSFMMHTS AGAEGSGQAL 
    ASPGSCLEEF RSAPFIECHG RGTCNYYANS YSFWLATVDV SDMFSKPQSE TLKAGDLRTR 
    ISRCQVCMKR T

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.