Details for: COL4A6

Gene ID: 1288

Symbol: COL4A6

Ensembl ID: ENSG00000197565

Description: collagen type IV alpha 6 chain

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 8.4316
    Cell Significance Index: -8.0500
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 7.5287
    Cell Significance Index: 66.8300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 2.6592
    Cell Significance Index: -5.8200
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: 2.5545
    Cell Significance Index: 29.4200
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 2.3454
    Cell Significance Index: 14.4700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.6673
    Cell Significance Index: 86.6100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.3744
    Cell Significance Index: 37.4100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.2647
    Cell Significance Index: 1719.5800
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.9301
    Cell Significance Index: 13.2400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.8133
    Cell Significance Index: 369.1400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.7089
    Cell Significance Index: 18.6400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.6263
    Cell Significance Index: 1155.0200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.5998
    Cell Significance Index: 923.3100
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.5824
    Cell Significance Index: 8.8600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.5725
    Cell Significance Index: 43.9300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.5694
    Cell Significance Index: 12.1700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3713
    Cell Significance Index: 73.6900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3605
    Cell Significance Index: 44.3300
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 0.2778
    Cell Significance Index: 3.1100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.2631
    Cell Significance Index: 3.5900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.2527
    Cell Significance Index: 14.1800
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.2421
    Cell Significance Index: 3.1000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.2256
    Cell Significance Index: 5.8000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.1675
    Cell Significance Index: 17.4400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1006
    Cell Significance Index: 18.1300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0932
    Cell Significance Index: 41.2100
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 0.0919
    Cell Significance Index: 1.3400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0826
    Cell Significance Index: 1.2200
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.0686
    Cell Significance Index: 1.1000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0414
    Cell Significance Index: 26.2700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0412
    Cell Significance Index: 3.0700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0383
    Cell Significance Index: 72.0500
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.0237
    Cell Significance Index: 0.7500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0213
    Cell Significance Index: 1.5100
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 0.0185
    Cell Significance Index: 0.1100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0118
    Cell Significance Index: 0.3300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0107
    Cell Significance Index: 7.4300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0022
    Cell Significance Index: 0.3000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.0001
    Cell Significance Index: 0.0600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0031
    Cell Significance Index: -0.9000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.0065
    Cell Significance Index: -0.0600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0072
    Cell Significance Index: -1.4400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0096
    Cell Significance Index: -1.3900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0102
    Cell Significance Index: -5.7800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0107
    Cell Significance Index: -7.8700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0108
    Cell Significance Index: -3.8900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0119
    Cell Significance Index: -8.9700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0127
    Cell Significance Index: -1.4800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0154
    Cell Significance Index: -8.4200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0303
    Cell Significance Index: -5.1700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0330
    Cell Significance Index: -6.9600
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.0557
    Cell Significance Index: -0.3500
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -0.0578
    Cell Significance Index: -0.4200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0643
    Cell Significance Index: -8.3100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0700
    Cell Significance Index: -8.0300
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0778
    Cell Significance Index: -1.9400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0862
    Cell Significance Index: -8.8100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0873
    Cell Significance Index: -1.2500
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0881
    Cell Significance Index: -2.1400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1052
    Cell Significance Index: -1.7600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1124
    Cell Significance Index: -6.9100
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: -0.1287
    Cell Significance Index: -1.1700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1292
    Cell Significance Index: -8.6900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1434
    Cell Significance Index: -7.4700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1459
    Cell Significance Index: -3.9100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1565
    Cell Significance Index: -7.3600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1640
    Cell Significance Index: -2.8100
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -0.1658
    Cell Significance Index: -1.6400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1721
    Cell Significance Index: -10.5500
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.1755
    Cell Significance Index: -2.2500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1837
    Cell Significance Index: -8.1300
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: -0.1901
    Cell Significance Index: -1.1700
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.1947
    Cell Significance Index: -4.7500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1957
    Cell Significance Index: -6.8000
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.1965
    Cell Significance Index: -2.6500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1989
    Cell Significance Index: -9.2800
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.2074
    Cell Significance Index: -3.2900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2165
    Cell Significance Index: -8.2000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2366
    Cell Significance Index: -8.2900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2425
    Cell Significance Index: -7.9400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.2518
    Cell Significance Index: -5.2700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2565
    Cell Significance Index: -8.1700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2584
    Cell Significance Index: -6.9000
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.2628
    Cell Significance Index: -3.0600
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.2659
    Cell Significance Index: -2.2600
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2694
    Cell Significance Index: -9.8900
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: -0.2814
    Cell Significance Index: -4.2100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2825
    Cell Significance Index: -8.3200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2861
    Cell Significance Index: -14.4600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2868
    Cell Significance Index: -8.2200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2940
    Cell Significance Index: -7.8700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.3047
    Cell Significance Index: -7.0400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.3048
    Cell Significance Index: -10.7100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3154
    Cell Significance Index: -9.0000
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.3175
    Cell Significance Index: -7.9300
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.3234
    Cell Significance Index: -5.3300
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.3291
    Cell Significance Index: -5.6900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.3307
    Cell Significance Index: -13.5500
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.3310
    Cell Significance Index: -2.7800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3407
    Cell Significance Index: -6.6500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** COL4A6 is a type IV collagen gene, which is characterized by the presence of six alpha chains that assemble into a network of collagen fibrils. The alpha-6 chain is specifically involved in the formation of the basement membrane, a thin layer of tissue that separates epithelial and endothelial cells from the underlying connective tissue. COL4A6 is expressed in various cell types, including anterior lens cells, corneal endothelial cells, and smooth muscle cells of the sphincter of the pupil. **Pathways and Functions** The COL4A6 gene is involved in several cellular processes, including: 1. **Anchoring fibril formation**: COL4A6 plays a crucial role in the formation of anchoring fibrils, which are critical for maintaining the integrity of the basement membrane. 2. **Assembly of collagen fibrils and other multimeric structures**: The alpha-6 chain contributes to the assembly of collagen fibrils and other multimeric structures, such as basement membranes and ECM. 3. **Cell adhesion**: COL4A6 is involved in cell adhesion, particularly in the formation of adherens junctions, which are essential for maintaining tissue structure and function. 4. **Cellular responses to stimuli**: COL4A6 is responsive to various cellular stimuli, including heat shock, amino acid stimulation, and stress, which can affect its expression and function. 5. **Collagen biosynthesis and modifying enzymes**: COL4A6 is involved in the biosynthesis and modification of collagen, which is essential for maintaining ECM integrity and function. **Clinical Significance** Mutations or variations in COL4A6 have been associated with various diseases, including: 1. **Alport syndrome**: A genetic disorder affecting the kidneys, ears, and eyes, characterized by glomerulonephritis, hearing loss, and vision impairment. 2. **Ehlers-Danlos syndrome**: A group of disorders characterized by skin hyperextensibility, joint hypermobility, and tissue fragility. 3. **Bloom syndrome**: A rare genetic disorder characterized by short stature, skin hyperpigmentation, and increased risk of cancer. In conclusion, COL4A6 is a critical gene that plays a vital role in maintaining the integrity and function of various tissues and organs. Its dysregulation or mutations can lead to various diseases, highlighting the importance of understanding the molecular mechanisms underlying its function.

