Genular: Defining Cellular Identity and Function

Details for: Crh

Gene ID: 12918

Symbol: Crh

Ensembl ID: ENSMUSG00000049796

Description: corticotropin releasing hormone

Associated with

Class b/2 (secretin family receptors)
(R-MMU-373080)
G alpha (s) signalling events
(R-MMU-418555)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Signaling by gpcr
(R-MMU-372790)
Signal transduction
(R-MMU-162582)
Adrenal gland development
(GO:0030325)
Associative learning
(GO:0008306)
Cellular response to cocaine
(GO:0071314)
Corticotropin-releasing hormone activity
(GO:0017045)
Corticotropin-releasing hormone receptor 1 binding
(GO:0051430)
Corticotropin-releasing hormone receptor 2 binding
(GO:0051431)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Female pregnancy
(GO:0007565)
Glucocorticoid biosynthetic process
(GO:0006704)
Hormone-mediated apoptotic signaling pathway
(GO:0008628)
Hormone activity
(GO:0005179)
Inflammatory response
(GO:0006954)
Learning or memory
(GO:0007611)
Locomotory exploration behavior
(GO:0035641)
Long-term synaptic potentiation
(GO:0060291)
Lung development
(GO:0030324)
Negative regulation of epinephrine secretion
(GO:0032811)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of glucagon secretion
(GO:0070093)
Negative regulation of luteinizing hormone secretion
(GO:0033685)
Negative regulation of norepinephrine secretion
(GO:0010700)
Negative regulation of systemic arterial blood pressure
(GO:0003085)
Neuronal cell body
(GO:0043025)
Neuron apoptotic process
(GO:0051402)
Perikaryon
(GO:0043204)
Positive regulation of behavioral fear response
(GO:2000987)
Positive regulation of calcium ion import
(GO:0090280)
Positive regulation of camp-mediated signaling
(GO:0043950)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of corticosterone secretion
(GO:2000854)
Positive regulation of corticotropin secretion
(GO:0051461)
Positive regulation of cortisol secretion
(GO:0051464)
Positive regulation of digestive system process
(GO:0060456)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of insulin secretion involved in cellular response to glucose stimulus
(GO:0035774)
Positive regulation of protein phosphorylation
(GO:0001934)
Regulation of nmda receptor activity
(GO:2000310)
Regulation of serotonin secretion
(GO:0014062)
Synaptic transmission, dopaminergic
(GO:0001963)
Varicosity
(GO:0043196)

Other Information

Proteins

Corticoliberin

Genular Protein ID: 97569503

Symbol: CRF_MOUSE

Name: Corticoliberin

UniProtKB Accession Codes:

Q8CIT0 Q14AA2

Database IDs:

Citations:

PubMed ID: 19912808

Title: Nucleotide sequence and expression of the mouse corticotropin-releasing hormone gene.

PubMed ID: 19912808

DOI: 10.1016/1044-7431(91)90054-r

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 23470617

Title: Stress-induced corticotropin-releasing hormone-mediated NLRP6 inflammasome inhibition and transmissible enteritis in mice.

PubMed ID: 23470617

DOI: 10.1053/j.gastro.2013.02.038

Sequence Information:

Length: 187
Mass: 20778
Checksum: 5E51665291FAA998
Sequence:

MRLRLLVSAG MLLVALSSCL PCRALLSRGS VPRAPRAPQP LNFLQPEQPQ QPQPVLIRMG 
EEYFLRLGNL NRSPAARLSP NSTPLTAGRG SRPSHDQAAA NFFRVLLQQL QMPQRSLDSR 
AEPAERGAED ALGGHQGALE RERRSEEPPI SLDLTFHLLR EVLEMARAEQ LAQQAHSNRK 
LMEIIGK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.