Details for: COL5A1

Gene ID: 1289

Symbol: COL5A1

Ensembl ID: ENSG00000130635

Description: collagen type V alpha 1 chain

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 147.6741
    Cell Significance Index: -22.9700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 88.7072
    Cell Significance Index: -22.5000
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 50.8317
    Cell Significance Index: -20.9400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 46.1533
    Cell Significance Index: -21.7900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 18.7276
    Cell Significance Index: -17.8800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 18.6300
    Cell Significance Index: -22.9700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.8197
    Cell Significance Index: -22.9700
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 5.4382
    Cell Significance Index: 33.6500
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 4.2298
    Cell Significance Index: 54.1700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 3.7623
    Cell Significance Index: 78.7500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 3.6628
    Cell Significance Index: -11.2500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 2.9816
    Cell Significance Index: 46.1300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.8252
    Cell Significance Index: 55.1400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 1.4779
    Cell Significance Index: 74.6900
  • Cell Name: chondroblast (CL0000058)
    Fold Change: 1.4480
    Cell Significance Index: 8.5000
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 1.2013
    Cell Significance Index: 13.0600
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 1.1958
    Cell Significance Index: 7.5200
  • Cell Name: embryonic fibroblast (CL2000042)
    Fold Change: 1.1456
    Cell Significance Index: 5.4800
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.1441
    Cell Significance Index: 24.4600
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 0.8343
    Cell Significance Index: 4.3900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.7944
    Cell Significance Index: 17.4000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.7704
    Cell Significance Index: 105.8000
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.7228
    Cell Significance Index: 10.3800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.6168
    Cell Significance Index: 17.6800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.5721
    Cell Significance Index: 65.3000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2489
    Cell Significance Index: 49.9200
  • Cell Name: theca cell (CL0000503)
    Fold Change: 0.2468
    Cell Significance Index: 1.4500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2298
    Cell Significance Index: 29.4600
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 0.2027
    Cell Significance Index: 1.8400
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.1956
    Cell Significance Index: 1.3300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.1210
    Cell Significance Index: 2.0300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0925
    Cell Significance Index: 170.6200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0893
    Cell Significance Index: 39.4700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0518
    Cell Significance Index: 32.3300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0447
    Cell Significance Index: 84.2300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0415
    Cell Significance Index: 26.3300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0367
    Cell Significance Index: 56.5100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0338
    Cell Significance Index: 23.3800
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.0069
    Cell Significance Index: 0.0300
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 0.0067
    Cell Significance Index: 0.0700
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 0.0032
    Cell Significance Index: 0.0200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0017
    Cell Significance Index: -2.2600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0039
    Cell Significance Index: -1.3900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0063
    Cell Significance Index: -2.8700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0120
    Cell Significance Index: -0.7700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0145
    Cell Significance Index: -10.7400
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: -0.0152
    Cell Significance Index: -0.0900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0163
    Cell Significance Index: -9.2200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0262
    Cell Significance Index: -19.1900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0292
    Cell Significance Index: -22.1000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0297
    Cell Significance Index: -3.4600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0443
    Cell Significance Index: -24.1800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0519
    Cell Significance Index: -1.4500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0571
    Cell Significance Index: -0.8200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0594
    Cell Significance Index: -10.1400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0613
    Cell Significance Index: -17.6400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0619
    Cell Significance Index: -11.1600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0634
    Cell Significance Index: -12.5800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0639
    Cell Significance Index: -13.4500
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -0.0856
    Cell Significance Index: -0.8200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0914
    Cell Significance Index: -13.2800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1243
    Cell Significance Index: -15.2800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1635
    Cell Significance Index: -11.5600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1640
    Cell Significance Index: -21.1900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1785