Genular Protein ID: 1681502579

Symbol: CO4A6_HUMAN

Name: Collagen alpha-6(IV) chain

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8125972

Title: Identification of a new collagen IV chain, alpha 6(IV), by cDNA isolation and assignment of the gene to chromosome Xq22, which is the same locus for COL4A5.

PubMed ID: 8125972

DOI: 10.1016/s0021-9258(17)37317-9

PubMed ID: 8175748

Title: Complete primary structure of the sixth chain of human basement membrane collagen, alpha 6(IV). Isolation of the cDNAs for alpha 6(IV) and comparison with five other type IV collagen chains.

PubMed ID: 8175748

DOI: 10.1016/s0021-9258(17)36818-7

PubMed ID: 8661006

Title: Structure of the human type IV collagen COL4A6 gene, which is mutated in Alport syndrome-associated leiomyomatosis.

PubMed ID: 8661006

DOI: 10.1006/geno.1996.0222

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 8356449

Title: Deletion of the paired alpha 5(IV) and alpha 6(IV) collagen genes in inherited smooth muscle tumors.

PubMed ID: 8356449

DOI: 10.1126/science.8356449

PubMed ID: 12784310

Title: Alport syndrome with diffuse leiomyomatosis.

PubMed ID: 12784310

DOI: 10.1002/ajmg.a.20019

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 23714752

Title: Novel form of X-linked nonsyndromic hearing loss with cochlear malformation caused by a mutation in the type IV collagen gene COL4A6.

