Details for: COL5A1

Gene ID: 1289

Symbol: COL5A1

Ensembl ID: ENSG00000130635

Description: collagen type V alpha 1 chain

Associated with

Other Information

Genular Protein ID: 3971259662

Symbol: CO5A1_HUMAN

Name: Collagen alpha-1(V) chain

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2071595

Title: Complete primary structure of human collagen alpha 1 (V) chain.

PubMed ID: 2071595

DOI: 10.1016/s0021-9258(18)98813-7

PubMed ID: 1722213

Title: The pro-alpha-1(V) collagen chain: complete primary structure, distribution of expression, and comparison with the pro-alpha-1(XI) collagen chain.

PubMed ID: 1722213

DOI: 10.1016/s0021-9258(18)54290-3

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 2496661

Title: Covalent structure of collagen: amino acid sequence of three cyanogen bromide-derived peptides from human alpha 1(V) collagen chain.

PubMed ID: 2496661

DOI: 10.1016/0003-9861(89)90262-2

PubMed ID: 2203476

Title: Primary structure of the heparin-binding site of type V collagen.

PubMed ID: 2203476

DOI: 10.1016/0304-4165(90)90108-9

PubMed ID: 1571108

Title: Isolation of the alpha 3-chain of human type V collagen and characterization by partial sequencing.

PubMed ID: 1571108

DOI: 10.1515/bchm3.1992.373.1.69

PubMed ID: 8181482

Title: Diversity in the processing events at the N-terminus of type-V collagen.

PubMed ID: 8181482

DOI: 10.1111/j.1432-1033.1994.tb18815.x

PubMed ID: 9099729

Title: The membrane-spanning proteoglycan NG2 binds to collagens V and VI through the central nonglobular domain of its core protein.

PubMed ID: 9099729

DOI: 10.1074/jbc.272.16.10769

PubMed ID: 22149965

Title: Characterization of tissue-specific and developmentally regulated alternative splicing of exon 64 in the COL5A1 gene.

PubMed ID: 22149965

DOI: 10.3109/03008207.2011.636160

PubMed ID: 9042913

Title: Mutations in the COL5A1 gene are causal in the Ehlers-Danlos syndromes I and II.

PubMed ID: 9042913

PubMed ID: 10471441

Title: Mutations in the COL5A1 coding sequence are not common in patients with spontaneous cervical artery dissections.

PubMed ID: 10471441

DOI: 10.1161/01.str.30.9.1887

PubMed ID: 10602121

Title: Compound heterozygosity for a disease-causing G1489E and disease-modifying G530S substitution in COL5A1 of a patient with the classical type of Ehlers-Danlos syndrome: an explanation of intrafamilial variability?

PubMed ID: 10602121

DOI: 10.1002/(sici)1096-8628(20000103)90:1<72::aid-ajmg13>3.0.co;2-c

PubMed ID: 11992482

Title: Homozygous Gly530Ser substitution in COL5A1 causes mild classical Ehlers-Danlos syndrome.

PubMed ID: 11992482

DOI: 10.1002/ajmg.10373

PubMed ID: 15580559

Title: The molecular basis of classic Ehlers-Danlos syndrome: a comprehensive study of biochemical and molecular findings in 48 unrelated patients.

PubMed ID: 15580559

DOI: 10.1002/humu.20107

PubMed ID: 18972565

Title: COL5A1 signal peptide mutations interfere with protein secretion and cause classic Ehlers-Danlos syndrome.

PubMed ID: 18972565

DOI: 10.1002/humu.20887

PubMed ID: 21248752

Title: Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.

PubMed ID: 21248752

DOI: 10.1038/nature09639

PubMed ID: 26477546

Title: Joubert Syndrome in French Canadians and Identification of Mutations in CEP104.

PubMed ID: 26477546

DOI: 10.1016/j.ajhg.2015.09.009

PubMed ID: 32938213

Title: A novel recurrent COL5A1 genetic variant is associated with a dysplasia-associated arterial disease exhibiting dissections and fibromuscular dysplasia.