    Cell Significance Index: -13.7000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1855
    Cell Significance Index: -18.9500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1859
    Cell Significance Index: -21.9300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1929
    Cell Significance Index: -22.1000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1985
    Cell Significance Index: -20.6700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2540
    Cell Significance Index: -20.1200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2783
    Cell Significance Index: -13.0800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2887
    Cell Significance Index: -21.5200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2951
    Cell Significance Index: -16.5600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3131
    Cell Significance Index: -21.0500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3335
    Cell Significance Index: -17.3700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3456
    Cell Significance Index: -21.2400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3465
    Cell Significance Index: -21.8400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3577
    Cell Significance Index: -15.8200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3745
    Cell Significance Index: -11.0300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3777
    Cell Significance Index: -23.1600
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.4062
    Cell Significance Index: -9.8400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4182
    Cell Significance Index: -10.7500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.4371
    Cell Significance Index: -16.5500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.4376
    Cell Significance Index: -20.4100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.4382
    Cell Significance Index: -11.7000
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.4554
    Cell Significance Index: -2.1000
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.4595
    Cell Significance Index: -7.2900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.4863
    Cell Significance Index: -25.2600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.4880
    Cell Significance Index: -22.1200
  • Cell Name: muscle fibroblast (CL1001609)
    Fold Change: -0.4889
    Cell Significance Index: -3.0000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4893
    Cell Significance Index: -25.6900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4999
    Cell Significance Index: -17.3700
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.5333
    Cell Significance Index: -11.1300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.5337
    Cell Significance Index: -14.3000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5398
    Cell Significance Index: -18.9100
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.5855
    Cell Significance Index: -8.3200
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.5988
    Cell Significance Index: -7.5400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.6083
    Cell Significance Index: -19.3800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.6104
    Cell Significance Index: -16.0500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.6155
    Cell Significance Index: -22.6000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Non-fibrillar collagen**: COL5A1 is a non-fibrillar collagen, meaning it does not form the characteristic fibrils that are characteristic of fibrillar collagens like type I and III. 2. **Heterotrimeric structure**: COL5A1 forms a heterotrimer with type III and type VIII collagen, which is essential for its function in the ECM. 3. **High expression in mesenchymal cells**: COL5A1 is highly expressed in mesenchymal cells, which are precursor cells that differentiate into various cell types, including fibroblasts, osteoblasts, and chondrocytes. 4. **Involvement in cell adhesion and migration**: COL5A1 plays a crucial role in cell adhesion and migration, which are essential processes in tissue development, wound healing, and cancer metastasis. **Pathways and Functions** COL5A1 is involved in various biological pathways, including: 1. **Assembly of collagen fibrils and other multimeric structures**: COL5A1 contributes to the formation of heterotrimeric collagen complexes, which are essential for the assembly of collagen fibrils and other multimeric structures. 2. **Axon guidance**: COL5A1 interacts with axon guidance molecules, such as Ncam1, to regulate axon guidance and neurite outgrowth. 3. **Basement membrane formation**: COL5A1 is involved in the formation of the basement membrane, a critical component of the ECM that separates epithelial cells from underlying tissues. 4. **Cell migration**: COL5A1 regulates cell migration, which is essential for tissue development, wound healing, and cancer metastasis. 5. **Collagen biosynthesis and modifying enzymes**: COL5A1 interacts with collagen biosynthetic enzymes and modifying enzymes, such as matrix metalloproteinases (MMPs), to regulate collagen biosynthesis and degradation. **Clinical Significance** Dysregulation of COL5A1 has been implicated in various diseases, including: 1. **Wound healing disorders**: COL5A1 plays a crucial role in wound healing, and its dysregulation can lead to impaired wound closure and tissue repair. 2. **Cancer metastasis**: COL5A1 is involved in the regulation of cell migration and invasion, which are critical processes in cancer metastasis. 3. **Cardiovascular disease**: COL5A1 is involved in the formation of the extracellular matrix in the heart, and its dysregulation can contribute to cardiovascular disease. 4. **Musculoskeletal disorders**: COL5A1 is involved in the regulation of collagen biosynthesis and degradation, and its dysregulation can contribute to musculoskeletal disorders, such as osteoarthritis and fibrosis. In conclusion, COL5A1 is a critical component of the extracellular matrix that plays a vital role in various biological processes, including cell adhesion, migration, and organization. Its dysregulation has been implicated in various diseases, highlighting the importance of understanding the function and regulation of COL5A1 in maintaining tissue homeostasis and preventing disease.