PubMed ID: 23714752

DOI: 10.1038/ejhg.2013.108

Sequence Information:

  • Length: 1691
  • Mass: 163807
  • Checksum: 9313294D4CE63067
  • Sequence:
  • MLINKLWLLL VTLCLTEELA AAGEKSYGKP CGGQDCSGSC QCFPEKGARG RPGPIGIQGP 
    TGPQGFTGST GLSGLKGERG FPGLLGPYGP KGDKGPMGVP GFLGINGIPG HPGQPGPRGP 
    PGLDGCNGTQ GAVGFPGPDG YPGLLGPPGL PGQKGSKGDP VLAPGSFKGM KGDPGLPGLD 
    GITGPQGAPG FPGAVGPAGP PGLQGPPGPP GPLGPDGNMG LGFQGEKGVK GDVGLPGPAG 
    PPPSTGELEF MGFPKGKKGS KGEPGPKGFP GISGPPGFPG LGTTGEKGEK GEKGIPGLPG 
    PRGPMGSEGV QGPPGQQGKK GTLGFPGLNG FQGIEGQKGD IGLPGPDVFI DIDGAVISGN 
    PGDPGVPGLP GLKGDEGIQG LRGPSGVPGL PALSGVPGAL GPQGFPGLKG DQGNPGRTTI 
    GAAGLPGRDG LPGPPGPPGP PSPEFETETL HNKESGFPGL RGEQGPKGNL GLKGIKGDSG 
    FCACDGGVPN TGPPGEPGPP GPWGLIGLPG LKGARGDRGS GGAQGPAGAP GLVGPLGPSG 
    PKGKKGEPIL STIQGMPGDR GDSGSQGFRG VIGEPGKDGV PGLPGLPGLP GDGGQGFPGE 
    KGLPGLPGEK GHPGPPGLPG NGLPGLPGPR GLPGDKGKDG LPGQQGLPGS KGITLPCIIP 
    GSYGPSGFPG TPGFPGPKGS RGLPGTPGQP GSSGSKGEPG SPGLVHLPEL PGFPGPRGEK 
    GLPGFPGLPG KDGLPGMIGS PGLPGSKGAT GDIFGAENGA PGEQGLQGLT GHKGFLGDSG 
    LPGLKGVHGK PGLLGPKGER GSPGTPGQVG QPGTPGSSGP YGIKGKSGLP GAPGFPGISG 
    HPGKKGTRGK KGPPGSIVKK GLPGLKGLPG NPGLVGLKGS PGSPGVAGLP ALSGPKGEKG 
    SVGFVGFPGI PGLPGIPGTR GLKGIPGSTG KMGPSGRAGT PGEKGDRGNP GPVGIPSPRR 
    PMSNLWLKGD KGSQGSAGSN GFPGPRGDKG EAGRPGPPGL PGAPGLPGII KGVSGKPGPP 
    GFMGIRGLPG LKGSSGITGF PGMPGESGSQ GIRGSPGLPG ASGLPGLKGD NGQTVEISGS 
    PGPKGQPGES GFKGTKGRDG LIGNIGFPGN KGEDGKVGVS GDVGLPGAPG FPGVAGMRGE 
    PGLPGSSGHQ GAIGPLGSPG LIGPKGFPGF PGLHGLNGLP GTKGTHGTPG PSITGVPGPA 
    GLPGPKGEKG YPGIGIGAPG KPGLRGQKGD RGFPGLQGPA GLPGAPGISL PSLIAGQPGD 
    PGRPGLDGER GRPGPAGPPG PPGPSSNQGD TGDPGFPGIP GPKGPKGDQG IPGFSGLPGE 
    LGLKGMRGEP GFMGTPGKVG PPGDPGFPGM KGKAGPRGSS GLQGDPGQTP TAEAVQVPPG 
    PLGLPGIDGI PGLTGDPGAQ GPVGLQGSKG LPGIPGKDGP SGLPGPPGAL GDPGLPGLQG 
    PPGFEGAPGQ QGPFGMPGMP GQSMRVGYTL VKHSQSEQVP PCPIGMSQLW VGYSLLFVEG 
    QEKAHNQDLG FAGSCLPRFS TMPFIYCNIN EVCHYARRND KSYWLSTTAP IPMMPVSQTQ 
    IPQYISRCSV CEAPSQAIAV HSQDITIPQC PLGWRSLWIG YSFLMHTAAG AEGGGQSLVS 
    PGSCLEDFRA TPFIECSGAR GTCHYFANKY SFWLTTVEER QQFGELPVSE TLKAGQLHTR 
    VSRCQVCMKS L

Genular Protein ID: 2815871415

Symbol: A0A087WZY5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

Sequence Information:

  • Length: 1666
  • Mass: 161331
  • Checksum: F39A7D32DDEADF19
  • Sequence:
  • MHPGLWLLLV TLCLTEELAA AGEKSYGKPC GGQDCSGSCQ CFPEKGARGR PGPIGIQGPT 
    GPQGFTGSTG LSGLKGERGF PGLLGPYGPK GDKGPMGVPG FLGINGIPGH PGQPGPRGPP 
    GLDGCNGTQG AVGFPGPDGY PGLLGPPGLP GQKGSKGDPV LAPGSFKGMK GDPGLPGLDG 
    ITGPQGAPGF PGAVGPAGPP GLQGPPGPPG PLGPDGNMGL GFQGEKGVKG DVGLPGPAGP 
    PPSTGELEFM GFPKGKKGSK GEPGPKGFPG ISGPPGFPGL GTTGEKGEKG EKGIPGLPGP 
    RGPMGSEGVQ GPPGQQGKKG TLGFPGLNGF QGIEGQKGDI GLPGPDVFID IDGAVISGNP 
    GDPGVPGLPG LKGDEGIQGL RGPSGVPGLP ALSGVPGALG PQGFPGLKGD QGNPGRTTIG 
    AAGLPGRDGL PGPPGPPGPP SPEFETETLH NKESGFPGLR GEQGPKGNLG LKGIKGDSGF 
    CACDGGVPNT GPPGEPGPPG PWGLIGLPGL KGARGDRGSG GAQGPAGAPG LVGPLGPSGP 
    KGKKGEPILS TIQGMPGDRG DSGSQGFRGV IGEPGKDGVP GLPGLPGLPG DGGQGFPGEK 
    GLPGLPGEKG HPGPPGLPGN GLPGLPGPRG LPGDKGKDGL PGQQGLPGSK GITLPCIIPG 
    SYGPSGFPGT PGFPGPKGSR GLPGTPGQPG SSGSKGEPGS PGLVHLPELP GFPGPRGEKG 
    LPGFPGLPGK DGLPGMIGSP GLPGSKGATG DIFGAENGAP GEQGLQGLTG HKGFLGDSGL 
    PGLKGVHGKP GLLGPKGERG SPGTPGQVGQ PGTPGSSGPY GIKGKSGLPG APGFPGISGH 
    PGKKGTRGKK GPPGSIVKKG LPGLKGLPGN PGLVGLKGSP GSPGVAGLPA LSGPKGEKGS 
    VGFVGFPGIP GLPGIPGTRG LKGIPGSTGK MGPSGRAGTP GEKGDRGNPG PVGIPSPRRP 
    MSNLWLKGDK GSQGSAGSNG FPGPRGDKGE AGRPGPPGLP GAPGLPGIIK GVSGKPGPPG 
    FMGIRGLPGL KGSSGITGFP GMPGESGSQG IRGSPGLPGA SGLPGLKGDN GQTVEISGSP 
    GPKGQPGESG FKGTKGRDGL IGNIGFPGNK GEDGKVGVSG DVGLPGAPGF PGVAGMRGEP 
    GLPGSSGHQG AIGPLGSPGL IGPKGPSITG VPGPAGLPGP KGEKGYPGIG IGAPGKPGLR 
    GQKGDRGFPG LQGPAGLPGA PGISLPSLIA GQPGDPGRPG LDGERGRPGP AGPPGPPGPS 
    SNQGDTGDPG FPGIPGPKGP KGDQGIPGFS GLPGELGLKG MRGEPGFMGT PGKVGPPGDP 
    GFPGMKGKAG PRGSSGLQGD PGQTPTAEAV QVPPGPLGLP GIDGIPGLTG DPGAQGPVGL 
    QGSKGLPGIP GKDGPSGLPG PPGALGDPGL PGLQGPPGFE GAPGQQGPFG MPGMPGQSMR 
    VGYTLVKHSQ SEQVPPCPIG MSQLWVGYSL LFVEGQEKAH NQDLGFAGSC LPRFSTMPFI 
    YCNINEVCHY ARRNDKSYWL STTAPIPMMP VSQTQIPQYI SRCSVCEAPS QAIAVHSQDI 
    TIPQCPLGWR SLWIGYSFLM HTAAGAEGGG QSLVSPGSCL EDFRATPFIE CSGARGTCHY 
    FANKYSFWLT TVEERQQFGE LPVSETLKAG QLHTRVSRCQ VCMKSL

Genular Protein ID: 1196478199

Symbol: A8MXH5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

Sequence Information:

  • Length: 1707
  • Mass: 165468
  • Checksum: BB7E0B93E8C6B1A4
  • Sequence:
  • MHPGLWLLLV TLCLTEELAA AGEKSYGKPC GGQDCSGSCQ CFPEKGARGR PGPIGIQGPT 
    GPQGFTGSTG LSGLKGERGF PGLLGPYGPK GDKGPMGVPG FLGINGIPGH PGQPGPRGPP 
    GLDGCNGTQG AVGFPGPDGY PGLLGPPGLP GQKGSKGDPV LAPGSFKGMK GDPGLPGLDG 
    ITGPQGAPGF PGAVGPAGPP GLQGPPGPPG PLGPDGNMGL GFQGEKGVKG DVGLPGPAGP 
    PPSTGELEFM GFPKGKKGSK GEPGPKGFPG ISGPPGFPGL GTTGEKGEKG EKGIPGLPGP 
    RGPMGSEGVQ GPPGQQGKKG TLGFPGLNGF QGIEGQKGDI GLPGPDVFID IDGAVISGNP 
    GDPGVPGLPG LKGDEGIQGL RGPSGVPGLP ALSGVPGALG PQGFPGLKGD QGNPGRTTIG 
    AAGLPGRDGL PGPPGPPGPP SPEFETETLH NKESGFPGLR GEQGPKGNLG LKGIKGDSGF 
    CACDGGVPNT GPPGEPGPPG PWGLIGLPGL KGARGDRGSG GAQGPAGAPG LVGPLGPSGP 
    KGKKGEPILS TIQGMPGDRG DSGSQGFRGV IGEPGKDGVP GLPGLPGLPG DGGQGFPGEK 
    GLPGLPGEKG HPGPPGLPGN GLPGLPGPRG LPGDKGKDGL PGQQGLPGSK GDCCCREVGK 
    GDLDTERGIT LPCIIPGSYG PSGFPGTPGF PGPKGSRGLP GTPGQPGSSG SKGEPGSPGL 
    VHLPELPGFP GPRGEKGLPG FPGLPGKDGL PGMIGSPGLP GSKGATGDIF GAENGAPGEQ 
    GLQGLTGHKG FLGDSGLPGL KGVHGKPGLL GPKGERGSPG TPGQVGQPGT PGSSGPYGIK 
    GKSGLPGAPG FPGISGHPGK KGTRGKKGPP GSIVKKGLPG LKGLPGNPGL VGLKGSPGSP 
    GVAGLPALSG PKGEKGSVGF VGFPGIPGLP GIPGTRGLKG IPGSTGKMGP SGRAGTPGEK 
    GDRGNPGPVG IPSPRRPMSN LWLKGDKGSQ GSAGSNGFPG PRGDKGEAGR PGPPGLPGAP 
    GLPGIIKGVS GKPGPPGFMG IRGLPGLKGS SGITGFPGMP GESGSQGIRG SPGLPGASGL 
    PGLKGDNGQT VEISGSPGPK GQPGESGFKG TKGRDGLIGN IGFPGNKGED GKVGVSGDVG 
    LPGAPGFPGV AGMRGEPGLP GSSGHQGAIG PLGSPGLIGP KGFPGFPGLH GLNGLPGTKG 
    THGTPGPSIT GVPGPAGLPG PKGEKGYPGI GIGAPGKPGL RGQKGDRGFP GLQGPAGLPG 
    APGISLPSLI AGQPGDPGRP GLDGERGRPG PAGPPGPPGP SSNQGDTGDP GFPGIPGPKG 
    PKGDQGIPGF SGLPGELGLK GMRGEPGFMG TPGKVGPPGD PGFPGMKGKA GPRGSSGLQG 
    DPGQTPTAEA VQVPPGPLGL PGIDGIPGLT GDPGAQGPVG LQGSKGLPGI PGKDGPSGLP 
    GPPGALGDPG LPGLQGPPGF EGAPGQQGPF GMPGMPGQSM RVGYTLVKHS QSEQVPPCPI 
    GMSQLWVGYS LLFVEGQEKA HNQDLGFAGS CLPRFSTMPF IYCNINEVCH YARRNDKSYW 
    LSTTAPIPMM PVSQTQIPQY ISRCSVCEAP SQAIAVHSQD ITIPQCPLGW RSLWIGYSFL 
    MHTAAGAEGG GQSLVSPGSC LEDFRATPFI ECSGARGTCH YFANKYSFWL TTVEERQQFG 
    ELPVSETLKA GQLHTRVSRC QVCMKSL

Genular Protein ID: 3834133229

Symbol: F5H3Q5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

Sequence Information:

  • Length: 1633
  • Mass: 158123
  • Checksum: 153961243B5CF56F
  • Sequence:
  • MHPGLWLLLV TLCLTEELAA AGEKSYGKPC GGQDCSGSCQ CFPEKGARGR PGPIGIQGPT 
    GPQGFTGSTG LSGLKGERGF PGLLGPYGPK GDKGPMGVPG FLGINGIPGH PGQPGPRGPP 
    GLDGCNGTQG AVGFPGPDGY PGLLGPPGLP GQKGSKGDPV LAPGSFKGMK GDPGLPGLDG 
    ITGPQGAPGF PGAVGPAGPP GLQGPPGPPG PLGPDGNMGL GFQGEKGVKG DVGLPGPAGP 
    PPSTGELEFM GFPKGKKGSK GEPGPKGFPG ISGPPGFPGL GTTGEKGEKG EKGIPGLPGP 
    RGPMGSEGVQ GPPGQQGKKG TLGFPGLNGF QGIEGQKGDI GLPGPDVFID IDGAVISGNP 
    GDPGVPGLPG LKGDEGIQGL RGPSGVPGLP ALSGVPGALG PQGFPGLKGD QGNPGRTTIG 
    AAGLPGRDGL PGPPGPPGPP SPEFETETLH NKESGFPGLR GEQGPKGNLG LKGIKGDSGF 
    CACDGGVPNT GPPGEPGPPG PWGLIGLPGL KGARGDRGSG GAQGPAGAPG LVGPLGPSGP 
    KGKKGEPILS TIQGMPGDRG DSGSQGFRGV IGEPGKDGVP GLPGLPGLPG DGGQGFPGEK 
    GLPGLPGEKG HPGPPGLPGN GLPGLPGPRG LPGDKGKDGL PGQQGLPGSK GITLPCIIPG 
    SYGPSGFPGT PGFPGPKGSR GLPGTPGQPG SSGSKGEPGS PGLVHLPELP GFPGPRGEKG 
    LPGFPGLPGK DGLPGMIGSP GLPGSKGATG DIFGAENGAP GEQGLQGLTG HKGFLGDSGL 
    PGLKGVHGKP GLLGPKGERG SPGTPGQVGQ PGTPGSSGPY GIKGKSGLPG APGFPGISGH 
    PGKKGTRGKK GPPGSIVKKG LPGLKGLPGN PGLVGLKGSP GSPGVAGLPA LSGPKGEKGS 
    VGFVGFPGIP GLPGIPGTRG LKGIPGSTGK MGPSGRAGTP GEKGDRGNPG PVGIPSPRRP 
    MSNLWLKGDK GSQGSAGSNG FPGPRGDKGE AGRPGPPGLP GAPGLPGIIK GVSGKPGPPG 
    FMGIRGLPGL KGSSGITGFP GMPGESGSQG IRGSPGLPGA SGLPGLKGDN GQTVEISGSP 
    GPKGQPGESG FKGTKGRDGL IGNIGFPGNK GEDGKVGVSG DVGLPGAPGF PGVAGMRGEP 
    GLPGSSGHQG AIGPLGSPGL IGPKGPSITG VPGPAGLPGP KGEKGYPGIG IGAPGKPGLR 
    GQKGDRGFPG LQGPAGLPGA PGISLPSLIA GQPGDPGRPG LDGERGRPGP AGPPGPPGPS 
    SNQGDTGDPG FPGIPGPKGP KGDQGIPGFS GLPGELGLKG SSGLQGDPGQ TPTAEAVQVP 
    PGPLGLPGID GIPGLTGDPG AQGPVGLQGS KGLPGIPGKD GPSGLPGPPG ALGDPGLPGL 
    QGPPGFEGAP GQQGPFGMPG MPGQSMRVGY TLVKHSQSEQ VPPCPIGMSQ LWVGYSLLFV 
    EGQEKAHNQD LGFAGSCLPR FSTMPFIYCN INEVCHYARR NDKSYWLSTT APIPMMPVSQ 
    TQIPQYISRC SVCEAPSQAI AVHSQDITIP QCPLGWRSLW IGYSFLMHTA AGAEGGGQSL 
    VSPGSCLEDF RATPFIECSG ARGTCHYFAN KYSFWLTTVE ERQQFGELPV SETLKAGQLH 
    TRVSRCQVCM KSL

Genular Protein ID: 3902247062

Symbol: A8VPY0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 229
  • Mass: 25477
  • Checksum: E191D129A85D1DC3
  • Sequence:
  • SMRVGYTLVK HSQSEQAPPC PIGMSQLWVG YSLLFVEGQE KAHNQDLGFA GSCLPRFSTM 
    PFIYCNINEV CHYARRNDKS YWLSTTAPIP MMPVSQTQIP QYISRCSVCE APSQAIAVHS 
    QDITIPQCPL GWRSLWIGYS FLMHTAAGAE GGGQSLVSPG SCLEDFRATP FIECSGARGT 
    CHYFANKYSF WLTTVEERQQ FGELPVSETL KAGQLHTRVS RCQVCMKSL

