Details for: COL8A1

Gene ID: 1295

Symbol: COL8A1

Ensembl ID: ENSG00000144810

Description: collagen type VIII alpha 1 chain

Associated with

Other Information

Genular Protein ID: 197277814

Symbol: CO8A1_HUMAN

Name: Collagen alpha-1(VIII) chain

UniProtKB Accession Codes:

P27658 D3DN42 Q53XI6 Q96D07

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 ComplexPortal 2 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 EPD 1 Ensembl 3 ExpressionAtlas 1 GO 13 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 5 RefSeq 2 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2029894

Title: The complete primary structure of the human alpha 1 (VIII) chain and assignment of its gene (COL8A1) to chromosome 3.

PubMed ID: 2029894

DOI: 10.1111/j.1432-1033.1991.tb15951.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2376131

Title: Distribution of type VIII collagen in tissues: an immunohistochemical study.

PubMed ID: 2376131

DOI: 10.3109/03008209009152157

PubMed ID: 1515454

Title: Cleavage of type VIII collagen by human neutrophil elastase.

PubMed ID: 1515454

DOI: 10.1016/0925-4439(92)90103-t

PubMed ID: 7734329

Title: Human mast cells produce type VIII collagen in vivo.

PubMed ID: 7734329

PubMed ID: 10686422

Title: The alpha1(VIII) and alpha2(VIII) collagen chains form two distinct homotrimeric proteins in vivo.

PubMed ID: 10686422

DOI: 10.1016/s0945-053x(99)00053-0

PubMed ID: 11708810

Title: NC1 domain of human type VIII collagen (alpha 1) inhibits bovine aortic endothelial cell proliferation and causes cell apoptosis.

PubMed ID: 11708810

DOI: 10.1006/bbrc.2001.5970

PubMed ID: 14990571

Title: Expression and supramolecular assembly of recombinant alpha1(viii) and alpha2(viii) collagen homotrimers.

PubMed ID: 14990571

DOI: 10.1074/jbc.m305805200

PubMed ID: 17888087

Title: Collagen type VIII expression in human diabetic nephropathy.

PubMed ID: 17888087

DOI: 10.1111/j.1365-2362.2007.01864.x

Sequence Information:

  • Length: 744
  • Mass: 73364
  • Checksum: 2BC1B0955DE2C9A3
  • Sequence:
    • MAVLPGPLQL LGVLLTISLS SIRLIQAGAY YGIKPLPPQI PPQMPPQIPQ YQPLGQQVPH 
MPLAKDGLAM GKEMPHLQYG KEYPHLPQYM KEIQPAPRMG KEAVPKKGKE IPLASLRGEQ 
GPRGEPGPRG PPGPPGLPGH GIPGIKGKPG PQGYPGVGKP GMPGMPGKPG AMGMPGAKGE 
IGQKGEIGPM GIPGPQGPPG PHGLPGIGKP GGPGLPGQPG PKGDRGPKGL PGPQGLRGPK 
GDKGFGMPGA PGVKGPPGMH GPPGPVGLPG VGKPGVTGFP GPQGPLGKPG APGEPGPQGP 
IGVPGVQGPP GIPGIGKPGQ DGIPGQPGFP GGKGEQGLPG LPGPPGLPGI GKPGFPGPKG 
DRGMGGVPGA LGPRGEKGPI GAPGIGGPPG EPGLPGIPGP MGPPGAIGFP GPKGEGGIVG 
PQGPPGPKGE PGLQGFPGKP GFLGEVGPPG MRGLPGPIGP KGEAGQKGVP GLPGVPGLLG 
PKGEPGIPGD QGLQGPPGIP GIGGPSGPIG PPGIPGPKGE PGLPGPPGFP GIGKPGVAGL 
HGPPGKPGAL GPQGQPGLPG PPGPPGPPGP PAVMPPTPPP QGEYLPDMGL GIDGVKPPHA 
YGAKKGKNGG PAYEMPAFTA ELTAPFPPVG APVKFNKLLY NGRQNYNPQT GIFTCEVPGV 
YYFAYHVHCK GGNVWVALFK NNEPVMYTYD EYKKGFLDQA SGSAVLLLRP GDRVFLQMPS 
EQAAGLYAGQ YVHSSFSGYL LYPM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.