Details for: COL5A1

Gene ID: 1289

Symbol: COL5A1

Ensembl ID: ENSG00000130635

Description: collagen type V alpha 1 chain

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 3.56
    Marker Score: 4895
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 3.01
    Marker Score: 1676
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 2.47
    Marker Score: 32609
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 2.44
    Marker Score: 1380
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 2.25
    Marker Score: 637
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 2.25
    Marker Score: 3457
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.11
    Marker Score: 23736
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.98
    Marker Score: 12912
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.82
    Marker Score: 3504.5
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 1.79
    Marker Score: 1197
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.7
    Marker Score: 2113
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 1.66
    Marker Score: 4354
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.43
    Marker Score: 1926
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 1.41
    Marker Score: 892.5
  • Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
    Fold Change: 1.36
    Marker Score: 305
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.32
    Marker Score: 2691
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.31
    Marker Score: 341
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 1.28
    Marker Score: 3007.5
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.24
    Marker Score: 5146
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.21
    Marker Score: 18936
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 1.2
    Marker Score: 386
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.12
    Marker Score: 4845
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.12
    Marker Score: 37799
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 1.1
    Marker Score: 6631
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 1.06
    Marker Score: 810
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 1.04
    Marker Score: 382
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.04
    Marker Score: 251784
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 1.03
    Marker Score: 992
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.02
    Marker Score: 572
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 1
    Marker Score: 1239
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71803
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48026
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30406
  • Cell Name: smooth muscle cell of large intestine (CL1000279)
    Fold Change: 0.97
    Marker Score: 368
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2413
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 0.92
    Marker Score: 228
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.92
    Marker Score: 437
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 0.92
    Marker Score: 862
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2734
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.9
    Marker Score: 5129
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.89
    Marker Score: 537
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 0.87
    Marker Score: 1006
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.87
    Marker Score: 201
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.87
    Marker Score: 29659.5
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5278
  • Cell Name: interstitial cell of Cajal (CL0002088)
    Fold Change: 0.87
    Marker Score: 301
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: 0.85
    Marker Score: 1105
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 0.83
    Marker Score: 218
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.82
    Marker Score: 258
  • Cell Name: theca cell (CL0000503)
    Fold Change: 0.81
    Marker Score: 583
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.79
    Marker Score: 388
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.78
    Marker Score: 599
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.78
    Marker Score: 2901
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1265
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.78
    Marker Score: 344
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.76
    Marker Score: 222
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.76
    Marker Score: 692
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.76
    Marker Score: 504
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.75
    Marker Score: 390
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 0.75
    Marker Score: 1406
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.75
    Marker Score: 900.5
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.73
    Marker Score: 3070
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 0.73
    Marker Score: 254
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 0.73
    Marker Score: 781
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.72
    Marker Score: 272
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.71
    Marker Score: 865
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 0.71
    Marker Score: 680
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 0.71
    Marker Score: 223.5
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.69
    Marker Score: 458
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.69
    Marker Score: 1629
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.69
    Marker Score: 335
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.68
    Marker Score: 175
  • Cell Name: muscle precursor cell (CL0000680)
    Fold Change: 0.68
    Marker Score: 175
  • Cell Name: Unknown (CL0002371)
    Fold Change: 0.67
    Marker Score: 715.5
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 0.66
    Marker Score: 563
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.65
    Marker Score: 704
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.64
    Marker Score: 424
  • Cell Name: osteoblast (CL0000062)
    Fold Change: 0.63
    Marker Score: 336
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.62
    Marker Score: 745
  • Cell Name: cardiac mesenchymal cell (CL0000569)
    Fold Change: 0.61
    Marker Score: 151
  • Cell Name: memory T cell (CL0000813)
    Fold Change: 0.61
    Marker Score: 263
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 0.61
    Marker Score: 328
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.6
    Marker Score: 502
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 0.6
    Marker Score: 249
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 0.59
    Marker Score: 143
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.59
    Marker Score: 189
  • Cell Name: meningeal macrophage (CL0000879)
    Fold Change: 0.58
    Marker Score: 162
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 0.57
    Marker Score: 2379
  • Cell Name: mesenchymal lymphangioblast (CL0005021)
    Fold Change: 0.57
    Marker Score: 127
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.57
    Marker Score: 9124
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.56
    Marker Score: 444
  • Cell Name: pericyte (CL0000669)
    Fold Change: 0.55
    Marker Score: 322
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.55
    Marker Score: 589
  • Cell Name: reticular cell (CL0000432)
    Fold Change: 0.54
    Marker Score: 197
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.54
    Marker Score: 137
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.53
    Marker Score: 264
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.52
    Marker Score: 1144
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.52
    Marker Score: 134
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 0.51
    Marker Score: 550
  • Cell Name: chondrocyte (CL0000138)
    Fold Change: 0.51
    Marker Score: 230