Genular Protein ID: 666574101

Symbol: B7ZMM7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1666
  • Mass: 161331
  • Checksum: F7653548614EAA97
  • Sequence:
  • MHPGLWLLLV TLCLTEELAA AGEKSYGKPC GGQDCSGSCQ CFPEKGARGR PGPIGIQGPT 
    GPQGFTGSTG LSGLKGERGF PGLLGPYGPK GDKGPMGVPG FLGINGIPGH PGQPGPRGPP 
    GLDGCNGTQG AVGFPGPDGY PGLLGPPGLP GQKGSKGDPV LAPGSFKGMK GDPGLPGLDG 
    ITGPQGAPGF PGAVGPAGPP GLQGPPGPPG PLGPDGNMGL GFQGEKGVKG DVGLPGPAGP 
    PPSTGELEFM GFPKGKKGSK GEPGPKGFPG ISGPPGFPGL GTTGEKGEKG EKGIPGLPGP 
    RGPMGSEGVQ GPPGQQGKKG TLGFPGLNGF QGIEGQKGDI GLPGPDVFID IDGAVISGNP 
    GDPGVPGLPG LKGDEGIQGL RGPSGVPGLP ALSGVPGALG PQGFPGLKGD QGNPGRTTIG 
    AAGLPGRDGL PGPPGPPGPP SPEFETETLH NKEPGFPGLR GEQGPKGNLG LKGIKGDSGF 
    CACDGGVPNT GPPGEPGPPG PWGLIGLPGL KGARGDRGSG GAQGPAGAPG LVGPLGPSGP 
    KGKKGEPILS TIQGMPGDRG DSGSQGFRGV IGEPGKDGVP GLPGLPGLPG DGGQGFPGEK 
    GLPGLPGEKG HPGPPGLPGN GLPGLPGPRG LPGDKGKDGL PGQQGLPGSK GITLPCIIPG 
    SYGPSGFPGT PGFPGPKGSR GLPGTPGQPG SSGSKGEPGS PGLVHLPELP GFPGPRGEKG 
    LPGFPGLPGK DGLPGMIGSP GLPGSKGATG DIFGAENGAP GEQGLQGLTG HKGFLGDSGL 
    PGLKGVHGKP GLLGPKGERG SPGTPGQVGQ PGTPGSSGPY GIKGKSGLPG APGFPGISGH 
    PGKKGTRGKK GPPGSIVKKG LPGLKGLPGN PGLVGLKGSP GSPGVAGLPA LSGPKGEKGS 
    VGFVGFPGIP GLPGIPGTRG LKGIPGSTGK MGPSGRAGTP GEKGDRGNPG PVGIPSPRRP 
    MSNLWLKGDK GSQGSAGSNG FPGPRGDKGE AGRPGPPGLP GAPGLPGIIK GVSGKPGPPG 
    FMGIRGLPGL KGSSGITGFP GMPGESGSQG IRGSPGLPGA SGLPGLKGDN GQTVEISGSP 
    GPKGQPGESG FKGTKGRDGL IGNIGFPGNK GEDGKVGVSG DVGLPGAPGF PGVAGMRGEP 
    GLPGSSGHQG AIGPLGSPGL IGPKGPSITG VPGPAGLPGP KGEKGYPGIG IGAPGKPGLR 
    GQKGDRGFPG LQGPAGLPGA PGISLPSLIA GQPGDPGRPG LDGERGRPGP AGPPGPPGPS 
    SNQGDTGDPG FPGIPGPKGP KGDQGIPGFS GLPGELGLKG MRGEPGFMGT PGKVGPPGDP 
    GFPGMKGKAG PRGSSGLQGD PGQTPTAEAV QVPPGPLGLP GIDGIPGLTG DPGAQGPVGL 
    QGSKGLPGIP GKDGPSGLPG PPGALGDPGL PGLQGPPGFE GAPGQQGPFG MPGMPGQSMR 
    VGYTLVKHSQ SEQVSPCPIG MSQLWVGYSL LFVEGQEKAH NQDLGFAGSC LPRFSTMPFI 
    YCNINEVCHY ARRNDKSYWL STTAPIPMMP VSQTQIPQYI SRCSVCEAPS QAIAVHSQDI 
    TIPQCPLGWR SLWIGYSFLM HTAAGAEGGG QSLVSPGSCL EDFRATPFIE CSGARGTCHY 
    FANKYSFWLT TVEERQQFGE LPVSETLKAG QLHTRVSRCQ VCMKSL

