Details for: COL11A1

Gene ID: 1301

Symbol: COL11A1

Ensembl ID: ENSG00000060718

Description: collagen type XI alpha 1 chain

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 4.4382
    Cell Significance Index: 249.0500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 3.8820
    Cell Significance Index: 60.0600
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 3.6475
    Cell Significance Index: 17.7400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.6044
    Cell Significance Index: 42.9900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.8889
    Cell Significance Index: 11.0300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.7445
    Cell Significance Index: 32.9300
  • Cell Name: chondroblast (CL0000058)
    Fold Change: 0.7036
    Cell Significance Index: 4.1300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.7032
    Cell Significance Index: 14.7200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.6255
    Cell Significance Index: 432.6100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.5301
    Cell Significance Index: 106.3500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.5254
    Cell Significance Index: 11.2300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.4207
    Cell Significance Index: 28.2900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3732
    Cell Significance Index: 22.9400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.2105
    Cell Significance Index: 7.9700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1988
    Cell Significance Index: 126.2900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0927
    Cell Significance Index: 174.5000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0601
    Cell Significance Index: 21.5500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0521
    Cell Significance Index: 23.6400
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.0301
    Cell Significance Index: 0.7300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0193
    Cell Significance Index: -29.7800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0250
    Cell Significance Index: -11.0700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0319
    Cell Significance Index: -58.7700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0361
    Cell Significance Index: -49.1000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0565
    Cell Significance Index: -41.8600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0618
    Cell Significance Index: -46.7400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0768
    Cell Significance Index: -43.3000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0774
    Cell Significance Index: -48.3100
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0961
    Cell Significance Index: -1.4600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1170
    Cell Significance Index: -33.6500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1438
    Cell Significance Index: -18.4300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1489
    Cell Significance Index: -4.1600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.1736
    Cell Significance Index: -34.4600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1758
    Cell Significance Index: -25.5500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.2223
    Cell Significance Index: -40.0700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2287
    Cell Significance Index: -48.1800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.2328
    Cell Significance Index: -39.7600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2647
    Cell Significance Index: -6.9600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2935
    Cell Significance Index: -33.6300
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.3070
    Cell Significance Index: -2.0800
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.3168
    Cell Significance Index: -1.8800
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.3172
    Cell Significance Index: -7.9100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.3360
    Cell Significance Index: -41.3100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3360
    Cell Significance Index: -34.9900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.3384
    Cell Significance Index: -46.4700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3409
    Cell Significance Index: -39.7300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.3500
    Cell Significance Index: -45.2200
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.3567
    Cell Significance Index: -5.0000
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.3620
    Cell Significance Index: -15.7400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3722
    Cell Significance Index: -19.5400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.3994
    Cell Significance Index: -40.8000
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -0.4883
    Cell Significance Index: -3.5500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.4893
    Cell Significance Index: -11.7400
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.5083
    Cell Significance Index: -6.5100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.6063
    Cell Significance Index: -45.1900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.6090
    Cell Significance Index: -46.7300
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.6665
    Cell Significance Index: -13.3800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.7168
    Cell Significance Index: -22.8300
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.7245
    Cell Significance Index: -10.3000
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: -0.7599
    Cell Significance Index: -5.9600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.7984
    Cell Significance Index: -50.3200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.8002
    Cell Significance Index: -37.3100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.8054
    Cell Significance Index: -20.0900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.8224
    Cell Significance Index: -21.1400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.8361
