Genular: Defining Cellular Identity and Function

Details for: Cplx1

Gene ID: 12889

Symbol: Cplx1

Ensembl ID: ENSMUSG00000033615

Description: complexin 1

Associated with

Acetylcholine neurotransmitter release cycle
(R-MMU-264642)
Dopamine neurotransmitter release cycle
(R-MMU-212676)
Gaba synthesis, release, reuptake and degradation
(R-MMU-888590)
Glutamate neurotransmitter release cycle
(R-MMU-210500)
Neuronal system
(R-MMU-112316)
Neurotransmitter release cycle
(R-MMU-112310)
Norepinephrine neurotransmitter release cycle
(R-MMU-181430)
Serotonin neurotransmitter release cycle
(R-MMU-181429)
Transmission across chemical synapses
(R-MMU-112315)
Calyx of held
(GO:0044305)
Cell projection
(GO:0042995)
Cytoplasm
(GO:0005737)
Dendrite
(GO:0030425)
Exocytosis
(GO:0006887)
Glutamatergic synapse
(GO:0098978)
Insulin secretion
(GO:0030073)
Neuronal cell body
(GO:0043025)
Neurotransmitter transmembrane transporter activity
(GO:0005326)
Neurotransmitter transport
(GO:0006836)
Postsynapse
(GO:0098794)
Presynapse
(GO:0098793)
Protein-containing complex
(GO:0032991)
Regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane
(GO:0099145)
Regulation of neurotransmitter secretion
(GO:0046928)
Regulation of synaptic vesicle fusion to presynaptic active zone membrane
(GO:0031630)
Schaffer collateral - ca1 synapse
(GO:0098685)
Snare binding
(GO:0000149)
Snare complex
(GO:0031201)
Synapse
(GO:0045202)
Synaptic vesicle exocytosis
(GO:0016079)
Synaptobrevin 2-snap-25-syntaxin-1a-complexin i complex
(GO:0070032)
Syntaxin-1 binding
(GO:0017075)
Syntaxin binding
(GO:0019905)
Terminal bouton
(GO:0043195)

Other Information

Proteins

Complexin-1

Genular Protein ID: 3383825632

Symbol: CPLX1_MOUSE

Name: Complexin-1

UniProtKB Accession Codes:

P63040 O09057 O09142 Q3UYB3 Q64276 Q91WJ3

Database IDs:

Citations:

PubMed ID: 7635198

Title: Identification of two highly homologous presynaptic proteins distinctly localized at the dendritic and somatic synapses.

PubMed ID: 7635198

DOI: 10.1016/0014-5793(95)00713-j

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15126625

Title: Complexin I regulates glucose-induced secretion in pancreatic beta-cells.

PubMed ID: 15126625

DOI: 10.1242/jcs.01041

PubMed ID: 16000319

Title: Profound ataxia in complexin I knockout mice masks a complex phenotype that includes exploratory and habituation deficits.

PubMed ID: 16000319

DOI: 10.1093/hmg/ddi239

PubMed ID: 15911881

Title: Structurally and functionally unique complexins at retinal ribbon synapses.

PubMed ID: 15911881

DOI: 10.1083/jcb.200502115

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23345244

Title: Complexin activates exocytosis of distinct secretory vesicles controlled by different synaptotagmins.

PubMed ID: 23345244

DOI: 10.1523/jneurosci.4087-12.2013

Sequence Information:

Length: 134
Mass: 15122
Checksum: BA1B6F074923A3A4
Sequence:

MEFVMKQALG GATKDMGKML GGDEEKDPDA AKKEEERQEA LRQAEEERKA KYAKMEAERE 
VMRQGIRDKY GIKKKEEREA EAQAAMEANS EGSLTRPKKA IPPGCGDEPE EEDESILDTV 
IKYLPGPLQD MFKK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cplx1

Associated with

Other Information

Identification of two highly homologous presynaptic proteins distinctly localized at the dendritic and somatic synapses. PubMed ID: 7635198

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Complexin I regulates glucose-induced secretion in pancreatic beta-cells. PubMed ID: 15126625

Profound ataxia in complexin I knockout mice masks a complex phenotype that includes exploratory and habituation deficits. PubMed ID: 16000319

Structurally and functionally unique complexins at retinal ribbon synapses. PubMed ID: 15911881

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Complexin activates exocytosis of distinct secretory vesicles controlled by different synaptotagmins. PubMed ID: 23345244