Hover over a box to see details here...

Hover over a box to see details here...

Hover over a box to see details here...

Other Information

**Key characteristics:** - COL5A1 is a type of collagen, a large family of proteins that are involved in the structure and function of tissues. - It is a secreted protein, meaning that it is produced and released into the extracellular matrix. - It is a major component of the extracellular matrix, which is a complex network of proteins and polysaccharides that provides structural support and elasticity to tissues. **Pathways and functions:** - COL5A1 is involved in the assembly of collagen fibrils by interacting with other collagen proteins and with proteoglycans. - It is also involved in the regulation of cell migration and adhesion. - In the context of cancer, COL5A1 is often overexpressed, which can lead to the formation of tumors. **Clinical significance:** - Mutations in COL5A1 have been linked to a number of human diseases, including rheumatoid arthritis, osteoarthritis, and cancer. - Targeting COL5A1 has been investigated as a therapeutic strategy for these diseases. - A deficiency in COL5A1 has been linked to a rare genetic disorder called osteogenesis imperfecta, which is characterized by weak and brittle bones. **Additional information:** - COL5A1 is a highly conserved protein, with similar sequences found in mammals, birds, and fish. - It is a secreted protein, with a molecular weight of approximately 120 kDa. - It is a transmembrane protein, with a single transmembrane domain. - It is a member of the Collagen family of proteins, which are the most abundant proteins in the extracellular matrix.

Genular Protein ID: 3971259662

Symbol: CO5A1_HUMAN

Name: Collagen alpha-1(V) chain

UniProtKB Accession Codes:

P20908 A0A087WXW9 Q15094 Q5SUX4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChEBI 5 ChEMBL 1 ChiTaRS 1 ComplexPortal 4 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 26 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 5 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 12 RefSeq 1 SAM 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2071595

Title: Complete primary structure of human collagen alpha 1 (V) chain.

PubMed ID: 2071595

DOI: 10.1016/s0021-9258(18)98813-7

PubMed ID: 1722213

Title: The pro-alpha-1(V) collagen chain: complete primary structure, distribution of expression, and comparison with the pro-alpha-1(XI) collagen chain.

PubMed ID: 1722213

DOI: 10.1016/s0021-9258(18)54290-3

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 2496661

Title: Covalent structure of collagen: amino acid sequence of three cyanogen bromide-derived peptides from human alpha 1(V) collagen chain.

PubMed ID: 2496661

DOI: 10.1016/0003-9861(89)90262-2

PubMed ID: 2203476

Title: Primary structure of the heparin-binding site of type V collagen.

PubMed ID: 2203476

DOI: 10.1016/0304-4165(90)90108-9

PubMed ID: 1571108

Title: Isolation of the alpha 3-chain of human type V collagen and characterization by partial sequencing.

PubMed ID: 1571108

DOI: 10.1515/bchm3.1992.373.1.69

PubMed ID: 8181482

Title: Diversity in the processing events at the N-terminus of type-V collagen.

PubMed ID: 8181482

DOI: 10.1111/j.1432-1033.1994.tb18815.x

PubMed ID: 9099729

Title: The membrane-spanning proteoglycan NG2 binds to collagens V and VI through the central nonglobular domain of its core protein.

PubMed ID: 9099729

DOI: 10.1074/jbc.272.16.10769

PubMed ID: 22149965

Title: Characterization of tissue-specific and developmentally regulated alternative splicing of exon 64 in the COL5A1 gene.

PubMed ID: 22149965

DOI: 10.3109/03008207.2011.636160

PubMed ID: 9042913

Title: Mutations in the COL5A1 gene are causal in the Ehlers-Danlos syndromes I and II.