PubMed ID: 32938213

DOI: 10.1161/atvbaha.119.313885

Sequence Information:

  • Length: 1838
  • Mass: 183560
  • Checksum: 8F18AB0B91B3A0C7
  • Sequence:
  • MDVHTRWKAR SALRPGAPLL PPLLLLLLWA PPPSRAAQPA DLLKVLDFHN LPDGITKTTG 
    FCATRRSSKG PDVAYRVTKD AQLSAPTKQL YPASAFPEDF SILTTVKAKK GSQAFLVSIY 
    NEQGIQQIGL ELGRSPVFLY EDHTGKPGPE DYPLFRGINL SDGKWHRIAL SVHKKNVTLI 
    LDCKKKTTKF LDRSDHPMID INGIIVFGTR ILDEEVFEGD IQQLLFVSDH RAAYDYCEHY 
    SPDCDTAVPD TPQSQDPNPD EYYTEGDGEG ETYYYEYPYY EDPEDLGKEP TPSKKPVEAA 
    KETTEVPEEL TPTPTEAAPM PETSEGAGKE EDVGIGDYDY VPSEDYYTPS PYDDLTYGEG 
    EENPDQPTDP GAGAEIPTST ADTSNSSNPA PPPGEGADDL EGEFTEETIR NLDENYYDPY 
    YDPTSSPSEI GPGMPANQDT IYEGIGGPRG EKGQKGEPAI IEPGMLIEGP PGPEGPAGLP 
    GPPGTMGPTG QVGDPGERGP PGRPGLPGAD GLPGPPGTML MLPFRFGGGG DAGSKGPMVS 
    AQESQAQAIL QQARLALRGP AGPMGLTGRP GPVGPPGSGG LKGEPGDVGP QGPRGVQGPP 
    GPAGKPGRRG RAGSDGARGM PGQTGPKGDR GFDGLAGLPG EKGHRGDPGP SGPPGPPGDD 
    GERGDDGEVG PRGLPGEPGP RGLLGPKGPP GPPGPPGVTG MDGQPGPKGN VGPQGEPGPP 
    GQQGNPGAQG LPGPQGAIGP PGEKGPLGKP GLPGMPGADG PPGHPGKEGP PGEKGGQGPP 
    GPQGPIGYPG PRGVKGADGI RGLKGTKGEK GEDGFPGFKG DMGIKGDRGE IGPPGPRGED 
    GPEGPKGRGG PNGDPGPLGP PGEKGKLGVP GLPGYPGRQG PKGSIGFPGF PGANGEKGGR 
    GTPGKPGPRG QRGPTGPRGE RGPRGITGKP GPKGNSGGDG PAGPPGERGP NGPQGPTGFP 
    GPKGPPGPPG KDGLPGHPGQ RGETGFQGKT GPPGPPGVVG PQGPTGETGP MGERGHPGPP 
    GPPGEQGLPG LAGKEGTKGD PGPAGLPGKD GPPGLRGFPG DRGLPGPVGA LGLKGNEGPP 
    GPPGPAGSPG ERGPAGAAGP IGIPGRPGPQ GPPGPAGEKG APGEKGPQGP AGRDGLQGPV 
    GLPGPAGPVG PPGEDGDKGE IGEPGQKGSK GDKGEQGPPG PTGPQGPIGQ PGPSGADGEP 
    GPRGQQGLFG QKGDEGPRGF PGPPGPVGLQ GLPGPPGEKG ETGDVGQMGP PGPPGPRGPS 
    GAPGADGPQG PPGGIGNPGA VGEKGEPGEA GEPGLPGEGG PPGPKGERGE KGESGPSGAA 
    GPPGPKGPPG DDGPKGSPGP VGFPGDPGPP GEPGPAGQDG PPGDKGDDGE PGQTGSPGPT 
    GEPGPSGPPG KRGPPGPAGP EGRQGEKGAK GEAGLEGPPG KTGPIGPQGA PGKPGPDGLR 
    GIPGPVGEQG LPGSPGPDGP PGPMGPPGLP GLKGDSGPKG EKGHPGLIGL IGPPGEQGEK 
    GDRGLPGPQG SSGPKGEQGI TGPSGPIGPP GPPGLPGPPG PKGAKGSSGP TGPKGEAGHP 
    GPPGPPGPPG EVIQPLPIQA SRTRRNIDAS QLLDDGNGEN YVDYADGMEE IFGSLNSLKL 
    EIEQMKRPLG TQQNPARTCK DLQLCHPDFP DGEYWVDPNQ GCSRDSFKVY CNFTAGGSTC 
    VFPDKKSEGA RITSWPKENP GSWFSEFKRG KLLSYVDAEG NPVGVVQMTF LRLLSASAHQ 
    NVTYHCYQSV AWQDAATGSY DKALRFLGSN DEEMSYDNNP YIRALVDGCA TKKGYQKTVL 
    EIDTPKVEQV PIVDIMFNDF GEASQKFGFE VGPACFMG

Genular Protein ID: 3159232055

Symbol: B2ZZ86_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 18487259

Title: Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method.