Genular Protein ID: 3971259662

Symbol: CO5A1_HUMAN

Name: Collagen alpha-1(V) chain

UniProtKB Accession Codes:

P20908 A0A087WXW9 Q15094 Q5SUX4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChEBI 5 ChEMBL 1 ChiTaRS 1 ComplexPortal 4 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 2 ExpressionAtlas 1 GO 26 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 5 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 12 RefSeq 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2071595

Title: Complete primary structure of human collagen alpha 1 (V) chain.

PubMed ID: 2071595

DOI: 10.1016/s0021-9258(18)98813-7

PubMed ID: 1722213

Title: The pro-alpha-1(V) collagen chain: complete primary structure, distribution of expression, and comparison with the pro-alpha-1(XI) collagen chain.

PubMed ID: 1722213

DOI: 10.1016/s0021-9258(18)54290-3

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 2496661

Title: Covalent structure of collagen: amino acid sequence of three cyanogen bromide-derived peptides from human alpha 1(V) collagen chain.

PubMed ID: 2496661

DOI: 10.1016/0003-9861(89)90262-2

PubMed ID: 2203476

Title: Primary structure of the heparin-binding site of type V collagen.

PubMed ID: 2203476

DOI: 10.1016/0304-4165(90)90108-9

PubMed ID: 1571108

Title: Isolation of the alpha 3-chain of human type V collagen and characterization by partial sequencing.

PubMed ID: 1571108

DOI: 10.1515/bchm3.1992.373.1.69

PubMed ID: 8181482

Title: Diversity in the processing events at the N-terminus of type-V collagen.

PubMed ID: 8181482

DOI: 10.1111/j.1432-1033.1994.tb18815.x

PubMed ID: 9099729

Title: The membrane-spanning proteoglycan NG2 binds to collagens V and VI through the central nonglobular domain of its core protein.

PubMed ID: 9099729

DOI: 10.1074/jbc.272.16.10769

PubMed ID: 22149965

Title: Characterization of tissue-specific and developmentally regulated alternative splicing of exon 64 in the COL5A1 gene.

PubMed ID: 22149965

DOI: 10.3109/03008207.2011.636160

PubMed ID: 9042913

Title: Mutations in the COL5A1 gene are causal in the Ehlers-Danlos syndromes I and II.

PubMed ID: 9042913

PubMed ID: 10471441

Title: Mutations in the COL5A1 coding sequence are not common in patients with spontaneous cervical artery dissections.

PubMed ID: 10471441

DOI: 10.1161/01.str.30.9.1887

PubMed ID: 10602121

Title: Compound heterozygosity for a disease-causing G1489E and disease-modifying G530S substitution in COL5A1 of a patient with the classical type of Ehlers-Danlos syndrome: an explanation of intrafamilial variability?

PubMed ID: 10602121

DOI: 10.1002/(sici)1096-8628(20000103)90:1<72::aid-ajmg13>3.0.co;2-c

PubMed ID: 11992482

Title: Homozygous Gly530Ser substitution in COL5A1 causes mild classical Ehlers-Danlos syndrome.

PubMed ID: 11992482

DOI: 10.1002/ajmg.10373

PubMed ID: 15580559

Title: The molecular basis of classic Ehlers-Danlos syndrome: a comprehensive study of biochemical and molecular findings in 48 unrelated patients.

PubMed ID: 15580559

DOI: 10.1002/humu.20107

PubMed ID: 18972565

Title: COL5A1 signal peptide mutations interfere with protein secretion and cause classic Ehlers-Danlos syndrome.