PubMed ID: 9042913

PubMed ID: 10471441

Title: Mutations in the COL5A1 coding sequence are not common in patients with spontaneous cervical artery dissections.

PubMed ID: 10471441

DOI: 10.1161/01.str.30.9.1887

PubMed ID: 10602121

Title: Compound heterozygosity for a disease-causing G1489E and disease-modifying G530S substitution in COL5A1 of a patient with the classical type of Ehlers-Danlos syndrome: an explanation of intrafamilial variability?

PubMed ID: 10602121

DOI: 10.1002/(sici)1096-8628(20000103)90:1<72::aid-ajmg13>3.0.co;2-c

PubMed ID: 11992482

Title: Homozygous Gly530Ser substitution in COL5A1 causes mild classical Ehlers-Danlos syndrome.

PubMed ID: 11992482

DOI: 10.1002/ajmg.10373

PubMed ID: 15580559

Title: The molecular basis of classic Ehlers-Danlos syndrome: a comprehensive study of biochemical and molecular findings in 48 unrelated patients.

PubMed ID: 15580559

DOI: 10.1002/humu.20107

PubMed ID: 18972565

Title: COL5A1 signal peptide mutations interfere with protein secretion and cause classic Ehlers-Danlos syndrome.

PubMed ID: 18972565

DOI: 10.1002/humu.20887

PubMed ID: 21248752

Title: Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.

PubMed ID: 21248752

DOI: 10.1038/nature09639

PubMed ID: 26477546

Title: Joubert Syndrome in French Canadians and Identification of Mutations in CEP104.

PubMed ID: 26477546

DOI: 10.1016/j.ajhg.2015.09.009

PubMed ID: 32938213

Title: A novel recurrent COL5A1 genetic variant is associated with a dysplasia-associated arterial disease exhibiting dissections and fibromuscular dysplasia.

PubMed ID: 32938213

DOI: 10.1161/atvbaha.119.313885

Sequence Information:

  • Length: 1838
  • Mass: 183560
  • Checksum: 8F18AB0B91B3A0C7
  • Sequence:
    • MDVHTRWKAR SALRPGAPLL PPLLLLLLWA PPPSRAAQPA DLLKVLDFHN LPDGITKTTG 
FCATRRSSKG PDVAYRVTKD AQLSAPTKQL YPASAFPEDF SILTTVKAKK GSQAFLVSIY 
NEQGIQQIGL ELGRSPVFLY EDHTGKPGPE DYPLFRGINL SDGKWHRIAL SVHKKNVTLI 
LDCKKKTTKF LDRSDHPMID INGIIVFGTR ILDEEVFEGD IQQLLFVSDH RAAYDYCEHY 
SPDCDTAVPD TPQSQDPNPD EYYTEGDGEG ETYYYEYPYY EDPEDLGKEP TPSKKPVEAA 
KETTEVPEEL TPTPTEAAPM PETSEGAGKE EDVGIGDYDY VPSEDYYTPS PYDDLTYGEG 
EENPDQPTDP GAGAEIPTST ADTSNSSNPA PPPGEGADDL EGEFTEETIR NLDENYYDPY 
YDPTSSPSEI GPGMPANQDT IYEGIGGPRG EKGQKGEPAI IEPGMLIEGP PGPEGPAGLP 
GPPGTMGPTG QVGDPGERGP PGRPGLPGAD GLPGPPGTML MLPFRFGGGG DAGSKGPMVS 
AQESQAQAIL QQARLALRGP AGPMGLTGRP GPVGPPGSGG LKGEPGDVGP QGPRGVQGPP 
GPAGKPGRRG RAGSDGARGM PGQTGPKGDR GFDGLAGLPG EKGHRGDPGP SGPPGPPGDD 
GERGDDGEVG PRGLPGEPGP RGLLGPKGPP GPPGPPGVTG MDGQPGPKGN VGPQGEPGPP 
GQQGNPGAQG LPGPQGAIGP PGEKGPLGKP GLPGMPGADG PPGHPGKEGP PGEKGGQGPP 
GPQGPIGYPG PRGVKGADGI RGLKGTKGEK GEDGFPGFKG DMGIKGDRGE IGPPGPRGED 
GPEGPKGRGG PNGDPGPLGP PGEKGKLGVP GLPGYPGRQG PKGSIGFPGF PGANGEKGGR 
GTPGKPGPRG QRGPTGPRGE RGPRGITGKP GPKGNSGGDG PAGPPGERGP NGPQGPTGFP 
GPKGPPGPPG KDGLPGHPGQ RGETGFQGKT GPPGPPGVVG PQGPTGETGP MGERGHPGPP 
GPPGEQGLPG LAGKEGTKGD PGPAGLPGKD GPPGLRGFPG DRGLPGPVGA LGLKGNEGPP 
GPPGPAGSPG ERGPAGAAGP IGIPGRPGPQ GPPGPAGEKG APGEKGPQGP AGRDGLQGPV 
GLPGPAGPVG PPGEDGDKGE IGEPGQKGSK GDKGEQGPPG PTGPQGPIGQ PGPSGADGEP 
GPRGQQGLFG QKGDEGPRGF PGPPGPVGLQ GLPGPPGEKG ETGDVGQMGP PGPPGPRGPS 
GAPGADGPQG PPGGIGNPGA VGEKGEPGEA GEPGLPGEGG PPGPKGERGE KGESGPSGAA 
GPPGPKGPPG DDGPKGSPGP VGFPGDPGPP GEPGPAGQDG PPGDKGDDGE PGQTGSPGPT 
GEPGPSGPPG KRGPPGPAGP EGRQGEKGAK GEAGLEGPPG KTGPIGPQGA PGKPGPDGLR 
GIPGPVGEQG LPGSPGPDGP PGPMGPPGLP GLKGDSGPKG EKGHPGLIGL IGPPGEQGEK 
GDRGLPGPQG SSGPKGEQGI TGPSGPIGPP GPPGLPGPPG PKGAKGSSGP TGPKGEAGHP 
GPPGPPGPPG EVIQPLPIQA SRTRRNIDAS QLLDDGNGEN YVDYADGMEE IFGSLNSLKL 
EIEQMKRPLG TQQNPARTCK DLQLCHPDFP DGEYWVDPNQ GCSRDSFKVY CNFTAGGSTC 
VFPDKKSEGA RITSWPKENP GSWFSEFKRG KLLSYVDAEG NPVGVVQMTF LRLLSASAHQ 
NVTYHCYQSV AWQDAATGSY DKALRFLGSN DEEMSYDNNP YIRALVDGCA TKKGYQKTVL 
EIDTPKVEQV PIVDIMFNDF GEASQKFGFE VGPACFMG

Genular Protein ID: 3159232055

Symbol: B2ZZ86_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2ZZ86

Database IDs:

ARBA 3 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 GenomeRNAi 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 RefSeq 2 SAM 2 SMART 3 SUPFAM 1

Citations:

PubMed ID: 18487259

Title: Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method.

PubMed ID: 18487259

DOI: 10.1093/dnares/dsn010

Sequence Information:

  • Length: 1838
  • Mass: 183590
  • Checksum: 89555ECC95357057
  • Sequence:
    • MDVHTRWKAR SALRPGAPLL PPLLLLLLWA PPPSRAAQPA DLLKVLDFHN LPDGITKTTG 
FCATRRSSKG PDVAYRVTKD AQLSAPTKQL YPASAFPEDF SILTTVKAKK GSQAFLVSIY 
NEQGIQQIGL ELGRSPVFLY EDHTGKPGPE DYPLFRGINL SDGKWHRIAL SVHKKNVTLI 
LDCKKKTTKF LDRSDHPMID INGIIVFGTR ILDEEVFEGD IQQLLFVSDH RAAYDYCEHY 
SPDCDTAVPD TPQSQDPNPD EYYTEGDGEG ETYYYEYPYY EDPEDLGKEP TPSKKPVEAA 
KETTEVPEEL TPTPTEAAPM PETSEGAGKE EDVGIGDYDY VPSEDYYTPS PYDDLTYGEG 
EENPDQPTDP GAGAEIPTST ADTSNSSNPA PPPGEGADDL EGEFTEETIR NLDENYYDPY 
YDPTSSPSEI GPGMPANQDT IYEGIGGPRG EKGQKGEPAI IEPGMLIEGP PGPEGPAGLP 
GPPGTMGPTG QVGDPGERGP PGRPGLPGAD GLPGPPGTML MLPFRFGGGS DAGSKGPMVS 
AQESQAQAIL QQARLALRGP AGPMGLTGRP GPVGPPGSGG LKGEPGDVGP QGPRGVQGPP 
GPAGKPGRRG RAGSDGARGM PGQTGPKGDR GFDGLAGLPG EKGHRGDPGP SGPPGPPGDD 
GERGDDGEVG PRGLPGEPGP RGLLGPKGPP GPPGPPGVTG MDGQPGPKGN VGPQGEPGPP 
GQQGNPGAQG LPGPQGAIGP PGEKGPLGKP GLPGMPGADG PPGHPGKEGP PGEKGGQGPP 
GPQGPIGYPG PRGVKGADGI RGLKGTKGEK GEDGFPGFKG DMGIKGDRGE IGPPGPRGED 
GPEGPKGRGG PNGDPGPLGP PGEKGKLGVP GLPGYPGRQG PKGSIGFPGF PGANGEKGGR 
GTPGKPGPRG QRGPTGPRGE RGPRGITGKP GPKGNSGGDG PAGPPGERGP NGPQGPTGFP 
GPKGPPGPPG KDGLPGHPGQ RGETGFQGKT GPPGPPGVVG PQGPTGETGP MGERGHPGPP 
GPPGEQGLPG LAGKEGTKGD PGPAGLPGKD GPPGLRGFPG DRGLPGPVGA LGLKGNEGPP 
GPPGPAGSPG ERGPAGAAGP IGIPGRPGPQ GPPGPAGEKG APGEKGPQGP AGRDGLQGPV 
GLPGPAGPVG PPGEDGDKGE IGEPGQKGSK GDKGEQGPPG PTGPQGPIGQ PGPSGADGEP 
GPRGQQGLFG QKGDEGPRGF PGPPGPVGLQ GLPGPPGEKG ETGDVGQMGP PGPPGPRGPS 
GAPGADGPQG PPGGIGNPGA VGEKGEPGEA GEPGLPGEGG PPGPKGERGE KGESGPSGAA 
GPPGPKGPPG DDGPKGSPGP VGFPGDPGPP GEPGPAGQDG PPGDKGDDGE PGQTGSPGPT 
GEPGPSGPPG KRGPPGPAGP EGRQGEKGAK GEAGLEGPPG KTGPIGPQGA PGKPGPDGLR 
GIPGPVGEQG LPGSPGPDGP PGPMGPPGLP GLKGDSGPKG EKGHPGLIGL IGPPGEQGEK 
GDRGLPGPQG SSGPKGEQGI TGPSGPIGPP GPPGLPGPPG PKGAKGSSGP TGPKGEAGHP 
GPPGPPGPPG EVIQPLPIQA SRTRRNIDAS QLLDDGNGEN YVDYADGMEE IFGSLNSLKL 
EIEQMKRPLG TQQNPARTCK DLQLCHPDFP DGEYWVDPNQ GCSRDSFKVY CNFTAGGSTC 
VFPDKKSEGA RITSWPKENP GSWFSEFKRG KLLSYVDAEG NPVGVVQMTF LRLLSASAHQ 
NVTYHCYQSV AWQDAATGSY DKALRFLGSN DEEMSYDNNP YIRALVDGCA TKKGYQKTVL 
EIDTPKVEQV PIVDIMFNDF GEASQKFGFE VGPACFMG

Genular Protein ID: 1410824138

Symbol: Q59EE7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59EE7

Database IDs:

ARBA 3 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 2 SAM 1 SMART 3 SUPFAM 1

Sequence Information:

  • Length: 1792
  • Mass: 178517
  • Checksum: E47B3093C34C5A9D
  • Sequence:
    • DFHNLPDGIT KTTGFCATRR SSKGPDVAYR VTKDAQLSAP TKQLYPASAF PEDFSILTTV 
KAKKGSQAFL VSIYNEQGIQ QIGLELGRSP VFLYEDHTGK PGPEDYPLFR GINLSDGKWH 
RIALSVHKKN VTLILDCKKK TTKFLDRSDH PMIDINGIIV FGTRILDEEV FEGDIQQLLF 
VSDHRAAYDY CEHYSPDCDT AVPDTPQSQD PNPDEYYTEG DGEGETYYYE YPYYEDPEDL 
GKEPTPSKKP VEAAKETTEV PEELTPTPTE AAPMPETSEG AGKEEDVGIG DYDYVPSEDY 
YTPSPYDDLT YGEGEENPDQ PTDPGAGAEI PTSTADTSNS SNPAPPPGEG ADDLEGEFTE 
ETIRNLDENY YDPYYDPTSS PSEIGPGMPA NQDTIYEGIG GPRGEKGQKG EPAIIEPGML 
IEGPPGPEGP AGLPGPPGTM GPTGQVGDPG ERGPPGRPGL PGADGLPGPP GTMLMLPFRF 
GGGGDAGSKG PMVSAQESQA QAILQQARLA LRGPAGPMGL TGRPGPVGPP GSGGLKGEPG 
DVGPQGPRGV QGPPGPAGKP GRRGRAGSDG ARGMPGQTGP KGDRGFDGLA GLPGEKGHRG 
DPGPSGPPGP PGDDGERGDD GEVGPRGLPG EPGPRGLLGP KGPPGPPGPP GVTGMDGQPG 
PKGNVGPQGE PGPPGQQGNP GAQGLPGPQG AIGPPGEKGP LGKPGLPGMP GADGPPGHPG 
KEGPPGEKGG QGPPGPQGPI GYPGPRGVKG ADGIRGLKGT KGEKGEDGFP GFKGDMGIKG 
DRGEIGPPGP RGEDGPEGPK GRGGPNGDPG PLGPPGEKGK LGVPGLPGYP GRQGPKGSIG 
FPGFPGANGE KGGRGTPGKP GPRGQRGPTG PRGERGPRGI TGKPGPKGNS GGDGPAGPPG 
ERGPNGPQGP TGFPGPKGPP GPPGKDGLPG HPGQRGETGF QGKTGPPGPP GVVGPQGPTG 
ETGPMGERGH PGPPGPPGEQ GLPGLAGKEG TKGDPGPAGL PGKDGPPGLR GFPGDRGLPG 
PVGALGLKGN EGPPGPPGPA GSPGERGPAG AAGPIGIPGR PGPQGPPGPA GEKGAPGEKG 
PQGPAGRDGL QGPVGLPGPA GPVGPPGEDG DKGEIGEPGQ KGSKGDKGEQ GPPGPTGPQG 
PIGQPGPSGA DGEPGPRGQQ GLFGQKGDEG PRGFPGPPGP VGLQGLPGPP GEKGETGDVG 
QMGPPGPPGP RGPSGAPGAD GPQGPPGGIG NPGAVGEKGE PGEAGEPGLP GEGGPPGPKG 
ERGEKGESGP SGAAGPPGPK GPPGDDGPKG SPGPVGFPGD PGPPGEPGPA GQDGPPGDKG 
DDGEPGQTGS PGPTGEPGPS GPPGKRGPPG PAGPEGRQGE KGAKGEAGLE GPPGKTGPIG 
PQGAPGKPGP DGLRGIPGPV GEQGLPGSPG PDGPPGPMGP PGLPGLKGDS GPKGEKGHPG 
LIGLIGPPGE QGEKGDRGLP GPQGSSGPKG EQGITGPSGP IGPPGPPGLP GPPGPKGAKG 
SSGPTGPKGE AGHPGPPGPP GPPGEVIQPL PIQASRTRRN IDASQLLDDG NGENYVDYAD 
GMEEIFGSLN SLKLEIEQMK RPLGTQQNPA RTCKDLQLCH PDFPDGEYWV DPNQGCSRDS 
FKVYCNFTAG GSTCVFPDKK SEGARITSWP KENPGSWFSE FKRGKLLSYV DAEGNPVGVV 
QMTFLRLLSA SAHQNVTYHC YQSVAWQDAA TGSYDKALRF LGSNDEEMSY DNNPYIRALV 
DGCATKKGYQ KTVLEIDTPK VEQVPIVDIM FNDFGEASQK FGFEVGPACF MG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.