PubMed ID: 18487259

DOI: 10.1093/dnares/dsn010

Sequence Information:

  • Length: 1838
  • Mass: 183590
  • Checksum: 89555ECC95357057
  • Sequence:
  • MDVHTRWKAR SALRPGAPLL PPLLLLLLWA PPPSRAAQPA DLLKVLDFHN LPDGITKTTG 
    FCATRRSSKG PDVAYRVTKD AQLSAPTKQL YPASAFPEDF SILTTVKAKK GSQAFLVSIY 
    NEQGIQQIGL ELGRSPVFLY EDHTGKPGPE DYPLFRGINL SDGKWHRIAL SVHKKNVTLI 
    LDCKKKTTKF LDRSDHPMID INGIIVFGTR ILDEEVFEGD IQQLLFVSDH RAAYDYCEHY 
    SPDCDTAVPD TPQSQDPNPD EYYTEGDGEG ETYYYEYPYY EDPEDLGKEP TPSKKPVEAA 
    KETTEVPEEL TPTPTEAAPM PETSEGAGKE EDVGIGDYDY VPSEDYYTPS PYDDLTYGEG 
    EENPDQPTDP GAGAEIPTST ADTSNSSNPA PPPGEGADDL EGEFTEETIR NLDENYYDPY 
    YDPTSSPSEI GPGMPANQDT IYEGIGGPRG EKGQKGEPAI IEPGMLIEGP PGPEGPAGLP 
    GPPGTMGPTG QVGDPGERGP PGRPGLPGAD GLPGPPGTML MLPFRFGGGS DAGSKGPMVS 
    AQESQAQAIL QQARLALRGP AGPMGLTGRP GPVGPPGSGG LKGEPGDVGP QGPRGVQGPP 
    GPAGKPGRRG RAGSDGARGM PGQTGPKGDR GFDGLAGLPG EKGHRGDPGP SGPPGPPGDD 
    GERGDDGEVG PRGLPGEPGP RGLLGPKGPP GPPGPPGVTG MDGQPGPKGN VGPQGEPGPP 
    GQQGNPGAQG LPGPQGAIGP PGEKGPLGKP GLPGMPGADG PPGHPGKEGP PGEKGGQGPP 
    GPQGPIGYPG PRGVKGADGI RGLKGTKGEK GEDGFPGFKG DMGIKGDRGE IGPPGPRGED 
    GPEGPKGRGG PNGDPGPLGP PGEKGKLGVP GLPGYPGRQG PKGSIGFPGF PGANGEKGGR 
    GTPGKPGPRG QRGPTGPRGE RGPRGITGKP GPKGNSGGDG PAGPPGERGP NGPQGPTGFP 
    GPKGPPGPPG KDGLPGHPGQ RGETGFQGKT GPPGPPGVVG PQGPTGETGP MGERGHPGPP 
    GPPGEQGLPG LAGKEGTKGD PGPAGLPGKD GPPGLRGFPG DRGLPGPVGA LGLKGNEGPP 
    GPPGPAGSPG ERGPAGAAGP IGIPGRPGPQ GPPGPAGEKG APGEKGPQGP AGRDGLQGPV 
    GLPGPAGPVG PPGEDGDKGE IGEPGQKGSK GDKGEQGPPG PTGPQGPIGQ PGPSGADGEP 
    GPRGQQGLFG QKGDEGPRGF PGPPGPVGLQ GLPGPPGEKG ETGDVGQMGP PGPPGPRGPS 
    GAPGADGPQG PPGGIGNPGA VGEKGEPGEA GEPGLPGEGG PPGPKGERGE KGESGPSGAA 
    GPPGPKGPPG DDGPKGSPGP VGFPGDPGPP GEPGPAGQDG PPGDKGDDGE PGQTGSPGPT 
    GEPGPSGPPG KRGPPGPAGP EGRQGEKGAK GEAGLEGPPG KTGPIGPQGA PGKPGPDGLR 
    GIPGPVGEQG LPGSPGPDGP PGPMGPPGLP GLKGDSGPKG EKGHPGLIGL IGPPGEQGEK 
    GDRGLPGPQG SSGPKGEQGI TGPSGPIGPP GPPGLPGPPG PKGAKGSSGP TGPKGEAGHP 
    GPPGPPGPPG EVIQPLPIQA SRTRRNIDAS QLLDDGNGEN YVDYADGMEE IFGSLNSLKL 
    EIEQMKRPLG TQQNPARTCK DLQLCHPDFP DGEYWVDPNQ GCSRDSFKVY CNFTAGGSTC 
    VFPDKKSEGA RITSWPKENP GSWFSEFKRG KLLSYVDAEG NPVGVVQMTF LRLLSASAHQ 
    NVTYHCYQSV AWQDAATGSY DKALRFLGSN DEEMSYDNNP YIRALVDGCA TKKGYQKTVL 
    EIDTPKVEQV PIVDIMFNDF GEASQKFGFE VGPACFMG

