Genular: Defining Cellular Identity and Function

Details for: Dpysl2

Gene ID: 12934

Symbol: Dpysl2

Ensembl ID: ENSMUSG00000022048

Description: dihydropyrimidinase-like 2

Associated with

Axon guidance
(R-MMU-422475)
Crmps in sema3a signaling
(R-MMU-399956)
Developmental biology
(R-MMU-1266738)
L1cam interactions
(R-MMU-373760)
Recycling pathway of l1
(R-MMU-437239)
Semaphorin interactions
(R-MMU-373755)
Axon
(GO:0030424)
Cell differentiation
(GO:0030154)
Cytoplasm
(GO:0005737)
Cytoskeleton
(GO:0005856)
Cytoskeleton organization
(GO:0007010)
Cytosol
(GO:0005829)
Dendrite
(GO:0030425)
Dihydropyrimidinase activity
(GO:0004157)
Endocytosis
(GO:0006897)
Growth cone
(GO:0030426)
Hydrolase activity
(GO:0016787)
Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
(GO:0016810)
Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
(GO:0016812)
Identical protein binding
(GO:0042802)
Membrane
(GO:0016020)
Microtubule
(GO:0005874)
Mitochondrion
(GO:0005739)
Multicellular organism development
(GO:0007275)
Myelin sheath
(GO:0043209)
Nervous system development
(GO:0007399)
Neuronal cell body
(GO:0043025)
Plasma membrane
(GO:0005886)
Positive regulation of glutamate secretion
(GO:0014049)
Presynapse
(GO:0098793)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)
Pyrimidine nucleobase catabolic process
(GO:0006208)
Regulation of neuron differentiation
(GO:0045664)
Regulation of neuron projection development
(GO:0010975)
Synapse
(GO:0045202)
Synaptic vesicle transport
(GO:0048489)
Terminal bouton
(GO:0043195)

Other Information

Proteins

Dihydropyrimidinase-related protein 2

Genular Protein ID: 3201787771

Symbol: DPYL2_MOUSE

Name: Dihydropyrimidinase-related protein 2

UniProtKB Accession Codes:

O08553 Q6P5D0

Database IDs:

Citations:

PubMed ID: 9652388

Title: The Ulip family phosphoproteins -- common and specific properties.

PubMed ID: 9652388

DOI: 10.1046/j.1432-1327.1998.2540014.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9375656

Title: Brain CRMP forms heterotetramers similar to liver dihydropyrimidinase.

PubMed ID: 9375656

DOI: 10.1046/j.1471-4159.1997.69062261.x

PubMed ID: 10956643

Title: Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family.

PubMed ID: 10956643

DOI: 10.1074/jbc.m003277200

PubMed ID: 15466885

Title: New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting.

PubMed ID: 15466885

DOI: 10.1242/jcs.01379

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.m400085-mcp200

PubMed ID: 15648052

Title: Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol.

PubMed ID: 15648052

DOI: 10.1002/pmic.200401066

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22057101

Title: ZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylation.

PubMed ID: 22057101

DOI: 10.1038/ncb2373

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

Sequence Information:

Length: 572
Mass: 62278
Checksum: C031F3BC038AA737
Sequence:

MSYQGKKNIP RITSDRLLIK GGKIVNDDQS FYADIYMEDG LIKQIGENLI VPGGVKTIEA 
HSRMVIPGGI DVHTRFQMPD QGMTSADDFF QGTKAALAGG TTMIIDHVVP EPGTSLLAAF 
DQWREWADSK SCCDYSLHVD ITEWHKGIQE EMEALVKDHG VNSFLVYMAF KDRFQLTDSQ 
IYEVLSVIRD IGAIAQVHAE NGDIIAEEQQ RILDLGITGP EGHVLSRPEE VEAEAVNRSI 
TIANQTNCPL YVTKVMSKSA AEVIAQARKK GTVVYGEPIT ASLGTDGSHY WSKNWAKAAA 
FVTSPPLSPD PTTPDFLNSL LSCGDLQVTG SAHCTFNTAQ KAVGKDNFTL IPEGTNGTEE 
RMSVIWDKAV VTGKMDENQF VAVTSTNAAK VFNLYPRKGR ISVGSDADLV IWDPDSVKTI 
SAKTHNSALE YNIFEGMECR GSPLVVISQG KIVLEDGTLH VTEGSGRYIP RKPFPDFVYK 
RIKARSRLAE LRGVPRGLYD GPVCEVSVTP KTVTPASSAK TSPAKQQAPP VRNLHQSGFS 
LSGAQIDDNI PRRTTQRIVA PPGGRANITS LG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Dpysl2

Associated with

Other Information

The Ulip family phosphoproteins -- common and specific properties. PubMed ID: 9652388

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Brain CRMP forms heterotetramers similar to liver dihydropyrimidinase. PubMed ID: 9375656

Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family. PubMed ID: 10956643

New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting. PubMed ID: 15466885

Phosphoproteomic analysis of the developing mouse brain. PubMed ID: 15345747

Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol. PubMed ID: 15648052

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. PubMed ID: 18034455

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry. PubMed ID: 19131326

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

ZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylation. PubMed ID: 22057101

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315