PubMed ID: 18972565

DOI: 10.1002/humu.20887

PubMed ID: 21248752

Title: Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.

PubMed ID: 21248752

DOI: 10.1038/nature09639

PubMed ID: 26477546

Title: Joubert Syndrome in French Canadians and Identification of Mutations in CEP104.

PubMed ID: 26477546

DOI: 10.1016/j.ajhg.2015.09.009

PubMed ID: 32938213

Title: A novel recurrent COL5A1 genetic variant is associated with a dysplasia-associated arterial disease exhibiting dissections and fibromuscular dysplasia.

PubMed ID: 32938213

DOI: 10.1161/atvbaha.119.313885

Sequence Information:

  • Length: 1838
  • Mass: 183560
  • Checksum: 8F18AB0B91B3A0C7
  • Sequence:
    • MDVHTRWKAR SALRPGAPLL PPLLLLLLWA PPPSRAAQPA DLLKVLDFHN LPDGITKTTG 
FCATRRSSKG PDVAYRVTKD AQLSAPTKQL YPASAFPEDF SILTTVKAKK GSQAFLVSIY 
NEQGIQQIGL ELGRSPVFLY EDHTGKPGPE DYPLFRGINL SDGKWHRIAL SVHKKNVTLI 
LDCKKKTTKF LDRSDHPMID INGIIVFGTR ILDEEVFEGD IQQLLFVSDH RAAYDYCEHY 
SPDCDTAVPD TPQSQDPNPD EYYTEGDGEG ETYYYEYPYY EDPEDLGKEP TPSKKPVEAA 
KETTEVPEEL TPTPTEAAPM PETSEGAGKE EDVGIGDYDY VPSEDYYTPS PYDDLTYGEG 
EENPDQPTDP GAGAEIPTST ADTSNSSNPA PPPGEGADDL EGEFTEETIR NLDENYYDPY 
YDPTSSPSEI GPGMPANQDT IYEGIGGPRG EKGQKGEPAI IEPGMLIEGP PGPEGPAGLP 
GPPGTMGPTG QVGDPGERGP PGRPGLPGAD GLPGPPGTML MLPFRFGGGG DAGSKGPMVS 
AQESQAQAIL QQARLALRGP AGPMGLTGRP GPVGPPGSGG LKGEPGDVGP QGPRGVQGPP 