Genular Protein ID: 1410824138

Symbol: Q59EE7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 1792
  • Mass: 178517
  • Checksum: E47B3093C34C5A9D
  • Sequence:
  • DFHNLPDGIT KTTGFCATRR SSKGPDVAYR VTKDAQLSAP TKQLYPASAF PEDFSILTTV 
    KAKKGSQAFL VSIYNEQGIQ QIGLELGRSP VFLYEDHTGK PGPEDYPLFR GINLSDGKWH 
    RIALSVHKKN VTLILDCKKK TTKFLDRSDH PMIDINGIIV FGTRILDEEV FEGDIQQLLF 
    VSDHRAAYDY CEHYSPDCDT AVPDTPQSQD PNPDEYYTEG DGEGETYYYE YPYYEDPEDL 
    GKEPTPSKKP VEAAKETTEV PEELTPTPTE AAPMPETSEG AGKEEDVGIG DYDYVPSEDY 
    YTPSPYDDLT YGEGEENPDQ PTDPGAGAEI PTSTADTSNS SNPAPPPGEG ADDLEGEFTE 
    ETIRNLDENY YDPYYDPTSS PSEIGPGMPA NQDTIYEGIG GPRGEKGQKG EPAIIEPGML 
    IEGPPGPEGP AGLPGPPGTM GPTGQVGDPG ERGPPGRPGL PGADGLPGPP GTMLMLPFRF 
    GGGGDAGSKG PMVSAQESQA QAILQQARLA LRGPAGPMGL TGRPGPVGPP GSGGLKGEPG 
    DVGPQGPRGV QGPPGPAGKP GRRGRAGSDG ARGMPGQTGP KGDRGFDGLA GLPGEKGHRG 
    DPGPSGPPGP PGDDGERGDD GEVGPRGLPG EPGPRGLLGP KGPPGPPGPP GVTGMDGQPG 
    PKGNVGPQGE PGPPGQQGNP GAQGLPGPQG AIGPPGEKGP LGKPGLPGMP GADGPPGHPG 
    KEGPPGEKGG QGPPGPQGPI GYPGPRGVKG ADGIRGLKGT KGEKGEDGFP GFKGDMGIKG 
    DRGEIGPPGP RGEDGPEGPK GRGGPNGDPG PLGPPGEKGK LGVPGLPGYP GRQGPKGSIG 
    FPGFPGANGE KGGRGTPGKP GPRGQRGPTG PRGERGPRGI TGKPGPKGNS GGDGPAGPPG 
    ERGPNGPQGP TGFPGPKGPP GPPGKDGLPG HPGQRGETGF QGKTGPPGPP GVVGPQGPTG 
    ETGPMGERGH PGPPGPPGEQ GLPGLAGKEG TKGDPGPAGL PGKDGPPGLR GFPGDRGLPG 
    PVGALGLKGN EGPPGPPGPA GSPGERGPAG AAGPIGIPGR PGPQGPPGPA GEKGAPGEKG 
    PQGPAGRDGL QGPVGLPGPA GPVGPPGEDG DKGEIGEPGQ KGSKGDKGEQ GPPGPTGPQG 
    PIGQPGPSGA DGEPGPRGQQ GLFGQKGDEG PRGFPGPPGP VGLQGLPGPP GEKGETGDVG 
    QMGPPGPPGP RGPSGAPGAD GPQGPPGGIG NPGAVGEKGE PGEAGEPGLP GEGGPPGPKG 
    ERGEKGESGP SGAAGPPGPK GPPGDDGPKG SPGPVGFPGD PGPPGEPGPA GQDGPPGDKG 
    DDGEPGQTGS PGPTGEPGPS GPPGKRGPPG PAGPEGRQGE KGAKGEAGLE GPPGKTGPIG 
    PQGAPGKPGP DGLRGIPGPV GEQGLPGSPG PDGPPGPMGP PGLPGLKGDS GPKGEKGHPG 
    LIGLIGPPGE QGEKGDRGLP GPQGSSGPKG EQGITGPSGP IGPPGPPGLP GPPGPKGAKG 
    SSGPTGPKGE AGHPGPPGPP GPPGEVIQPL PIQASRTRRN IDASQLLDDG NGENYVDYAD 
    GMEEIFGSLN SLKLEIEQMK RPLGTQQNPA RTCKDLQLCH PDFPDGEYWV DPNQGCSRDS 
    FKVYCNFTAG GSTCVFPDKK SEGARITSWP KENPGSWFSE FKRGKLLSYV DAEGNPVGVV 
    QMTFLRLLSA SAHQNVTYHC YQSVAWQDAA TGSYDKALRF LGSNDEEMSY DNNPYIRALV 
    DGCATKKGYQ KTVLEIDTPK VEQVPIVDIM FNDFGEASQK FGFEVGPACF MG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.