Genular: Defining Cellular Identity and Function

Details for: Crkl

Gene ID: 12929

Symbol: Crkl

Ensembl ID: ENSMUSG00000006134

Description: v-crk avian sarcoma virus CT10 oncogene homolog-like

Associated with

Cytokine signaling in immune system
(R-MMU-1280215)
Downstream signal transduction
(R-MMU-186763)
Erythropoietin activates ras
(R-MMU-9027284)
Frs2-mediated activation
(R-MMU-170968)
Immune system
(R-MMU-168256)
Interleukin-3, interleukin-5 and gm-csf signaling
(R-MMU-512988)
Met activates rap1 and rac1
(R-MMU-8875555)
Met promotes cell motility
(R-MMU-8875878)
Met receptor recycling
(R-MMU-8875656)
Prolonged erk activation events
(R-MMU-169893)
Regulation of signaling by cbl
(R-MMU-912631)
Signaling by erythropoietin
(R-MMU-9006335)
Signaling by interleukins
(R-MMU-449147)
Signaling by met
(R-MMU-6806834)
Signaling by ntrk1 (trka)
(R-MMU-187037)
Signaling by ntrks
(R-MMU-166520)
Signaling by pdgf
(R-MMU-186797)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signalling to erks
(R-MMU-187687)
Acetylcholine receptor signaling pathway
(GO:0095500)
Activation of gtpase activity
(GO:0090630)
Animal organ morphogenesis
(GO:0009887)
Anterior/posterior pattern specification
(GO:0009952)
B cell apoptotic process
(GO:0001783)
Blood vessel development
(GO:0001568)
Cell chemotaxis
(GO:0060326)
Cell migration
(GO:0016477)
Cellular response to interleukin-7
(GO:0098761)
Cellular response to transforming growth factor beta stimulus
(GO:0071560)
Cellular response to xenobiotic stimulus
(GO:0071466)
Cerebellar neuron development
(GO:0098749)
Cerebral cortex development
(GO:0021987)
Chordate pharynx development
(GO:0160093)
Cranial skeletal system development
(GO:1904888)
Cytosol
(GO:0005829)
Dendrite development
(GO:0016358)
Endothelin receptor signaling pathway
(GO:0086100)
Enzyme-linked receptor protein signaling pathway
(GO:0007167)
Establishment of cell polarity
(GO:0030010)
Extrinsic component of postsynaptic membrane
(GO:0098890)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Heart development
(GO:0007507)
Helper t cell diapedesis
(GO:0035685)
Hippocampus development
(GO:0021766)
Identical protein binding
(GO:0042802)
Lipid metabolic process
(GO:0006629)
Male gonad development
(GO:0008584)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of protein phosphorylation
(GO:0001933)
Neuromuscular junction
(GO:0031594)
Neuron migration
(GO:0001764)
Nucleoplasm
(GO:0005654)
Outflow tract morphogenesis
(GO:0003151)
Parathyroid gland development
(GO:0060017)
Pattern specification process
(GO:0007389)
Phosphotyrosine residue binding
(GO:0001784)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of glial cell migration
(GO:1903977)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of rac protein signal transduction
(GO:0035022)
Positive regulation of skeletal muscle acetylcholine-gated channel clustering
(GO:1904395)
Positive regulation of substrate adhesion-dependent cell spreading
(GO:1900026)
Postsynaptic specialization assembly
(GO:0098698)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Receptor tyrosine kinase binding
(GO:0030971)
Reelin-mediated signaling pathway
(GO:0038026)
Regulation of cell adhesion mediated by integrin
(GO:0033628)
Regulation of cell growth
(GO:0001558)
Regulation of dendrite development
(GO:0050773)
Regulation of gene expression
(GO:0010468)
Regulation of leukocyte migration
(GO:0002685)
Regulation of skeletal muscle acetylcholine-gated channel clustering
(GO:1904393)
Regulation of t cell migration
(GO:2000404)
Response to fibroblast growth factor
(GO:0071774)
Retinoic acid receptor signaling pathway
(GO:0048384)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Signaling adaptor activity
(GO:0035591)
Signal transduction
(GO:0007165)
Single fertilization
(GO:0007338)
Spermatogenesis
(GO:0007283)
Synapse
(GO:0045202)
T cell receptor signaling pathway
(GO:0050852)
Thymus development
(GO:0048538)
Urogenital system development
(GO:0001655)

Other Information

Proteins

Crk-like protein
A0A338P6Q0_MOUSE

Genular Protein ID: 2711049614

Symbol: CRKL_MOUSE

Name: Crk-like protein

UniProtKB Accession Codes:

P47941 Q3TQ18 Q8BGC5

Database IDs:

Citations:

PubMed ID: 7478571

Title: Tyrosine phosphorylation of murine Crkl.

PubMed ID: 7478571

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 11031258

Title: SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL.

PubMed ID: 11031258

DOI: 10.1074/jbc.m006250200

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.m400085-mcp200

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 303
Mass: 33830
Checksum: A8C801F78EF73573
Sequence:

MSSARFDSSD RSAWYMGPVT RQEAQTRLQG QRHGMFLVRD SSTCPGDYVL SVSENSRVSH 
YIINSLPNRR FKIGDQEFDH LPALLEFYKI HYLDTTTLIE PAPRYPSPPV GSVSAPNLPT 
AEENLEYVRT LYDFPGNDAE DLPFKKGELL VIIEKPEEQW WSARNKDGRV GMIPVPYVEK 
LVRSSPHGKH GNRNSNSYGI PEPAHAYAQP QTTTPLPTVA STPGAAINPL PSTQNGPVFA 
KAIQKRVPCA YDKTALALEV GDIVKVTRMN INGQWEGEVN GRKGLFPFTH VKIFDPQNPD 
DNE

Genular Protein ID: 3310545551

Symbol: A0A338P6Q0_MOUSE

Name: N/A

UniProtKB Accession Codes:

A0A338P6Q0

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 108
Mass: 12435
Checksum: 2B46F4A92DB2BA3B
Sequence:

MSSARFDSSD RSAWYMGPVT RQEAQTRLQG QRHGMFLVRD SSTCPGDYVL SVSENSRVSH 
YIINSLPNRR FKIGDQEFDH LPALLEFYKI HYLDTTTLIE PAPRLVTL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Crkl

Associated with

Other Information

Tyrosine phosphorylation of murine Crkl. PubMed ID: 7478571

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL. PubMed ID: 11031258

Phosphoproteomic analysis of the developing mouse brain. PubMed ID: 15345747

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. PubMed ID: 18034455

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Database document:

PubMed ID: 7478571

PubMed ID: 16141072

PubMed ID: 11031258

PubMed ID: 15345747

PubMed ID: 18034455

PubMed ID: 21183079

PubMed ID: 19468303

PubMed ID: 21183079