    Cell Significance Index: -43.5500
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.8907
    Cell Significance Index: -18.5900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.9095
    Cell Significance Index: -31.8600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.9395
    Cell Significance Index: -44.1600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.9406
    Cell Significance Index: -30.8000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.9559
    Cell Significance Index: -10.8600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -1.0355
    Cell Significance Index: -17.3300
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -1.0642
    Cell Significance Index: -18.4000
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -1.1492
    Cell Significance Index: -11.3700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.2164
    Cell Significance Index: -42.2700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.2874
    Cell Significance Index: -47.2600
  • Cell Name: T-helper 17 cell (CL0000899)
    Fold Change: -1.3603
    Cell Significance Index: -10.3800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -1.3851
    Cell Significance Index: -19.8400
  • Cell Name: glioblast (CL0000030)
    Fold Change: -1.3854
    Cell Significance Index: -8.7000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.3954
    Cell Significance Index: -41.1000
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -1.3957
    Cell Significance Index: -20.6000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -1.4532
    Cell Significance Index: -41.4700
  • Cell Name: neural cell (CL0002319)
    Fold Change: -1.4589
    Cell Significance Index: -17.0200
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -1.4739
    Cell Significance Index: -20.6100
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -1.5214
    Cell Significance Index: -16.5400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -1.5274
    Cell Significance Index: -53.6700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -1.5531
    Cell Significance Index: -44.5200
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -1.5600
    Cell Significance Index: -20.3600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -1.5694
    Cell Significance Index: -41.9100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.6028
    Cell Significance Index: -42.8800
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: -1.6241
    Cell Significance Index: -14.7400
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -1.6264
    Cell Significance Index: -51.4400
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -1.6291
    Cell Significance Index: -25.8500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.7410
    Cell Significance Index: -36.9500
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -1.7468
    Cell Significance Index: -34.5400
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -1.7786
    Cell Significance Index: -36.1900
  • Cell Name: stromal cell of endometrium (CL0002255)
    Fold Change: -1.7808
    Cell Significance Index: -25.3300
  • Cell Name: neuron (CL0000540)
    Fold Change: -1.7924
    Cell Significance Index: -16.9900
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -1.8069
    Cell Significance Index: -46.0400
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -1.8373
    Cell Significance Index: -45.8900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -1.8392
    Cell Significance Index: -52.9900
  • Cell Name: monocyte (CL0000576)
    Fold Change: -1.8650
    Cell Significance Index: -21.4600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Structural role**: COL11A1 forms trimeric collagen fibrils, which are essential for the mechanical integrity and structure of the ECM. 2. **Tissue-specific expression**: The gene is highly expressed in cartilage, tendons, and the inner ear, highlighting its specific role in these tissues. 3. **Cell-type specificity**: COL11A1 is expressed in various cell types, including epithelial cells, neurons, and osteoblasts, indicating its involvement in multiple biological processes. 4. **Evolutionary conservation**: The COL11A1 gene is highly conserved across species, suggesting its essential role in maintaining tissue structure and function. **Pathways and Functions** 1. **Assembly of collagen fibrils**: COL11A1 plays a crucial role in the assembly of collagen fibrils, which are essential for the mechanical integrity of the ECM. 2. **Cartilage condensation**: The gene is involved in the condensation of cartilage, a process essential for the development of joints and other cartilaginous structures. 3. **Chondrocyte development**: COL11A1 is expressed in chondrocytes, the cells responsible for cartilage maintenance and development. 4. **Collagen biosynthesis and modifying enzymes**: The gene is involved in the biosynthesis and modification of collagen, which is essential for ECM structure and function. 5. **Mechanical stimulus detection**: COL11A1 is involved in the detection of mechanical stimuli, such as sound, which is essential for auditory function. **Clinical Significance** 1. **Musculoskeletal disorders**: Mutations in the COL11A1 gene have been associated with musculoskeletal disorders, such as osteogenesis imperfecta and spondyloepiphyseal dysplasia congenita. 2. **Cardiac abnormalities**: COL11A1 mutations have also been linked to cardiac abnormalities, including arrhythmias and congenital heart defects. 3. **Neurological disorders**: The gene is expressed in neurons and is involved in the development and function of the nervous system, suggesting its role in neurological disorders, such as autism and schizophrenia. 4. **Cancer**: COL11A1 has been implicated in cancer progression and metastasis, highlighting its potential as a therapeutic target. In conclusion, COL11A1 is a critical component of the extracellular matrix, and its dysregulation has been implicated in various diseases, including musculoskeletal, cardiac, and neurological disorders. Further research is needed to fully understand the functions of COL11A1 and its role in human disease.