Genular Protein ID: 1659076222

Symbol: B2RTX6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1633
  • Mass: 158133
  • Checksum: 31458726FAD1E11F
  • Sequence:
  • MHPGLWLLLV TLCLTEELAA AGEKSYGKPC GGQDCSGSCQ CFPEKGARGR PGPIGIQGPT 
    GPQGFTGSTG LSGLKGERGF PGLLGPYGPK GDKGPMGVPG FLGINGIPGH PGQPGPRGPP 
    GLDGCNGTQG AVGFPGPDGY PGLLGPPGLP GQKGSKGDPV LAPGSFKGMK GDPGLPGLDG 
    ITGPQGAPGF PGAVGPAGPP GLQGPPGPPG PLGPDGNMGL GFQGEKGVKG DVGLPGPAGP 
    PPSTGELEFM GFPKGKKGSK GEPGPKGFPG ISGPPGFPGL GTTGEKGEKG EKGIPGLPGP 
    RGPMGSEGVQ GPPGQQGKKG TLGFPGLNGF QGIEGQKGDI GLPGPDVFID IDGAVISGNP 
    GDPGVPGLPG LKGDEGIQGL RGPSGVPGLP ALSGVPGALG PQGFPGLKGD QGNPGRTTIG 
    AAGLPGRDGL PGPPGPPGPP SPEFETETLH NKEPGFPGLR GEQGPKGNLG LKGIKGDSGF 
    CACDGGVPNT GPPGEPGPPG PWGLIGLPGL KGARGDRGSG GAQGPAGAPG LVGPLGPSGP 
    KGKKGEPILS TIQGMPGDRG DSGSQGFRGV IGEPGKDGVP GLPGLPGLPG DGGQGFPGEK 
    GLPGLPGEKG HPGPPGLPGN GLPGLPGPRG LPGDKGKDGL PGQQGLPGSK GITLPCIIPG 
    SYGPSGFPGT PGFPGPKGSR GLPGTPGQPG SSGSKGEPGS PGLVHLPELP GFPGPRGEKG 
    LPGFPGLPGK DGLPGMIGSP GLPGSKGATG DIFGAENGAP GEQGLQGLTG HKGFLGDSGL 
    PGLKGVHGKP GLLGPKGERG SPGTPGQVGQ PGTPGSSGPY GIKGKSGLPG APGFPGISGH 
    PGKKGTRGKK GPPGSIVKKG LPGLKGLPGN PGLVGLKGSP GSPGVAGLPA LSGPKGEKGS 
    VGFVGFPGIP GLPGIPGTRG LKGIPGSTGK MGPSGRAGTP GEKGDRGNPG PVGIPSPRRP 
    MSNLWLKGDK GSQGSAGSNG FPGPRGDKGE AGRPGPPGLP GAPGLPGIIK GVSGKPGPPG 
    FMGIRGLPGL KGSSGITGFP GMPGESGSQG IRGSPGLPGA SGLPGLKGDN GQTVEISGSP 
    GPKGQPGESG FKGTKGRDGL IGNIGFPGNK GEDGKVGVSG DVGLPGAPGF PGVAGMRGEP 
    GLPGSSGHQG AIGPLGSPGL IGPKGPSITG VPGPAGLPGP KGEKGYPGIG IGAPGKPGLR 
    GQKGDRGFPG LQGPAGLPGA PGISLPSLIA GQPGDPGRPG LDGERGRPGP AGPPGPPGPS 
    SNQGDTGDPG FPGIPGPKGP KGDQGIPGFS GLPGELGLKG SSGLQGDPGQ TPTAEAVQVP 
    PGPLGLPGID GIPGLTGDPG AQGPVGLQGS KGLPGIPGKD GPSGLPGPPG ALGDPGLPGL 
    QGPPGFEGAP GQQGPFGMPG MPGQSMRVGY TLVKHSQSEQ VPPCPIGMSQ LWVGYSLLFV 
    EGQEKAHNQD LGFAGSCLPR FSTMPFIYCN INEVCHYARR NDKSYWLSTT APIPMMPVSQ 
    TQIPQYISRC SVCEAPSQAI AVHSQDITIP QCPLGWRSLW IGYSFLMHTA AGAEGGGQSL 
    VSPGSCLEDF RATPFIECSG ARGTCHYFAN KYSFWLTTVE ERQQFGELPV SETLKAGQLH 
    TRVSRCQVCM KSL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.