Genular: Defining Cellular Identity and Function

Details for: Crat

Gene ID: 12908

Symbol: Crat

Ensembl ID: ENSMUSG00000026853

Description: carnitine acetyltransferase

Associated with

Beta-oxidation of pristanoyl-coa
(R-MMU-389887)
Fatty acid metabolism
(R-MMU-8978868)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Peroxisomal lipid metabolism
(R-MMU-390918)
Peroxisomal protein import
(R-MMU-9033241)
Protein localization
(R-MMU-9609507)
Acyl-coa oxidase activity
(GO:0003997)
Acyltransferase activity
(GO:0016746)
Carnitine metabolic process, coa-linked
(GO:0019254)
Carnitine o-acetyltransferase activity
(GO:0004092)
Carnitine o-octanoyltransferase activity
(GO:0008458)
Endoplasmic reticulum
(GO:0005783)
Fatty acid beta-oxidation using acyl-coa oxidase
(GO:0033540)
Fatty acid metabolic process
(GO:0006631)
Lipid metabolic process
(GO:0006629)
Medium-chain fatty acid metabolic process
(GO:0051791)
Membrane
(GO:0016020)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrion
(GO:0005739)
Peroxisome
(GO:0005777)
Short-chain fatty acid metabolic process
(GO:0046459)
Transferase activity
(GO:0016740)

Other Information

Proteins

Carnitine acetyltransferase

Genular Protein ID: 1772406375

Symbol: CACP_MOUSE

Name: Carnitine acetyltransferase

UniProtKB Accession Codes:

P47934 Q3TCG3 Q3V1Y3 Q923A6

Database IDs:

Citations:

PubMed ID: 9065756

Title: Cloning and characterization of murine carnitine acetyltransferase: evidence for a requirement during cell cycle progression.

PubMed ID: 9065756

DOI: 10.1042/bj3220403

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 12526798

Title: Crystal structure of carnitine acetyltransferase and implications for the catalytic mechanism and fatty acid transport.

PubMed ID: 12526798

DOI: 10.1016/s0092-8674(02)01228-x

PubMed ID: 15155726

Title: Structural and biochemical studies of the substrate selectivity of carnitine acetyltransferase.

PubMed ID: 15155726

DOI: 10.1074/jbc.m403484200

Sequence Information:

Length: 626
Mass: 70840
Checksum: 975EA04403A4F3D9
Sequence:

MLAFAARTVV KPLGLLKPSS LMKVSGRFKA HQDALPRLPV PPLQQSLDYY LKALQPIVSE 
EEWAHTKQLV DEFQTSGGVG ERLQKGLERR AKKMENWLSE WWLKTAYLQF RQPVVIYSSP 
GVILPKQDFV DLQGQLRFAA KLIEGVLDFK SMIDNETLPV EFLGGQPLCM NQYYQILSSC 
RVPGPKQDSV VNFLKSKRPP THITVVHNYQ FFELDVYHSD GTPLTSDQIF VQLEKIWNSS 
LQSNKEPVGI LTSNHRNTWA KAYNNLIKDK VNRESVNSIQ KSIFTVCLDK QVPRVSDDVY 
RNHVAGQMLH GGGSKFNSGN RWFDKTLQFI VAEDGSCGMV YEHAAAEGPP IVALVDHVME 
YTKKPELVRS PMVPLPMPKK LRFNITPEIK NDIEKAKQNL SIMIQDLDIM MLTFHHFGKD 
FPKSEKLSPD AFIQVALQLA YYRIYGQACA TYESASLRMF HLGRTDTIRS ASIDSLAFVK 
GMGDSTVPEQ QKVELLRKAV QAHRAYTDRA IRGEAFDRHL LGLKLQAIED LVSMPDIFMD 
TSYAIAMHFN LSTSQVPAKT DCVMFFGPVV PDGYGICYNP MEAHINFSVS AYNSCAETNA 
ARMAHYLEKA LLDMRTLLQN HPRAKL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Crat

Associated with

Other Information

Cloning and characterization of murine carnitine acetyltransferase: evidence for a requirement during cell cycle progression. PubMed ID: 9065756

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Crystal structure of carnitine acetyltransferase and implications for the catalytic mechanism and fatty acid transport. PubMed ID: 12526798

Structural and biochemical studies of the substrate selectivity of carnitine acetyltransferase. PubMed ID: 15155726