Genular Protein ID: 1440024130

Symbol: COBA1_HUMAN

Name: Collagen alpha-1(XI) chain

UniProtKB Accession Codes:

P12107 B1ASK7 D3DT73 E9PCU0 Q14034 Q149N0 Q9UIT4 Q9UIT5 Q9UIT6

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CPTAC 2 CTD 1 ChEBI 5 ChEMBL 1 ChiTaRS 1 ComplexPortal 3 DMDM 1 DNASU 1 DisGeNET 1 EMBL 100 Ensembl 4 ExpressionAtlas 1 GO 26 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 9 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 4 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 6 RefSeq 4 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1690726

Title: Pro-alpha 1(XI) collagen. Structure of the amino-terminal propeptide and expression of the gene in tumor cell lines.

PubMed ID: 1690726

DOI: 10.1016/s0021-9258(19)39343-3

PubMed ID: 10486316

Title: Splicing mutations of 54-bp exons in the COL11A1 gene cause Marshall syndrome, but other mutations cause overlapping Marshall/Stickler phenotypes.

PubMed ID: 10486316

DOI: 10.1086/302585

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3182841

Title: Cloning and sequencing of pro-alpha 1 (XI) collagen cDNA demonstrates that type XI belongs to the fibrillar class of collagens and reveals that the expression of the gene is not restricted to cartilagenous tissue.

PubMed ID: 3182841

DOI: 10.1016/s0021-9258(18)37512-4

PubMed ID: 7721876

Title: Alternative mRNA processing occurs in the variable region of the pro-alpha 1(XI) and pro-alpha 2(XI) collagen chains.

PubMed ID: 7721876

DOI: 10.1074/jbc.270.16.9486

PubMed ID: 30245514

Title: Splice-altering variant in COL11A1 as a cause of nonsyndromic hearing loss DFNA37.

PubMed ID: 30245514

DOI: 10.1038/s41436-018-0285-0

PubMed ID: 8872475

Title: A family with Stickler syndrome type 2 has a mutation in the COL11A1 gene resulting in the substitution of glycine 97 by valine in alpha-1(XI) collagen.

PubMed ID: 8872475

DOI: 10.1093/hmg/5.9.1339

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 21035103

Title: Fibrochondrogenesis results from mutations in the COL11A1 type XI collagen gene.

PubMed ID: 21035103

DOI: 10.1016/j.ajhg.2010.10.009

PubMed ID: 20513134

Title: Stickler syndrome and the vitreous phenotype: mutations in COL2A1 and COL11A1.

PubMed ID: 20513134

DOI: 10.1002/humu.21257

Sequence Information:

  • Length: 1806
  • Mass: 181065
  • Checksum: 7CBF744263321B43
  • Sequence:
    • MEPWSSRWKT KRWLWDFTVT TLALTFLFQA REVRGAAPVD VLKALDFHNS PEGISKTTGF 
CTNRKNSKGS DTAYRVSKQA QLSAPTKQLF PGGTFPEDFS ILFTVKPKKG IQSFLLSIYN 
EHGIQQIGVE VGRSPVFLFE DHTGKPAPED YPLFRTVNIA DGKWHRVAIS VEKKTVTMIV 
DCKKKTTKPL DRSERAIVDT NGITVFGTRI LDEEVFEGDI QQFLITGDPK AAYDYCEHYS 
PDCDSSAPKA AQAQEPQIDE YAPEDIIEYD YEYGEAEYKE AESVTEGPTV TEETIAQTEA 
NIVDDFQEYN YGTMESYQTE APRHVSGTNE PNPVEEIFTE EYLTGEDYDS QRKNSEDTLY 
ENKEIDGRDS DLLVDGDLGE YDFYEYKEYE DKPTSPPNEE FGPGVPAETD ITETSINGHG 
AYGEKGQKGE PAVVEPGMLV EGPPGPAGPA GIMGPPGLQG PTGPPGDPGD RGPPGRPGLP 
GADGLPGPPG TMLMLPFRYG GDGSKGPTIS AQEAQAQAIL QQARIALRGP PGPMGLTGRP 
GPVGGPGSSG AKGESGDPGP QGPRGVQGPP GPTGKPGKRG RPGADGGRGM PGEPGAKGDR 
GFDGLPGLPG DKGHRGERGP QGPPGPPGDD GMRGEDGEIG PRGLPGEAGP RGLLGPRGTP 
GAPGQPGMAG VDGPPGPKGN MGPQGEPGPP GQQGNPGPQG LPGPQGPIGP PGEKGPQGKP 
GLAGLPGADG PPGHPGKEGQ SGEKGALGPP GPQGPIGYPG PRGVKGADGV RGLKGSKGEK 
GEDGFPGFKG DMGLKGDRGE VGQIGPRGED GPEGPKGRAG PTGDPGPSGQ AGEKGKLGVP 
GLPGYPGRQG PKGSTGFPGF PGANGEKGAR GVAGKPGPRG QRGPTGPRGS RGARGPTGKP 
GPKGTSGGDG PPGPPGERGP QGPQGPVGFP GPKGPPGPPG KDGLPGHPGQ RGETGFQGKT 
GPPGPGGVVG PQGPTGETGP IGERGHPGPP GPPGEQGLPG AAGKEGAKGD PGPQGISGKD 
GPAGLRGFPG ERGLPGAQGA PGLKGGEGPQ GPPGPVGSPG ERGSAGTAGP IGLPGRPGPQ 
GPPGPAGEKG APGEKGPQGP AGRDGVQGPV GLPGPAGPAG SPGEDGDKGE IGEPGQKGSK 
GDKGENGPPG PPGLQGPVGA PGIAGGDGEP GPRGQQGMFG QKGDEGARGF PGPPGPIGLQ 
GLPGPPGEKG ENGDVGPMGP PGPPGPRGPQ GPNGADGPQG PPGSVGSVGG VGEKGEPGEA 
GNPGPPGEAG VGGPKGERGE KGEAGPPGAA GPPGAKGPPG DDGPKGNPGP VGFPGDPGPP 
GEPGPAGQDG VGGDKGEDGD PGQPGPPGPS GEAGPPGPPG KRGPPGAAGA EGRQGEKGAK 
GEAGAEGPPG KTGPVGPQGP AGKPGPEGLR GIPGPVGEQG LPGAAGQDGP PGPMGPPGLP 
GLKGDPGSKG EKGHPGLIGL IGPPGEQGEK GDRGLPGTQG SPGAKGDGGI PGPAGPLGPP 
GPPGLPGPQG PKGNKGSTGP AGQKGDSGLP GPPGSPGPPG EVIQPLPILS SKKTRRHTEG 
MQADADDNIL DYSDGMEEIF GSLNSLKQDI EHMKFPMGTQ TNPARTCKDL QLSHPDFPDG 
EYWIDPNQGC SGDSFKVYCN FTSGGETCIY PDKKSEGVRI SSWPKEKPGS WFSEFKRGKL 
LSYLDVEGNS INMVQMTFLK LLTASARQNF TYHCHQSAAW YDVSSGSYDK ALRFLGSNDE 
EMSYDNNPFI KTLYDGCASR KGYEKTVIEI NTPKIDQVPI VDVMINDFGD QNQKFGFEVG 
PVCFLG

