Details for: Cplx2

Gene ID: 12890

Symbol: Cplx2

Ensembl ID: ENSMUSG00000025867

Description: complexin 2

Associated with

Other Information

Genular Protein ID: 136019840

Symbol: CPLX2_MOUSE

Name: Complexin-2

UniProtKB Accession Codes:

P84086 O09056 Q13329 Q28184 Q32KK4 Q64386

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 Ensembl 1 GO 23 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 1 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 PANTHER 2 PIR 1 PRO 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 3 SAM 1 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 7553862

Title: Complexins: cytosolic proteins that regulate SNAP receptor function.

PubMed ID: 7553862

DOI: 10.1016/0092-8674(95)90239-2

PubMed ID: 7635198

Title: Identification of two highly homologous presynaptic proteins distinctly localized at the dendritic and somatic synapses.

PubMed ID: 7635198

DOI: 10.1016/0014-5793(95)00713-j

PubMed ID: 16162394

Title: Structural organization of the human complexin 2 gene (CPLX2) and aspects of its functional activity.

PubMed ID: 16162394

DOI: 10.1016/j.gene.2005.07.005

PubMed ID: 11163241

Title: Complexins regulate a late step in Ca2+-dependent neurotransmitter release.

PubMed ID: 11163241

DOI: 10.1016/s0092-8674(01)00192-1

PubMed ID: 12915444

Title: Complexin II is essential for normal neurological function in mice.

PubMed ID: 12915444

DOI: 10.1093/hmg/ddg249

PubMed ID: 15911881

Title: Structurally and functionally unique complexins at retinal ribbon synapses.

PubMed ID: 15911881

DOI: 10.1083/jcb.200502115

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.t500041-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20346398

Title: Transcriptional inhibition of REST by NeuroD2 during neuronal differentiation.

PubMed ID: 20346398

DOI: 10.1016/j.mcn.2010.03.006

PubMed ID: 23345244

Title: Complexin activates exocytosis of distinct secretory vesicles controlled by different synaptotagmins.

PubMed ID: 23345244

DOI: 10.1523/jneurosci.4087-12.2013

Sequence Information:

  • Length: 134
  • Mass: 15394
  • Checksum: 7791812FD4194AC5
  • Sequence:
    • MDFVMKQALG GATKDMGKML GGEEEKDPDA QKKEEERQEA LRQQEEERKA KHARMEAERE 
KVRQQIRDKY GLKKKEEKEA EEKAALEQPC EGSLTRPKKA IPAGCGDEEE EEEESILDTV 
LKYLPGPLQD MFKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.