GPAGKPGRRG RAGSDGARGM PGQTGPKGDR GFDGLAGLPG EKGHRGDPGP SGPPGPPGDD 
GERGDDGEVG PRGLPGEPGP RGLLGPKGPP GPPGPPGVTG MDGQPGPKGN VGPQGEPGPP 
GQQGNPGAQG LPGPQGAIGP PGEKGPLGKP GLPGMPGADG PPGHPGKEGP PGEKGGQGPP 
GPQGPIGYPG PRGVKGADGI RGLKGTKGEK GEDGFPGFKG DMGIKGDRGE IGPPGPRGED 
GPEGPKGRGG PNGDPGPLGP PGEKGKLGVP GLPGYPGRQG PKGSIGFPGF PGANGEKGGR 
GTPGKPGPRG QRGPTGPRGE RGPRGITGKP GPKGNSGGDG PAGPPGERGP NGPQGPTGFP 
GPKGPPGPPG KDGLPGHPGQ RGETGFQGKT GPPGPPGVVG PQGPTGETGP MGERGHPGPP 
GPPGEQGLPG LAGKEGTKGD PGPAGLPGKD GPPGLRGFPG DRGLPGPVGA LGLKGNEGPP 
GPPGPAGSPG ERGPAGAAGP IGIPGRPGPQ GPPGPAGEKG APGEKGPQGP AGRDGLQGPV 
GLPGPAGPVG PPGEDGDKGE IGEPGQKGSK GDKGEQGPPG PTGPQGPIGQ PGPSGADGEP 
GPRGQQGLFG QKGDEGPRGF PGPPGPVGLQ GLPGPPGEKG ETGDVGQMGP PGPPGPRGPS 
GAPGADGPQG PPGGIGNPGA VGEKGEPGEA GEPGLPGEGG PPGPKGERGE KGESGPSGAA 
GPPGPKGPPG DDGPKGSPGP VGFPGDPGPP GEPGPAGQDG PPGDKGDDGE PGQTGSPGPT 
GEPGPSGPPG KRGPPGPAGP EGRQGEKGAK GEAGLEGPPG KTGPIGPQGA PGKPGPDGLR 
GIPGPVGEQG LPGSPGPDGP PGPMGPPGLP GLKGDSGPKG EKGHPGLIGL IGPPGEQGEK 
GDRGLPGPQG SSGPKGEQGI TGPSGPIGPP GPPGLPGPPG PKGAKGSSGP TGPKGEAGHP 
GPPGPPGPPG EVIQPLPIQA SRTRRNIDAS QLLDDGNGEN YVDYADGMEE IFGSLNSLKL 
EIEQMKRPLG TQQNPARTCK DLQLCHPDFP DGEYWVDPNQ GCSRDSFKVY CNFTAGGSTC 
VFPDKKSEGA RITSWPKENP GSWFSEFKRG KLLSYVDAEG NPVGVVQMTF LRLLSASAHQ 
NVTYHCYQSV AWQDAATGSY DKALRFLGSN DEEMSYDNNP YIRALVDGCA TKKGYQKTVL 
EIDTPKVEQV PIVDIMFNDF GEASQKFGFE VGPACFMG