Genular Protein ID: 4023639274

Symbol: Q59HB5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59HB5

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 3 SAM 1 SMART 1

Sequence Information:

  • Length: 1017
  • Mass: 99966
  • Checksum: A50D0DB279FA164F
  • Sequence:
    • KVTEEKLVKL AQEGKMALKD PKVEQAQLET QVLQVKQEKR ENLEFQDYQD IQEDKVQRIS 
DVIGSTGFPG FPGANGEKGA RGVAGKPGPR GQRGPTGPRG SRGARGPTGK PGPKGTSGGD 
GPPGPPGERG PQGPQGPVGF PGPKGPPGPP GKDGLPGHPG QRGETGFQGK TGPPGPGGVV 
GPQGPTGETG PIGERGHPGP PGPPGEQGLP GAAGKEGAKG DPGPQGISGK DGPAGLRGFP 
GERGLPGAQG APGLKGGEGP QGPPGPVGSP GERGSAGTAG PIGLPGRPGP QGPPGPAGEK 
GAPGEKGPQG PAGRDGVQGP VGLPGPAGPA GSPGEDGDKG EIGEPGQKGS KGDKGENGPP 
GPPGLQGPVG APGIAGGDGE PGPRGQQGMF GQKGDEGARG FPGPPGPIGL QGLPGPPGEK 
GENGDVGPMG PPGPPGPRGP QGPNGADGPQ GPPGSVGSVG GVGEKGEPGE AGNPGPPGEA 
GVGGPKGERG EKGEAGPPGA AGPPGAKGPP GDDGPKGNPG PVGFPGDPGP PGELGPAGQD 
GVGGDKGEDG DPGQPGPPGP SGEAGPPGPP GKRGPPGAAG AEGRQGEKGA KGEAGAEGPP 
GKTGPVGPQG PAGKPGPEGL RGIPGPVGEQ GLPGAAGQDG PPGPMGPPGL PGLKGDPGSK 
GEKGHPGLIG LIGPPGEQGE KGDRGLPGTQ GSPGAKGDGG IPGPAGPLGP PGPPGLPGPQ 
GPKGNKGSTG PAGQKGDSGL PGPPGPPGPP GEVIQPLPIL SSKKTRRHTE GMQADADDNI 
LDYSDGMEEI FGSLNSLKQD IEHMKFPMGT QTNPARTCKD LQLSHPDFPD GEYWIDPNQG 
CSGDSFKVYC NFTSGGETCI YPDKKSEGVR ISSWPKEKPG SWFSEFKRGK LLSYLDVEGN 
SINMVQMTFL KLLTASARQN FTYHCHQSAA WYDVSSGSYD KALRFLGSND EEMSYDNNPF 
IKTLYDGCAS RKGYEKTVIE INTPKIDQVP IVDVMINDFG DQNQKFGFEV GPVCFLG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.