Genular Protein ID: 3159232055

Symbol: B2ZZ86_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2ZZ86

Database IDs:

ARBA 4 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 2 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 RefSeq 2 SAM 2 SMART 3 SMR 1 SUPFAM 1

Citations:

PubMed ID: 18487259

Title: Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method.

PubMed ID: 18487259

DOI: 10.1093/dnares/dsn010

Sequence Information:

  • Length: 1838
  • Mass: 183590
  • Checksum: 89555ECC95357057
  • Sequence:
    • MDVHTRWKAR SALRPGAPLL PPLLLLLLWA PPPSRAAQPA DLLKVLDFHN LPDGITKTTG 
FCATRRSSKG PDVAYRVTKD AQLSAPTKQL YPASAFPEDF SILTTVKAKK GSQAFLVSIY 
NEQGIQQIGL ELGRSPVFLY EDHTGKPGPE DYPLFRGINL SDGKWHRIAL SVHKKNVTLI 
LDCKKKTTKF LDRSDHPMID INGIIVFGTR ILDEEVFEGD IQQLLFVSDH RAAYDYCEHY 
SPDCDTAVPD TPQSQDPNPD EYYTEGDGEG ETYYYEYPYY EDPEDLGKEP TPSKKPVEAA 
KETTEVPEEL TPTPTEAAPM PETSEGAGKE EDVGIGDYDY VPSEDYYTPS PYDDLTYGEG 
EENPDQPTDP GAGAEIPTST ADTSNSSNPA PPPGEGADDL EGEFTEETIR NLDENYYDPY 
YDPTSSPSEI GPGMPANQDT IYEGIGGPRG EKGQKGEPAI IEPGMLIEGP PGPEGPAGLP 
GPPGTMGPTG QVGDPGERGP PGRPGLPGAD GLPGPPGTML MLPFRFGGGS DAGSKGPMVS 
AQESQAQAIL QQARLALRGP AGPMGLTGRP GPVGPPGSGG LKGEPGDVGP QGPRGVQGPP 
GPAGKPGRRG RAGSDGARGM PGQTGPKGDR GFDGLAGLPG EKGHRGDPGP SGPPGPPGDD 
GERGDDGEVG PRGLPGEPGP RGLLGPKGPP GPPGPPGVTG MDGQPGPKGN VGPQGEPGPP 
GQQGNPGAQG LPGPQGAIGP PGEKGPLGKP GLPGMPGADG PPGHPGKEGP PGEKGGQGPP 
GPQGPIGYPG PRGVKGADGI RGLKGTKGEK GEDGFPGFKG DMGIKGDRGE IGPPGPRGED 
GPEGPKGRGG PNGDPGPLGP PGEKGKLGVP GLPGYPGRQG PKGSIGFPGF PGANGEKGGR 
GTPGKPGPRG QRGPTGPRGE RGPRGITGKP GPKGNSGGDG PAGPPGERGP NGPQGPTGFP 
GPKGPPGPPG KDGLPGHPGQ RGETGFQGKT GPPGPPGVVG PQGPTGETGP MGERGHPGPP 
GPPGEQGLPG LAGKEGTKGD PGPAGLPGKD GPPGLRGFPG DRGLPGPVGA LGLKGNEGPP 
GPPGPAGSPG ERGPAGAAGP IGIPGRPGPQ GPPGPAGEKG APGEKGPQGP AGRDGLQGPV 
GLPGPAGPVG PPGEDGDKGE IGEPGQKGSK GDKGEQGPPG PTGPQGPIGQ PGPSGADGEP 
GPRGQQGLFG QKGDEGPRGF PGPPGPVGLQ GLPGPPGEKG ETGDVGQMGP PGPPGPRGPS 
GAPGADGPQG PPGGIGNPGA VGEKGEPGEA GEPGLPGEGG PPGPKGERGE KGESGPSGAA 
GPPGPKGPPG DDGPKGSPGP VGFPGDPGPP GEPGPAGQDG PPGDKGDDGE PGQTGSPGPT 
GEPGPSGPPG KRGPPGPAGP EGRQGEKGAK GEAGLEGPPG KTGPIGPQGA PGKPGPDGLR 
GIPGPVGEQG LPGSPGPDGP PGPMGPPGLP GLKGDSGPKG EKGHPGLIGL IGPPGEQGEK 
GDRGLPGPQG SSGPKGEQGI TGPSGPIGPP GPPGLPGPPG PKGAKGSSGP TGPKGEAGHP 
GPPGPPGPPG EVIQPLPIQA SRTRRNIDAS QLLDDGNGEN YVDYADGMEE IFGSLNSLKL 
EIEQMKRPLG TQQNPARTCK DLQLCHPDFP DGEYWVDPNQ GCSRDSFKVY CNFTAGGSTC 
VFPDKKSEGA RITSWPKENP GSWFSEFKRG KLLSYVDAEG NPVGVVQMTF LRLLSASAHQ 
NVTYHCYQSV AWQDAATGSY DKALRFLGSN DEEMSYDNNP YIRALVDGCA TKKGYQKTVL 
EIDTPKVEQV PIVDIMFNDF GEASQKFGFE VGPACFMG

Genular Protein ID: 1410824138

Symbol: Q59EE7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59EE7

Database IDs:

ARBA 4 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 2 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 2 SAM 1 SMART 3 SMR 1 SUPFAM 1

Sequence Information:

  • Length: 1792
  • Mass: 178517
  • Checksum: E47B3093C34C5A9D
  • Sequence:
    • DFHNLPDGIT KTTGFCATRR SSKGPDVAYR VTKDAQLSAP TKQLYPASAF PEDFSILTTV 
KAKKGSQAFL VSIYNEQGIQ QIGLELGRSP VFLYEDHTGK PGPEDYPLFR GINLSDGKWH 
RIALSVHKKN VTLILDCKKK TTKFLDRSDH PMIDINGIIV FGTRILDEEV FEGDIQQLLF 
VSDHRAAYDY CEHYSPDCDT AVPDTPQSQD PNPDEYYTEG DGEGETYYYE YPYYEDPEDL 
GKEPTPSKKP VEAAKETTEV PEELTPTPTE AAPMPETSEG AGKEEDVGIG DYDYVPSEDY 
YTPSPYDDLT YGEGEENPDQ PTDPGAGAEI PTSTADTSNS SNPAPPPGEG ADDLEGEFTE 
ETIRNLDENY YDPYYDPTSS PSEIGPGMPA NQDTIYEGIG GPRGEKGQKG EPAIIEPGML 
IEGPPGPEGP AGLPGPPGTM GPTGQVGDPG ERGPPGRPGL PGADGLPGPP GTMLMLPFRF 
GGGGDAGSKG PMVSAQESQA QAILQQARLA LRGPAGPMGL TGRPGPVGPP GSGGLKGEPG 
DVGPQGPRGV QGPPGPAGKP GRRGRAGSDG ARGMPGQTGP KGDRGFDGLA GLPGEKGHRG 
DPGPSGPPGP PGDDGERGDD GEVGPRGLPG EPGPRGLLGP KGPPGPPGPP GVTGMDGQPG 
PKGNVGPQGE PGPPGQQGNP GAQGLPGPQG AIGPPGEKGP LGKPGLPGMP GADGPPGHPG 
KEGPPGEKGG QGPPGPQGPI GYPGPRGVKG ADGIRGLKGT KGEKGEDGFP GFKGDMGIKG 
DRGEIGPPGP RGEDGPEGPK GRGGPNGDPG PLGPPGEKGK LGVPGLPGYP GRQGPKGSIG 
FPGFPGANGE KGGRGTPGKP GPRGQRGPTG PRGERGPRGI TGKPGPKGNS GGDGPAGPPG 
ERGPNGPQGP TGFPGPKGPP GPPGKDGLPG HPGQRGETGF QGKTGPPGPP GVVGPQGPTG 
ETGPMGERGH PGPPGPPGEQ GLPGLAGKEG TKGDPGPAGL PGKDGPPGLR GFPGDRGLPG 
PVGALGLKGN EGPPGPPGPA GSPGERGPAG AAGPIGIPGR PGPQGPPGPA GEKGAPGEKG 
PQGPAGRDGL QGPVGLPGPA GPVGPPGEDG DKGEIGEPGQ KGSKGDKGEQ GPPGPTGPQG 
PIGQPGPSGA DGEPGPRGQQ GLFGQKGDEG PRGFPGPPGP VGLQGLPGPP GEKGETGDVG 
QMGPPGPPGP RGPSGAPGAD GPQGPPGGIG NPGAVGEKGE PGEAGEPGLP GEGGPPGPKG 
ERGEKGESGP SGAAGPPGPK GPPGDDGPKG SPGPVGFPGD PGPPGEPGPA GQDGPPGDKG 
DDGEPGQTGS PGPTGEPGPS GPPGKRGPPG PAGPEGRQGE KGAKGEAGLE GPPGKTGPIG 
PQGAPGKPGP DGLRGIPGPV GEQGLPGSPG PDGPPGPMGP PGLPGLKGDS GPKGEKGHPG 
LIGLIGPPGE QGEKGDRGLP GPQGSSGPKG EQGITGPSGP IGPPGPPGLP GPPGPKGAKG 
SSGPTGPKGE AGHPGPPGPP GPPGEVIQPL PIQASRTRRN IDASQLLDDG NGENYVDYAD 
GMEEIFGSLN SLKLEIEQMK RPLGTQQNPA RTCKDLQLCH PDFPDGEYWV DPNQGCSRDS 
FKVYCNFTAG GSTCVFPDKK SEGARITSWP KENPGSWFSE FKRGKLLSYV DAEGNPVGVV 
QMTFLRLLSA SAHQNVTYHC YQSVAWQDAA TGSYDKALRF LGSNDEEMSY DNNPYIRALV 
DGCATKKGYQ KTVLEIDTPK VEQVPIVDIM FNDFGEASQK FGFEVGPACF MG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.